Just curious as to whether or not anyone has some good resource links on this subject? Abx undoubtedly did me well while I was on them, but, the necessity of their longer-term use surely came with some costs. Anyways, just wondering if decent articles proving a causal relationship between certain abx usage and subsequent mitochondrial dysfunction -in some people predisposed to such mitochondrial myopathies, that is- exist. I've seen articles hinting at this subject in the past, but, am hopeful that more valid and in-depth reviews are actually published. I'm certainly very sorry for what may seem like a lack of effort in searching...however, this upcoming SSDI appeals hearing has me very consumed!
Again, fellow LN users here, many thanks! Told you... Posts: 315 | From Negative (-) to positive (+) | Registered: Nov 2011
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- I can't read your post so I'm going just on the heading.
As for whether or not certain Rx (antibiotics, particularly you mention) can damage mitchondria, that is certainly a good question.
But, lyme - alone - can damage mitochrondria, big time. So, while it's important to consider all aspects of any Rx, OTC and supplements . . . somehow, it is absolutely essential that lyme be address as fully as possible.
The toxicity from lyme is what damages the mitochondria.
Along with whatever treatment that is going to be DIRECT against lyme, the key is to have good support / nutrients / habits in place as best possible at all times. -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
Phoiph
Frequent Contributor (1K+ posts)
Member # 41238
posted
There is a lot of information on the effects of antibiotics on mitochondria...here are links to 2 articles:
The Downside of Antibiotics? Bacteria-killing antibiotics might also damage a person’s tissues
posted
Keebler and Phoiph, thank you so much for your replies. They are much appreciated!!!
And Phoiph, you've actually passed along the articles that I saw in the past but was unable to come up with again. So, kudos for sharing!
The mitochondrial aspect is an interesting one, and, it is important to make sure that one who has such dysfunction weighs out their tbd treatment accordingly. Of course, stealth bacterial (and probably viral, protozoan/parasitic) infections can cause disruption in one's mitochondria, but, it will always be wise to ensure that the medicines (or any other treatment) employed to treat these pathogens are also not potential sources of its (mitochondrial) destruction.
Again, many thanks to the two of you for your helpfulness!
Told you...
Posts: 315 | From Negative (-) to positive (+) | Registered: Nov 2011
| IP: Logged |
Judie
Frequent Contributor (1K+ posts)
Member # 38323
posted
Judie- thank you so much for these add'l articles. The Quinolones are so toxic! I appreciate you taking the time to read and contribute to this post.
unsure445- you can say that again! If only that were the case for the majority of LN users! We're all here for a few similar reasons, right?!
Again, thank you friends for assisting!
Told you...
Posts: 315 | From Negative (-) to positive (+) | Registered: Nov 2011
| IP: Logged |
Phoiph
Frequent Contributor (1K+ posts)
Member # 41238
posted
On a more positive note, mHBOT is a very healing to mitochondria:
Positive Effects of Hyperbaric Oxygenation in Certain Mitrochondrial Cytopathies; by Dr. Neubauer:
Judie
Frequent Contributor (1K+ posts)
Member # 38323
posted
Told you I was sick - Glad to help.
It was my 8th day of oral levaquin that made me crippled for 2 months and ruined my body beyond Lyme.
The doc originally wanted to do IV avelox and I refused. So glad that I did. I'd be in a wheelchair permanently if I did that.
There needs to be a balance between aggressive and appropriate treatment.
Had I jumped to aggressive with IV, I'd be in a world of pain with what the doc wanted to put me on.
The doc REALLY pushed IV.
I did IM bicillin and tried IM rocephin first. I couldn't tolerate rocephin, so I didn't see the point in doing IV, so the doc pushed IV avelox.
Posts: 2839 | From California | Registered: Jul 2012
| IP: Logged |
CherylSue
Frequent Contributor (1K+ posts)
Member # 13077
posted
Good info. Thanks.
Posts: 1954 | From Illinois | Registered: Aug 2007
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/