posted
I've read some articles that say band 31 is the same as band 30. If true why does it not count on the CDC bands that matter ( I know I know ) Yes there thinking is flawed, but is band 31 really significant or not. Thought?? Going to LLMD later today
Posts: 355 | From NY | Registered: Jan 2006
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bpeck
Frequent Contributor (1K+ posts)
Member # 3235
posted
It's not flawed thinking- Yes.. 30 is thought to be the same as 31.
These 'bands' are measured by their molecular weights - so 30 would be almost indistinguishable from 31 kDa (kDa stands for kilodaltons.. a tiny weight measurement).
It's the same at the higher end of the weight scale.. 83 thru 93 kDa can't be distinguished easily either.
Michelle M
Frequent Contributor (1K+ posts)
Member # 7200
posted
"Positive test criteria is based on early Lyme disease. The CDC's criteria for a positive Western blot were developed based upon on a study of patients with early Lyme disease.[134] The serologic response of patients with late-stage Lyme disease was not analyzed and incorporated, despite that fact that such cases require a positive Western blot for diagnosis by CDC standards.
Specific markers for late-stage Lyme disease left out. Several highly specific antibody bands for Lyme (31-kDa and 34-kDa, corresponding to outer surface proteins A and B) were not included in the CDC criteria for a positive Western blot because they only appear late in the disease. These bands which have not been included on the CDC Western Blot are so specific to Borrelia Burgdorferri that they are being used/studied for the development of a Lyme Disease vaccine.[135]" [From Wikipedia on Lyme, with citations]
65, I'm SO glad you're going to see an LLMD!
Michelle
Posts: 3193 | From Northern California | Registered: Apr 2005
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