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That's a really fascinating article. Wow, if they can acknowledge that some bacteria develop "persisters" a form that can't be killed by current antibiotics, and that stay in a dormant state....that sure sounds like Lyme cysts, doesn't it!
Between studies like that and the mainstream docs finally talking about biofilms... maybe they will finally find a solution to chronic infections.
-------------------- Son, 26, Dx Lyme 4/10, Babs 8/10 Had serious arthritis, all gone. Currently on Valtrex Daughter, 26,bullseye 7/11 arthritis in knees, cured and off all meds. . Self:Lyme, bart, sxs gone, no longer treating. Posts: 496 | From Washington, DC | Registered: Jul 2010
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"While antibiotics can penetrate those biofilms, they fail to clear up the infection because of so-called “persister cells”.
These are hibernating cells within the biofilm that stop dividing or growing and shut down their metabolism.
The dormant cells are the main cause of chronic and relapsing bacterial infections, since conventional antibiotics can target only actively growing bacterial cells.
“We had to look for something that in a persister will activate a function, will corrupt it, force it to kill the cell,” said Lewis."
Posts: 922 | From Philadelphia | Registered: Sep 2012
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posted
"They have found that persisters achieve their singular goal by entering a dormant state that makes them impervious to traditional antibiotics. Since these drugs work by targeting active cellular functions, they are useless against dormant persisters, which aren’t active at all. For this reason, persisters are critical to the success of chronic infections and biofilms, because as soon as a treatment runs its course, their reawakening allows for the infection to establish itself anew.
A recent study found that a drug called ADEP effectively wakes up the dormant cells and then initiates a self-destruct mechanism."
Posts: 922 | From Philadelphia | Registered: Sep 2012
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