Dogsandcats
Frequent Contributor (1K+ posts)
Member # 28544
posted
I know there have been posts on his recently. I just got my blood work back and it shows on the IGG I am high. It says it does not differentiate between past or present infections.
So this means the final decision of whether it is alive and unwell in me would be thru a clinical observation?
Is this test regarded like other Lyme test -by the mainstream- as not reliable?
The IGM is normal. I had also just started malarone and augmentin.
Any particular supplements I should be taking?
Is this why I am so tired and always running a few quarts low?
-------------------- God will prepare everything for our perfect happiness in heaven, and if it takes my dog being there, I believe he'll be there.
Billy Graham Posts: 1967 | From California | Registered: Oct 2010
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manybites
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posted
Is it mucoplasma pneumoniale or fermentas.The last one is severe.
Posts: 1379 | From disable | Registered: Aug 2011
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Dogsandcats
Frequent Contributor (1K+ posts)
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posted
M. pneumoniae
-------------------- God will prepare everything for our perfect happiness in heaven, and if it takes my dog being there, I believe he'll be there.
Billy Graham Posts: 1967 | From California | Registered: Oct 2010
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jackie51
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posted
My daughter's neurologist said that is past infection, but I wouldn't bet the farm on that.
Posts: 1374 | From Crazy Town | Registered: Dec 2007
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manybites
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posted
I do not agree.It came out that bartonella that showed up as a past infection in my daughter reacted right away on homepathic formula that I gave her.
That made me beilieve that not only she never fought it completly but was staying there to spread when the time rises.
So she did 6 moths treatment for it.BUt in time 2 years later she still shows some symtoms as prior to that she had some in her brain .
Time to treat it again as it has reached the brain and I do not care if it showes past infection.It is in the system and needs to be treated and killed before become activated again and she is very emotional as it has activated the layer in the brain .I wish I knew about her issues long time ago before spreads in the brain .
As for M Pneumoniale I would start minocycline and most of all take enzymes prior to it.It need to be adressed as a coinfection as well.
Posts: 1379 | From disable | Registered: Aug 2011
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sammy
Frequent Contributor (5K+ posts)
Member # 13952
posted
I also test positive for mycoplasma p. It needs treated long term like Lyme. Combos of meds are usually most effective like doxy or mino + zith or biaxin, some also add rifampin. Quinolones can be effective as a stand alone therapy.
Dogsandcats
Frequent Contributor (1K+ posts)
Member # 28544
posted
thank you all. I am a bit befuddled (my new word - as long as I don't hurry and mispronounce it and say a bad word).
It would explain the horrible fatigue. I have other friends too - Babs, Bart and something else that is lost in the list.
I am surprised that after my llmd got the lab report that he hasn't added it to my malarone and augmentin.
Another fun filled day in the world of joyous Lyme!
-------------------- God will prepare everything for our perfect happiness in heaven, and if it takes my dog being there, I believe he'll be there.
Billy Graham Posts: 1967 | From California | Registered: Oct 2010
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jackie51
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posted
I have attributed my fatigue to babesia because when I treated that, it finally lifted. I have had fatigue my entire life, it only got worse after having kids. Now, I only need say 7 hrs of sleep. Unheard of even 1 year ago.
Myco also causes fatigue along with other symptoms similar to babs, so if you've already treated babs and you're still tired, then myco seems like your next co-infection.
Your llmd may be hitting one infection at a time. That's what mine did. Sometimes we're killing stuff we didn't even know we had too. Bonus, yippee!
Good luck.
Posts: 1374 | From Crazy Town | Registered: Dec 2007
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Dogsandcats
Frequent Contributor (1K+ posts)
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posted
It would be nice if one med caught a couple of bugs....doesn't seem to be the case.
I think I am just at a very impatient time where I want all things NOW!
The big joke is never ask for patience...
-------------------- God will prepare everything for our perfect happiness in heaven, and if it takes my dog being there, I believe he'll be there.
Billy Graham Posts: 1967 | From California | Registered: Oct 2010
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Garth Nicolson - Mycoplasma - Often Overlooked in Chronic Lyme Disease
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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momintexas
Frequent Contributor (1K+ posts)
Member # 23391
posted
I think the jury is still out on high IgG only.
I can tell you from our experience and from what one of our Dr's has said, if you are still not well and have high IgG then it needs to be taken into consideration.
One of our Dr's feels that it could be a sign of a chronic ongoing infection.
It takes a very very long time for myco p to go away. Treatment of six 6 weeks cycles minimum has been suggested.
It has taken us longer than that. Fatigue with it has been awful.
If your IgG is still high - it probably would be worth looking into.
The tetracycline family seems to get the best response.
Hope you feel better soon.
Posts: 1408 | From Tx | Registered: Nov 2009
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Dogsandcats
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posted
Thank you, getting a tad discouraged.
-------------------- God will prepare everything for our perfect happiness in heaven, and if it takes my dog being there, I believe he'll be there.
Billy Graham Posts: 1967 | From California | Registered: Oct 2010
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CherylSue
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Member # 13077
posted
I had been on cumunda, doxycycline, azithromycin, and biaxin, but nothing seemed to touch my myco pneu. really well.
My second LLMD had me on Lauricidin for viruses and myco pneu.
My third LLMD has me on Researched Nutritional's TransferPlasmyc for both HHV6 and mycoplasma pneu. I still take the lauricidin, too.
I now sleep about 7 hours a night and work full time. I still get fatigued easily and have to pace myself, but I manage.
I'll be seeing my 3rd LLMD soon, and if he runs another another myco test (Igg was high before) we can get an idea if I'm going in the right direction. I still have an active Lyme infection according to my C3a and C4a lab tests.
Posts: 1954 | From Illinois | Registered: Aug 2007
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posted
What are the symptoms of mycoplasma? Is there a lab that runs both mycoplasma p. and mycoplasma f. tests?
Posts: 618 | From NC | Registered: Oct 2009
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momintexas
Frequent Contributor (1K+ posts)
Member # 23391
posted
The first 2 are links to previous discussions here on lymenet.
This can be a very stubborn infection to get rid of.
Here's some good info and links about it.
Immune Disruption
"Mycoplasmas can also disrupt the normal orchestration and organization of the host�s immune system. They can cause lymphocytes (white blood cells that bear the major responsibility of the immune system) to secrete inflammatory cytokines (proteins that facilitate cell-to-cell communication), which leads to swelling, inflammation and either stimulation or suppression of the immune system. "
"Mycoplasma are a group of microorganisms which are a cross between a virus and a bacteria. Together with Chlamydia and Rickettsia they make up a family of microorganisms known as Rickettsiae and Pararickettsiae. They are found everywhere, the hosts are usually rodents and the vectors are arthropods (insects with jointed legs) or airborne through dust. Rickettsial organisms have been found in ticks, lice, fleas, mites, meat, milk, stool and dust.
They are the smallest free living organisms. Like viruses, they are intracellular organisms but unlike viruses, they can reproduce outside cells. They lack a cell wall which makes them resistant to many antibiotics. They enter the body through skin, lungs or digestive system. They then spread through the bloodstream to infect vascular endothelium. They multiply within cells until numbers are so great that the cells burst. This then damages blood flow to multiple organs, hence the multitude of symptoms which may occur.
Research by Dr Cecile Jardin (a French surgeon now based in South Africa and specialising in the treatment of chronic fatigue) has shown that the most common symptoms of chronic mycoplasma type infections include:
Symptoms are caused by the release of 3 types of toxins into the blood:
1. Endocytokines that cause inflammation and pain. 2. Neurocytokines that produce neurological symptoms including the demyelinisation found in multiple sclerosis and psychiatric symptoms such as depression and anxiety. 3. Allergens causing allergies.
Mycoplasma infections can be occult. That means they can be asymptomatic and lie dormant until another bacteria, virus, parasite, stress or toxin activates it and causes the symptomatic phase.
Often these chronic conditions improve dramatically and even completely recover once the infection is identified and appropriately treated. In my opinion, everyone with the above conditions should be screened for chronic mycoplasma infection."
"Acute mycoplasma infections can be diagnosed by seeing an elevation in mycoplasma antibodies in a blood test. However, chronic infections often require specialised DNA testing (polymerase chain reaction). Clues to a persistent mycoplasma infection include an elevation in inflammatory markers like C-reactive protein, low white cell count, unexplained elevation of liver enzymes, elevated thyroid antibodies (in 28%) an elevated ESR, elevated rheumatoid factor, elevated antinuclear antibody and an elevated IgM antibody."
"Autoimmune conditions associated with Mycoplasmas include arthritis, Fibromyalgia, myositis, thyroid dysfunction (Hashimoto�s or Grave�s Diseases), and adrenal dysfunction, signs and symptoms of Lupus, Multiple Sclerosis, Lyme,and Lou Gehrig�s Disease.
The Mycoplasma organism has the capacity to invade cells, tissues and blood, producing systemic infections in numerous organ systems. According to Dr. Nicholson, it can penetrate the central and peripheral nervous system. Because it has the ability to damage the immune system by invading the natural killer cells (NK cells) of the lymphocytes, it weakens them, reduces their numbers, and renders them susceptible to viral infections, such as Human Herpes Virus 6 (HHV6), HHV7 or HHV8. It may also explain some of the environmentally sensitive responses that are seen with CFIDS and MCS.
Mycoplasma infection can trigger inflammatory cytokine over-production that is commonly seen in CFS/FMS. With the induction of CD-4+ helper cells of the immune system, an over production of cytokines such as Interleukin-1, Interleukin-6 and Tumor Necrosis Factor-alpha occurs. These elevated cytokines have been implicated in the development of many of the CFS/FMS symptoms, including neurological involvement. They can have specific or nonspecific stimulatory or suppressive effects on lymphocytes, as measured by B and T cell activation.
In addition, the Mycoplasma infection has immune-modulating effects, activating the hypothalamic-pituitary-adrenal axis. This can cause a cascade of limbic system symptoms characteristic of CFS/FMS."
"Due to the lack of a cell wall, all mycoplasmas are innately resistant to all beta-lactams and glycopeptides. Sulfonamides, trimethoprim, polymixins, nalidixic acid, and rifampin are also inactive. Linezolid is the prototype agent of the oxazolidinone class. These agents are much less active against M. pneumoniae than the other agents that inhibit protein synthesis (224). New quinolones such as moxifloxacin, gatifloxacin, garenoxacin, gemifloxacin, and sparfloxacin tend to have somewhat greater in vitro activity than older agents such as ciprofloxacin, ofloxacin, and levofloxacin, although MICs of all fluoroquinolones are severalfold higher than those of macrolides (224, 435-437). Fluoroquinolones have been shown to be bactericidal for M. pneumoniae, whereas macrolides and tetracyclines are primarily bacteriostatic"
susank
Frequent Contributor (1K+ posts)
Member # 22150
posted
OP - you could have the levels checked again. If the IGG is higher that might mean something. I think that Labcorp does the test where your numbers are given. ie 250, 600 etc. I'm not sure what Quest does - but I think their test is the "greater than" kind of results - which I don't think tells enough. ie >7 or such
I tested with TARCI a couple of years ago. I think they do a M.Fermentans test. The Arthritis Research Center. On a post of mine within last few months I listed the tests they offered.
-------------------- Pos.Bb culture 2012 Labcorp - no bands ever Igenex - Neg. 4 times With overall bands: IGM 18,28,41,66 IND: 23-25,34,39 IGG 41,58 IND: 39 Bart H IGG 40 Posts: 1613 | From Texas | Registered: Aug 2009
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