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» LymeNet Flash » Questions and Discussion » Medical Questions » Duration of IV ABX?

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Author Topic: Duration of IV ABX?
tempe
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Articles posted in the past have shown borrelia bacteria turning into cyst form within 24-48 hours of exposure to antibiotics like rocephin & penicillins.

Why, then, do LLMDs prescribe those IV antibiotics for 8-10 weeks? Wouldn't most spirochetes be in cyst form after the first couple of weeks, so that the additional weeks of IV abx couldn't kill them anyway?

Why not just a couple of weeks of IV followed immediately by flagyl?

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NP40
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Not all of the Bb will go into cyst form ?Good question, anyone ?
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Troup Brazelton
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The good LLMDs then add some type of mepron to bust the cyst. The continued abx in the blood stream kills any blebs trying to re-establish in other places. The IV approach allows your intestinal tract a little breathing room and allows an easy change in abx. You can also take a lower dose of some types of abx thru IV as it is easily distributed into the body instead of absorbed. Just my opinion!
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Troup Brazelton
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I should add that there has been a 4 week cycle with or with out the abx. So keeping the level up for the cycles are important.
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janet thomas
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Troup B--

Mepron (atavaquone-a ubiquinone) is a cyst buster?? Please educate me about this, I thought cyst busters were flagyl & tinidazole (5-nitroimidazoles).

Thanks, Janet

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tempe
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Troup Brazelton
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You, as always, are correct. I was going to say Flagyl, but didn't want to limit choice and used mepron which isn't correct. Metron short for metronidazole would have been closer.
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