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» LymeNet Flash » Questions and Discussion » Medical Questions » anti-inflammatory effects of abx on neuro symptoms?

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Author Topic: anti-inflammatory effects of abx on neuro symptoms?
David Miller
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Member # 21583

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Met with my PCP yesterday. I described the neurological symptoms I get if I go off doxy:

brain fog
anger/irritability
memory loss
cognitive loss
aphasia
severe fatigue

He didn't believe these symptoms were caused by an active bacterial infection, that any bacteria I may have picked up along the way would be long gone after 4 months of doxy.

Instead, he suggested that it was the anti-inflammatory properties of doxy that was relieving these issues. CFS was raised as a possibility for the muscle/joint issues, and an anti-depressant for the neurological issues.

My jaw dropped. I've heard of anti-imflammatory effects of antibiotics - specifically doxycycline - but I'm stumped how that could be causing those neuro symptoms to go away - unless we're talking encephalitis. I don't think my brain is swelling and shrinking within a few days of taking/stopping doxy.

Has anyone else ever heard of this effect?

Thanks!

Posts: 98 | From Maine | Registered: Jul 2009  |  IP: Logged | Report this post to a Moderator
METALLlC BLUE
Frequent Contributor (1K+ posts)
Member # 6628

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Well that's great, but why don't "other" anti-inflammatory drugs stop the suffering? That's what I told my doctor. He looked at me like I was a retard. Even steroids don't stop it for most of us, yet the moment a cycline drug helps alleviate some of our symptoms, it's anti-inflammatory properties that get the credit?

Another interesting thing is that usually people have Herxheimer reactions about one week to two weeks on the cycline drugs. An anti-inflammatory drug doesn't do that.

A Brain SPECT scan may be in order.

--------------------
I am not a physician, so do your own research to confirm any ideas given and then speak with a health care provider you trust.

E-mail: [email protected]

Posts: 4157 | From Western Massachusetts | Registered: Dec 2004  |  IP: Logged | Report this post to a Moderator
David Miller
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Thanks MB, that's a good point.

I'm still at a loss with the basic idea of ANY anti-inflammatory agent warding off all those neuro symptoms outside of the swollen brain. Somehow I doubt the brain swells and shrinks that fast in reaction to some doxy.

Posts: 98 | From Maine | Registered: Jul 2009  |  IP: Logged | Report this post to a Moderator
METALLlC BLUE
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The medical community has made up so many excuses regarding the effects of antibiotics on Lyme Disease patients.

They deny the bacterium persists in-spite of adequate antibiotics, yet I have more than one hundred studies demonstrating otherwise. They still deny it. It's senseless and purely irrational.

--------------------
I am not a physician, so do your own research to confirm any ideas given and then speak with a health care provider you trust.

E-mail: [email protected]

Posts: 4157 | From Western Massachusetts | Registered: Dec 2004  |  IP: Logged | Report this post to a Moderator
   

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