tricia386
Frequent Contributor (1K+ posts)
Member # 29623
posted
Is crypto toxic I have read conflicting information
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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Keebler
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posted
- Cryptolepis sanguinolenta is not toxic to humans (but is cytotoxic to certain protozoal infections) when used correctly as an herbal tincture according to direction. It has valuable potential.
I've used it myself and have done very well with no problems at all. As with everything I consume, I've researched this as much as possible.
I've never seen any credible author discuss problems. Still, I'd really like to see what you read.
Can you post the link(s)?
It's important to see where that has been written, by whom and and exactly in what context. There may be a simple explanation.
Cryptolepis sanguinolenta � 38 abstracts -
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lululymemom
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posted
The way it was explained to me is that it is quite toxic if taken in large doses. The recommended treatment time is 2 months. If the problem has not resolved and you are seeing improvement it is okay to stay with it longer. Just not to exceed the recommended dose.
Bartonella henselae 1:100 Posts: 2027 | From British Columbia | Registered: Jun 2010
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Keebler
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posted
- A lot of things can be toxic if taken in too large of dose - or for too long - or combined with the wrong things, etc. It is important to remember that for everything. Also why it's vital to get a LLMD's guidance.
Lululymemom, do you have a link that discusses those dosage ranges? It's good to know what they consider the top range.
I'd like to have that for my reference file and to see how it fits in with other works - and if the dose directions vary depending upon infection.
Thanks. -
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Keebler
Honored Contributor (25K+ posts)
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Clinical efficacy of a tea-bag formulation of cryptolepis sanguinolenta root in the treatment of acute uncomplicated falciparum malaria.
Bugyei KA, Boye GL, Addy ME.
Department of Pharmacology, University of Ghana Medical School, College of Health Sciences, University of Ghana, Accra, Ghana.
Excerpt:
Conclusion:
On the basis of fever clearance and disappearance of parasitaemia by Day 7, the formulation has been shown to be non-toxic and highly effective in the treatment of acute uncomplicated malaria. -
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lululymemom
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posted
Our ND advised us on the use of Cryptolepis. One tsp. 3X per day is considered a large dose. I also looked up several references to long term use and here is one from Stephen Buhner. There are others I just don't have the time to look for them right now.
I am not aware of any side effects from the use of cryptolepis, however most traditional use has been of limited duration as has most trial studies on the herb. The physical impacts of the long term use of cryptolepis are unknown. I generally prefer limiting its use to 3 months at large doses, 6 months at lower doses.
Bartonella henselae 1:100 Posts: 2027 | From British Columbia | Registered: Jun 2010
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tricia386
Frequent Contributor (1K+ posts)
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posted
All I know is I'm herxing my butt off 15 mins after I take it.
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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lululymemom
Frequent Contributor (1K+ posts)
Member # 26405
posted
Here is one more reference that addresses the long term use of cryptolepis:
If there were no toxicity issues, I'm sure Stephen would not limit it's use. Not enough studies have been done to prove or disprove this issue.
If it truly is a herx reaction, it should be short lived with some relief afterward..
We have an LLMD here that believes co-infection die off does not cause herx reactions. That is another debatable issue. Do parasitic infections have a die off similar to bacterial infections and is there a healing crisis? Some think not..
Bartonella henselae 1:100 Posts: 2027 | From British Columbia | Registered: Jun 2010
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Keebler
Honored Contributor (25K+ posts)
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posted
- lululymemom,
Thanks so much for those links. They will help everyone.
I guess when asked if something is toxic, I just think that it's assumed "with medical guidance regarding dose, timing, etc."
but it's good to see -- - oops - phone rang - -
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feelfit
Frequent Contributor (1K+ posts)
Member # 12770
posted
my Dr. read a Cryptolepis article I gave him a few weeks ago. he says it simulates the production of adrenalin and noradrenalin, which affect systolic and diastolic pressures respectively. In addition, it's cytotoxic for mammalian cells, not just for infected or cancerous cells. Cells period. also damages DNA.
lululymemom
Frequent Contributor (1K+ posts)
Member # 26405
posted
keebler, yes, you are correct that mostly it is assumed in order to make administration safer..
and feelfit, that is a good article.. that is one that I have come across.. blood pressure can be an issue especially with babesia which can cause NMH(neurally mediated hypotension) and POTS(Postural Orthostatic Tachycardia Syndrome)...
Bartonella henselae 1:100 Posts: 2027 | From British Columbia | Registered: Jun 2010
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manybites
Frequent Contributor (1K+ posts)
Member # 33750
posted
When I use it I get chills and cold waves rushed to the bones and my legs.
I used to sweat around my gut and liver now not anymore.
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pamoisondelune
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Member # 11846
posted
I read an Oxford research article from 2003 that said cryptolepis is "profoundly cytotoxic" and should be evaluated for use as a possible cancer drug.
I worried about what cytotoxic means---- toxic to all cells or just to cancer cells? I have an impression that "cytotoxic" is a good quality referring to killing cancer cells; is that the way specialists use the word?
Sorry i don't have the link.
---PollyPolygonum
Posts: 1226 | From USA | Registered: May 2007
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