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» LymeNet Flash » Questions and Discussion » Medical Questions » Biaxin and Trazodone

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Author Topic: Biaxin and Trazodone
Samlyme
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My ID dr just prescribed trazadone to help me sleep. I'm on biaxin. I've read that these two medications can effect a cardiac arrhythmia and should not be taken together unless absolutely necessary. Is 25 mg too low a dose to have any interactions?
Posts: 154 | From Boston | Registered: May 2014  |  IP: Logged | Report this post to a Moderator
Lymetoo
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They certainly can cause trouble!! I found out that trazodone was causing a LOT of heart problems for me. I'm also unable to take Biaxin .. same reason.

The combo would not be a good thing .. but MAYBE 25 mg would be OK.

If you have any trouble at all, let your doctor know about it.

Ambien might be better for you.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
Keebler
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I would not chance it, at all. Trazadone, even at low dose, caused me lots of trouble before I knew lyme was involved. It took me many other sleeping pill mistakes over years but I finally learned that any sleeping drug and I do not dance well together, at all. There are many other ways to approach this.


http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/89790

Topic: NATURAL SLEEP & ADRENAL SUPPORT
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Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
Keebler
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Sam,

Two weeks ago you posted that you take (or had taken?) Glutamine supplements.

In case you still do, or just important to know: Glutamine can cause insomnia, big time. It's not good for those with lyme to have any excess over what's naturally found in some foods.

[Unless, perhaps, to help repair stomach lining that may be in urgent need -- but then, as little as possible balanced with other things to lessen its neuro-excitability effect.]

Great detail here on how excitatory & toxic it can be to our nerve fibers. Check all protein powder formulas, too, as they often contain high amounts of this, above the daily average intake.

http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/113775?#000000

Topic: Amino Acid Information Link

See post: Caution: Aspartate; Glutamine; and Phenylalanine (3 excitatory amino acids that can be wrong for us when added as supplements, beyond a normal dietary level)

Seaweed has its own natural MSG and can be very excitatory
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Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
Samlyme
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Gah! Thanks for the heads up on the Glutamine. I only just started taking it again this week. I had taken it years ago but very infrequently.

My Dr. just recently recommended it because according to tests it shows that I seem to develop food intolerances to everything I eat regularly.

I'm trying to rotate my diet more but it's hard when you're already excluding so many things. I can cut out the Glutamine and work with bone broth soups or something if it's going to add to my insomnia issues.

I think it's actually been the Biaxin itself that's worsening my insomnia. I had somewhat more of a handle on it before I started that.

I'm so reluctant to try and change my antibiotic regimen. Who knows what side effects I'll have to contend with on something else. Then there's the whole hellish new med adjustment phase.

I have been taking 5-HTP, Melatonin and Kavinace before bed and it worked all right at first but as is typical with me and supplements it works less and less over time.

One of my Dr.s suggested I up the dose of melatonin and 5-HTP so I'm now taking what seems like a handful of them before bed and haven't noticed much difference.

I feel like the Kavinace and 5HTP have helped with general anxiety issues though so that's nice.

Sleep deprivation is certainly an effective form of torture. You find yourself willing to try anything…

My problem is that I consistently wake up at 3 AM. And I'm just all of a sudden as awake as I would be at 2 in the afternoon.

Before I started the Biaxin I had managed to push the schedule back to waking up at four. For some reason that feels more manageable.

For a long time I would get up and go for an hour long walk at 6 am every day just to tire myself out in hopes to sleep through the night. That sort of worked for a while but in retrospect I was a bit of a zombie most days.

Thanks for the feedback on your experience with that combo Lymetoo.

Keebler, that's a pretty long and impressive sleep thread. I'll definitely look into your suggestions.

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Lymetoo
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Yes, Biaxin can also cause insomnia.

I think 5HTP is similar to trazodone. You can Google that.

--------------------
--Lymetutu--
Opinions, not medical advice!

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Samlyme
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I did see that the mechanism of action (or whatever the language is) was similar for 5-HTP and Trazadone, they both effect the same neurotransmitters, so I was somewhat hopeful.

I noticed the interaction checker doesn't flag the combo of 5-HTP and Biaxin as a problem though.

http://www.webmd.com/interaction-checker/

I used this site to check for possible interactions with this drug and all my antibiotics just because a different Dr. than the one prescribing the antibiotics prescribed it so I wanted to double check for interactions.

Then I scanned past threads here. I saw your previous comments on it and a few others and I think someone else mentioned that their daughter had seizures and hallucinations so that was enough info to get me to put the bottle back on the shelf for a bit.

The problem is if you avoid everything based on the possibility of adverse effects you wouldn't ever take anything. And some drugs with many possible adverse effects have helped me significantly.

BUT I don't think I saw anyone say that they took that combo and it was great so that just adds to my hesitance. Maybe I'll suffer along with the insomnia and see if I can get switched off the biaxin.

For some reason Lyme destroyed my ability to tolerate even a thimble of coffee so that's not even an option. (insert grumbling) You have to wonder if these TBD's are actually sadistic with the many ways they manage to torment us.
(This is obviously the sleep deprivation talking) :-)

Posts: 154 | From Boston | Registered: May 2014  |  IP: Logged | Report this post to a Moderator
   

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