LymeNet Flash: which types of abx are both intracellular, and cross the BBB?

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»	LymeNet Flash » Questions and Discussion » Medical Questions » which types of abx are both intracellular, and cross the BBB?

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Topic: which types of abx are both intracellular, and cross the BBB?

VB
LymeNet Contributor
Member # 16824

posted

I have read that the intracellular form of lyme resides in the brain too. I know there are very few oral abx that cross the BBB, let alone are intracellular too.

I'm assuming mino would be one. Is ketek one? Are there any others? Is flagyl intracellular (I know it's a cyst buster, but not sure if intracellular).

Thanks!
V

Posts: 453 | From TX | Registered: Aug 2008 | IP: Logged |

bcb1200
Frequent Contributor (1K+ posts)
Member # 25745

posted

Doxy is one. I believe Biaxin and Zith also.

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2/10 symptoms began
5/10 dx'd, after 3 months numerous test and doctors

IgM Igenex +/CDC +
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Currently on:

Currently at around 95% +/- most days.

Posts: 3134 | From Massachusetts | Registered: May 2010 | IP: Logged |

blinkie
Frequent Contributor (1K+ posts)
Member # 14470

posted

my LLMD says Ketek is intracellular...I'm taking it now.

Posts: 1104 | From N.California | Registered: Jan 2008 | IP: Logged |

VB
LymeNet Contributor
Member # 16824

posted

I didn't think Biaxin, or Zith crossed the BBB? I thought the only macrolide that got into the brain in high enough doses to kill stuff was possibly Ketek?

Also, does doxy cross BBB? If given in high enough doses?

Thanks all,
V

Posts: 453 | From TX | Registered: Aug 2008 | IP: Logged |

Maradona
LymeNet Contributor
Member # 24552

posted

Bicilin ,Rocephin,Vancomycin ,Roxithromycin are the best to cros BBB.The other Drugs you have to take them in high doses to cros BBB.

Posts: 482 | From Nebraska | Registered: Feb 2010 | IP: Logged |

lymewreck36
Frequent Contributor (1K+ posts)
Member # 4395

posted

Be careful. Rocephin and that class of antibiotics are NOT intracellular. Rocephin alone will not cure lyme.

Mary

Posts: 1032 | From North Carolina | Registered: Aug 2003 | IP: Logged |

cactus
Frequent Contributor (1K+ posts)
Member # 7347

posted

Somewhere I have a detailed chart about this, but can't find it at the moment.

Here, though, is a very old thread with an excellent post on this topic by minoucat. Scroll down to read that post:

http://flash.lymenet.org/ubb/Forum1/HTML/032580.html

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�Did you ever stop to think, and forget to start again?� - A.A. Milne

Posts: 1987 | From No. VA | Registered: May 2005 | IP: Logged |

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