I can't believe that the CDC is that stupid, calling it negative. That's nuts!
23-25: Outer surface protein C (osp C).
30: Possibly a variant of outer surface protein A.
31: Outer surface protein A (osp A). 34: Outer surface protein B (osp B).
39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.
41: Flagella or tail. This is how Borrelia burgdorferi moves around, by moving the flagella. Many bacteria have flagella. This is the most common borreliosis antibody.
from the above link, "The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93."
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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posted
Does this site have a " resident " LLMD that answers ???. When my LLMD called me ( DR C in Westchester NY)he did not seem convinced?? Seeing him next Thursday. I googlede around and have found much info on bands 30 and 31 leaning towards the Positive side of Lyme testing. Betty G you have posted a lot and are somwhat and " expert " here. What ? should I ask of the Dr.
Posts: 355 | From NY | Registered: Jan 2006
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quote:Originally posted by 6t5frlane: Does this site have a " resident " LLMD that answers ???.
No. Sorry.
I would ask him why he's not convinced when Igenex IS??
If he still thinks you're negative, give him a printed version of Dr C of MO's WB explanation. [in my post above]
If you will read the entire link....replies also...you'll see why we agree with Igenex.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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david1097
Frequent Contributor (1K+ posts)
Member # 3662
posted
I suspect the Dr wants to see you to discuss the treatment options. HE HAS TO DO THIS TO AVOID PROBLEMS. Basically you have to be informed of the two diagnostic and treatment approaches so you can make an informed decision.
Posts: 1184 | From north america | Registered: Feb 2003
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bettyg
Unregistered
posted
quote:Originally posted by 6t5frlane:
I googled around and have found much info on bands 30 and 31 leaning towards the Positive side of Lyme testing.
Betty G you have posted a lot and are somwhat and " expert " here. What ? should I ask of the Dr.
6-5, thank you for the wonderful compliment but i'm far from an expert! I've just touched the surace of learning after 2.5+ yrs. reading on this board.
OUR good friend, TUTU, is the one i've really learned from with her posting dr. c's EXPLANATION OF WESTERN BLOT IGM/IGG blood tests.
her above link should be the same as what is in my newbie's links/advise i've sent you and thousands of others!
i need to read it better and refresh my lyme brain!
there are many experts on this board who share freely their vast knowledge from personal experience.
did you print off dr. burrascano's 05 lyme guidelines? read that again; perhaps it will answer some of your questions, and then you can discuss with YOUR LLMD next week! best wishes on getting your lyme under control 6-5!
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Michelle M
Frequent Contributor (1K+ posts)
Member # 7200
posted
quote:Originally posted by 6t5frlane: Last spring I was CDC/Igenex pos on the IGM. Here are my latest results
IGM 41IND all others Neg IGG 23-25-IND 31 +++ 34+ 30+ 39+ 41+ So Igenex Pos CDC Neg
LLMD wants to see me before decision to treat
Thoughts??
I also have 31+++, only on IgM. It's a band that shows up most reliably in late stage or entrenched lyme.
Have you been treating since last blot, or what?
I agree that the LLMD won't and shouldn't diagnose you without seeing you, no matter how many positives you have. But I bet it will be a whole 'nuther story when you do see him next week.
Keep us posted.
Michelle
Posts: 3193 | From Northern California | Registered: Apr 2005
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posted
Had 8 weeks Doxy in May......Back in 1990 was treated with 2 weeks Ceftrioxne ( spelling ? )Was diagnosed with RA instead. Have been checked several times over the years with Western Blots ..neg....July 05 new symptoms came back . Last spring I was CDC/Igenex NY Positive on the IGM
Posts: 355 | From NY | Registered: Jan 2006
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treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
you have lyme
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
quote:Originally posted by Michelle M: [QUOTE]I agree that the LLMD won't and shouldn't diagnose you without seeing you, no matter how many positives you have. But I bet it will be a whole 'nuther story when you do see him next week.
I think that's it. Let us know how it goes.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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posted
Thought I would add the Igenex tests from 2/15/06
IGM 23-25++ 39+ 41+ 66+ 93+ 34IND 93+ This is a CDC -Igenex and NY Positive IGG- All Neg except 41 IND
On 5/19/06 ( Quest ) Neg on western Blot both IGG and IGM ( no bands shown ) but positive on the "Elisa " The range there was Reactive cutoff0.163 Borderline cutoff 0.128 I was 0.259
Why the big change between last year and this year. Scared right now, I have a lot of faciculations ( muscle twitches ) especially in the calfs. I just got done doing some snowblowing and my legs are so weak I can hardly stand. I've had 3 EMG the last was July 06 Normal but worried about als and ms sice my symptoms are worse. I know many here think " LYME " causes just about everything but want an open mind. I also have a very positive RA Factor with arthritis since 1990.......Help please
Posts: 355 | From NY | Registered: Jan 2006
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posted
The best help I can give you is to tell you to get treated ASAP!! There would be nothing lost by being treated, and everything to LOSE if you don't.
Hang in there!
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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posted
Thanks Lyme too
Posts: 355 | From NY | Registered: Jan 2006
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Geneal
Frequent Contributor (5K+ posts)
Member # 10375
posted
It was possible that you are positive on the WB from Igenex and weren't positive from Quest WB because they are not known for being a lab of choice for Lyme testing.
Is it possible that Quest did such a horrible job (plus they don't test all the bands) and you have actually had Lyme?
Just a thought.
Geneal
Posts: 6250 | From Louisiana | Registered: Oct 2006
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posted
I don't think anyone replied to your first question about the ELISA because we thought you could hear the laughing from all over the world.
What I can tell you is that Lyme does not exist in Canada. This is not because we don't allow ticks to cross the border - it's because we use an ELISA to test.
The only way to get a western blot here is to have a positive ELISA first. And that just doesn't happen.
-------------------- The Canadian Lyme Disease Foundation www.canlyme.com Posts: 128 | From Canada | Registered: Sep 2006
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posted
My point was that I had a Positive Elisa test and wanted to know how reliable that was
Posts: 355 | From NY | Registered: Jan 2006
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posted
So I guess a Neg or a Pos does not mean much...at least with the Elisa. I wonder why he did it then?
Posts: 355 | From NY | Registered: Jan 2006
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posted
Is it a duck or an LLMD who ran the ELISA??? Ducks still think they are valid tests. I agree with Nancy that you can take that positive ELISA to the bank. If you're positive on an ELISA, then you probably have lyme, in my non-medical opinion.
When do you see the LLMD??
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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posted
P.S. Why take it to the bank if it's only 30% accurate????
Posts: 355 | From NY | Registered: Jan 2006
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bpeck
Frequent Contributor (1K+ posts)
Member # 3235
posted
quote: -------------------------------------------------------------------------------- Originally posted by 6t5frlane: Last spring I was CDC/Igenex pos on the IGM. Here are my latest results
IGM 41IND all others Neg IGG 23-25-IND 31 +++ 34+ 30+ 39+ 41+ So Igenex Pos CDC Neg
LLMD wants to see me before decision to treat
Thoughts??
_____________________________________________-
Assuming you have a healthy (not suppressed for any reason) immune system: IgM antibodies can spike anytime when Lyme bacteria gets out into the blood.. and if the bacteria is there for over 3 months (which is the life-span of an IgM antibody) IgG antibodies will start to be made as the IgM die out.
So.. it's my guess, that your LLMD may decide not to give you abx if you are symptom free - or are becoming symptom free... If you have symptoms, then I think he'll continue abx.
Those are my thoughts anyway. Barb
Posts: 1875 | From VT | Registered: Oct 2002
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posted
Saw Dr C in Westchester NY. Looked at all my labs since last year and going on Doxy again 3x daily for 4 weeks and see him again. He wants to treat but is not 100% convinced it's Lyme. A wait and see again. I met a woman in the waiting room IV since last year and getting better. She was Very messed up with Neuro problems and knows of a another Woman that probably will Die from Lyme. Very Sick..Scary Stuff people
Posts: 355 | From NY | Registered: Jan 2006
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posted
Man, what does it take to convince this LLMD???? I never heard of such. Oh well....as long as he treats for this "mystery illness" with Lyme specific bands.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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posted
Lyme too.....I often hear the term Lyme specific bands, Could these bands be an indicator for anything else???
Posts: 355 | From NY | Registered: Jan 2006
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quote:Originally posted by 6t5frlane: Lyme too.....I often hear the term Lyme specific bands, Could these bands be an indicator for anything else???
This band FOR SURE could be NOTHING else.....and "Lyme Specific" means JUST THAT!
39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.
Having that band alone means that you have Lyme ... in my experienced opinion.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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posted
Been on Doxy for a short time now. Man I'm dead tired and weak. A Herx ?? Mucsle twitches all over and I feel like I have the flu. ( no flu though )
Posts: 355 | From NY | Registered: Jan 2006
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posted
I don't think thyroid problems are uncommon in Lyme Disease. Sounds like a herx to me ... I get dead tired where I can hardly hold my head up. Hubby has to take over all the cooking on those days!
-------------------- sixgoofykids.blogspot.com Posts: 13449 | From Ohio | Registered: Feb 2007
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posted
Lymettoo.Thanks for the welcome to herx land. Do I get any goodies ??? Any tokens or free passes....lol
Posts: 355 | From NY | Registered: Jan 2006
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