December 20, 2010 The Obama administration issued long-awaited, long-delayed guidelines on Friday to insulate government scientific research from political meddling and to base policy decisions on solid data.
The agencies are to report to Dr. Holdren within 120 days, detailing how they will carry out the policy.
Here is a chance---Don't waste it-----
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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posted
IMO if Fox news don't like him he's our man...
There are many sites proclaiming a 30 yr. old book as their basis for refute. If you look back at what China was doing at the time,
it was commonly discussed as a possible solution by everyone.
Just don't throw out the possibilities if the President does in fact trust his judgment, just because some like Fox don't...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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onbam
Unregistered
posted
underourskin.com/blog/?p=191
Note where the NIH thug who tailed Burgdorfer said he was getting his orders from. Obama's not our man, and never was.
The left-right dichotomy in this country has become a completely false one, with the bigwigs in both parties serving the same military/banking/pharamaceutical interests. Consistently, the "liberal" and "conservative" corporate media all propagate the same core set of harmful lies.
One of the biggest foes of the Lyme community has been the NY Times, considered a very "liberal paper." (Like the Chicago Trib.)
This is something everybody needs to realize. The Lyme coverup has always been directed "from the highest levels," and has persisted through numerous administrations, both Democratic and Republican.
Making and keeping us sick is "something both parties can agree on."
The question was asked to the panelists-"How much of the funding go's to discover the cause". A--Very little.
No one on this panel could say how much went to find the causes.
But they sure as heck could tell them just how red our red SS rolls are and going to be because of the Alzheimers Epidemic.
I hated to watch, but felt I must---just to see if anyone would offer details of research for the causes...None---
Next question should be why in the heck is the energy and commerce committee deciding these important issues when they cannot even come up with a energy plan---
why should they be in charge of funding these critical medical issues?
Not to mention the division of the parties that we so gregariously fund...Enough non sense. Enough waste of our dollars. Enough already. http://republicans.energycommerce.house.gov/
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Tricky Tickey
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Hats off to Onbam for a very intelligent observation and explanation.
I give Onbam 2 thumbs up!
-------------------- Early Disseminated LD- 2010. Currently doing acupuncture and yoga. Negative Igenex (IND & Pos Bands) ISSUES AFTER: Tendonitis, letter reversal, Low immune system. PREVENTION:SaltC,Iodine,Humaworm, Chiropractic. Posts: 1013 | From In a van down by the river. | Registered: Jun 2010
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Pinelady
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posted
I disagree. It was not President Obama's watch to guard Willie...
They only let him get elected because they knew a great storm was coming and they needed someone they thought they could manipulate easily.
The financial collapse took govt.s mismanagement and turned Obama into their marionette--they thought.
They use a lot of NZ White rabbits back then to make vaccines....
Now we have UK species of borrelia showing up in CA. Which also has the highest incidence of Autism in the US. And now an Asian strain showing up in TN. No I don't know.
If you look at the schedules of cattle vaccines for those years it may not be too hard to figure out why they had to slaughter all of them. Including a lot of Zoo collections, and even got a few people..
Now we have Sweden telling us they have found the Ljungan virus can cause Both types of diabetes as well as SIDS and fetal death and deformities.
Boy that would be a hot mix...Worse than my babesia/herpes/lyme and God knows what the lesions are.
Now we have asymptomatic students testing with the new syph tests with high incidence in other countries, it is not available here, and the US saying you should consider the legal implications if you were to find a child pos. for syph....Scaring doc.'s so they won't test, and parents so they refuse to test for fear of sexual misconduct and HS taking their kids.
Dang their hides----THEY ARE ALL CROOKS.
These facts mean little until someone is in control and can sign off on funding the research needed for discoveries in all syndromes of unknown origin.
And finally get Lyme patients, and all patients of unknown origin the treatment they deserve...
Back then they just let them die, because they could not see what was happening...We don't have to let that happen anymore. We don't have time to to wait for someone everyone loves.
We just had another young man with 2 small children die Thurs. His name was J L from IL.
This has gone on for 30 yrs. now with no help.
And I don't care if its a green horse sitting as the leader of this Nation.
I'm going to keep on asking, because no one else in office seems to be able to get a bill through to do just that. He knows how I feel and everyone here has to power to do the same...
They have a new polio vaccine in the works that they say eliminated all reactions..And working on a MS vaccine when they won't event tell the public what IT is.
Don't wait too long, before they fix any chance we have at getting treatment.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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posted
Pinelady, just curious - what UK species showing up in CA and where? thx -
Posts: 13116 | From San Francisco | Registered: May 2006
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Pinelady
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http://www.ncbi.nlm.nih.gov/pubmed/21177909 2010 Dec Department of Environmental Science, Policy and Management, University of California, Berkeley, California, USA.
Abstract In North America, Lyme borreliosis (LB) is a tick-borne disease caused by infection with the spirochete Borrelia burgdorferi.
We studied the genetic diversity of LB spirochetes
... in north-coastal Californian residents.
Spirochete DNA was detected in 23.7% (27/114) of study subjects using a PCR protocol optimized for increased sensitivity in human sera.
Californians were most commonly infected with B. burgdorferi ospC genotype A, a globally widespread spirochete associated with high virulence in LB patients.
Sequence analysis of rrf-rrl and p66 loci in 11% (3/27) of PCR-positive study subjects revealed evidence of infection with an organism closely related to B. bissettii. ================= This spirochete, heretofore associated with LB only in Europe, ================= is widely distributed among ticks and wildlife in North America.
Further molecular testing of sera from residents in LB-endemic areas is warranted to enhance our understanding of the geographic distribution and frequency of occurrence of B. bissettii-like infections.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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Abstract During spring and fall 2009, 60 wild turkeys (Meleagris gallopavo) harvested by Tennessee hunters were surveyed for Borrelia spp. by
sampling their blood, tissue, ...and attached ticks. In both seasons, 70% of turkeys were infested with juvenile Amblyomma americanum;
one spring turkey hosted an adult female Ixodes brunneus.
Polymerase chain reaction assays followed by DNA sequencing indicated that 58% of the turkeys were positive for the spirochete Borrelia miyamotoi,
with tissue testing positive more frequently than blood (P = 0.015).
Sequencing of the 16S-23S rRNA intergenic spacer indicated > or = 99% similarity to previously published sequences of the North American strain of this spirochete.
Positive turkeys were present in both seasons and from all seven middle Tennessee counties sampled.
No ticks from the turkeys tested positive for any Borrelia spp. =================== This is the first report of B. miyamotoi in birds; =================== the transmission pathways and epidemiological significance of this high-prevalence spirochetal infection remain uncertain. 00000000000000000000000000 For the birds to test pos. but the ticks neg. is alarming but not suprising. It is well established that it can be very difficult to find the DNA. Esp. in early infection as exhibited in the human studies. But the fact all were neg. is very alarming.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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http://www.ncbi.nlm.nih.gov/pubmed/21183862 2010 Dec 22. Standard syphilis screening involves an initial screening with a nontreponemal test and confirmation of positives with a treponemal test. However, some laboratories have reversed the order. The Tale of Two Serologic Tests to Screen for Syph... [Sex Transm Dis. 2010] - PubMed result ----------------- http://www.ncbi.nlm.nih.gov/pubmed/21183861 2010 Dec Introduction of Rapid Tests for Large-Scale Syphilis Screening Among Female, Male, and Transgender Sex Workers in Mumbai, India. Abstract ----- You do know in Autism it is greater effected in males/testosterone. ---------------- BACKGROUND: Despite widespread availability of... rapid plasma reagin (RPR) for syphilis screening at sex worker (SW)-dedicated project clinics, uptake of syphilis testing remains low and prevalence of syphilis remains high among SWs in Maharashtra, India. The primary reasons given for refusal of RPR were fear of venipuncture and long waiting times for results.
METHODS: Between December 2007 and February 2008, rapid point of contact diagnostic tests (Syphicheck-WB, Qualpro Diagnostics, India) using finger-prick samples were introduced for syphilis screening, with RPR confirmation test of positives.
RESULTS: Uptake of syphilis screening among clinic attenders increased to 63.1% compared with an average of 14.3% before the intervention. Among the 19,809 SWs who were screened, 598 tested positive (3% prevalence of lifetime infection). Of these, 395 (66.1%) accepted RPR confirmation test; 337 (88.3%) were seroreactive, 160 (
40.5%) had titers ≥1:8 (active syphilis).
The projected overall prevalence of active syphilis among all SWs screened was 1.2% but varied by site and typology of sex work (brothel-based, 2.4%; bar-based, 0.5%; street-based, 2.3%; male SWs, 0.2%; transgender, 11.3%; home-based, 0.6%).
CONCLUSIONS: The introduction of rapid tests dramatically increased the uptake of syphilis screening in this large-scale intervention among a high-risk population in India.
However, only two-thirds of SWs with a positive rapid test accepted a confirmatory RPR test.
The high proportion (40.5%) of active syphilis among those testing positive on the rapid screening test justifies treatment even if confirmatory testing is declined. A commercially available, simple, rapid nontreponemal test is needed to further strengthen syphilis screening.----------- --------------- http://www.ncbi.nlm.nih.gov/pubmed/21150594 2011 Feb China's syphilis epidemic: epidemiology, proximate determinants of spread, and control responses. Abstract
SUMMARY: The Chinese central government recently announced a 10-year syphilis plan to provide clear expectations for evaluating the success of local syphilis control programs and integration with HIV testing programs. Further research is needed to understand the social and behavioral determinants driving the spread of syphilis. --------------- http://www.youtube.com/watch?v=2-o_8aQx4r8 ----------------- http://www.elsevier.es/revistas/ctl_servlet?_f=7264&articuloid=13187592&revistaid=103 El resurgir de la s�filis jueves, 18 nov 2010 "Syphilis is resurgent. " This powerful statement is the conclusion of numerous studies in various continentes1, 2,3,4,5,6, and is mainly explained by the increase of cases diagnosed in men who have sex with men (MSM) 7. The numbers are st...aggering: in France reported syphilis cases rose from 37 in 2000 to 428 in 2003, 96% of them men.4, 8, in the United Kingdom there were 293 in 1998 and 2,226 in 2003, again mostly at the expense of varones9, while in the U.S., the 5,979 cases in 2000 increased to 7,980 in 2004 (84% male) 10. In Spain, according to official data, in 1998 there were 772 cases while in 2008 these amounted to 2,545, which corresponds to a rise in incidence rates of 1.96 to 5.70 per 100,000 inhabitants1. That is, these figures show the incidence of syphilis in our country have tripled in the last decade1. Consistent with data from other countries, the vast majority of reported syphilis cases were men (86%), especially MSM. ----------------- No worries here..We have a vaccine coming soon that will effectively shut off your immune system so nothing infectious will be found.
This new test is picking up a lot more than they bargained for. And the US is already on the beat. --------------------- http://www.ncbi.nlm.nih.gov/pubme...d/21180630 Cyclophosphamide in multiple sclerosis: scientific rationale, history and novel treatment paradigms.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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Medical and Legal Implications of Testi...ng for Sexually Transmitted Infections in Children Margaret R. Hammerschlag1* and Christina D. Guill�n2
Divisions of Pediatric Infectious Diseases,1 Child Abuse and Advocacy, Department of Pediatrics, State University of New York Downstate Medical Center, Brooklyn, New York2
Summary: Testing for sexually transmitted infections (STIs) in children presents a number of problems for the practitioner that are not usually faced when testing adults for the same infections.
The identification of an STI in a child can have, in addition to medical implications, serious legal implications.
The presence of an STI is often used to support the presence or allegations of sexual abuse, and conversely, the identification of an STI in a child will prompt an investigation of possible abuse.
The purpose of this paper is to review the epidemiology of child sexual abuse, including the epidemiology of major STIs including Neisseria gonorrhoeae, Chlamydia trachomatis, syphilis, herpes simplex virus (HSV), Trichomonas vaginalis, and human papillomavirus, and the current recommendations for diagnostic testing in this population. --------------- They are hot on it...They don't want the new test here....And we thought they were stupid...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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Despite the continued efficacy of penicillin since the 1940s, many aspects of the natural history, diagnosis, and management of syphilis remain controversial. A key factor among the numer...ous factors explaining the persistence of significant areas of controversies is the absence of a gold standard direct method for distinguishing between the different stages of syphilis and appraising treatment response. This contribution presents an overview of some of the most debated aspects of the origins, diagnosis, and management of syphilis in immunocompetent patients. The two main current hypotheses on the origins of Treponema pallidum are the "Columbian" and the "Pre-Columbian" hypotheses. Strong evidence supports that Columbus' crew brought T pallidum to Europe at the time of discovery of the New World.
Because T pallidum culture and inoculation to animals are not readily available methods, the gold standard method for the diagnosis of syphilis is the direct identification of T pallidum by dark field microscopy or direct fluorescent antibody tests.
These methods, however, are inapplicable in many patients, and thus the diagnosis of syphilis is usually based on the clinical and serologic picture.
Serologic tests should only be considered as surrogate markers of the disease and do not provide definite distinction between syphilis stages. The optimal combination of serologic tests is still undefined. Other areas of controversy include the identification of patients who would benefit from a lumbar puncture, the diagnostic criteria of neurosyphilis, and the most relevant markers of treatment response 0000000000000000 http://www.ncbi.nlm.nih.gov/pubmed/20687840 Novel Treponema pallidum serologic tests: a paradigm shift in syphilis screening for the 21st century.
Se�a AC, White BL, Sparling PF.
Department of Medicine, University of North Carolina at Chapel... Hill, NC 27599, USA. [email protected] Abstract
The mainstay of diagnosis for Treponema pallidum infections is based on nontreponemal and treponemal serologic tests.
Many new diagnostic methods for syphilis have been developed, using specific treponemal antigens and novel formats, including rapid point-of-care tests, enzyme immunoassays, and chemiluminescence assays.
Although most of these newer tests are not yet cleared for use in the United States by the Food and Drug Administration, their performance and ease of automation have promoted their application for syphilis screening.
Both sensitive and specific, new screening tests detect antitreponemal IgM and IgG antibodies by use of wild-type or recombinant T. pallidum antigens.
However, these tests cannot distinguish between recent and remote or treated versus untreated infections.
In addition, the screening tests require confirmation with nontreponemal tests.
This use of treponemal tests for screening and nontreponemal serologic tests as confirmatory tests is a reversal of long-held practice.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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posted
Oh and Canada says if it isn't found there is no reason to look again....
Objective: To determine if repeat screening for sexually transmitted infection is appropriate for
adolescent obstetric patients
and to identify any risk factors associated with increased risk of contracting a sexually transmitted infection (STI) during pregnancy.
Methods: We conducted a retrospective review of the medical records of adolescent obstetric patients seen over a five-year period in the Young Prenatal Program at the Hospital for Sick Children (Toronto, Ontario).
Results: Between January 2003 and December 2007, 201 patients with 211 pregnancies attended the Young Prenatal Program.
Of the 211 pregnancies reviewed,
all patients had screening at baseline for HIV, syphilis, hepatitis B, chlamydia, gonorrhea, and trichomonas;
173 patients were screened in the third trimester, two were tested at another point in the pregnancy because of symptoms, and 161 were screened at their postpartum visit.
In 53 pregnancies, STI was diagnosed either during pregnancy or postpartum.
Fourteen patients had multiple sexually transmitted infections for a total of 71 infections.
Thirty-four infections were diagnosed at baseline,
15 in the third trimester, two because of symptoms,
and seven were diagnosed postpartum.
In patients who did not develop an STI during pregnancy, the previous use of contraception (excluding condoms), being in a relationship with the baby's father, and living with their partner were identified as significant protective factors against STI.
There was a trend towards significance for contracting an STI in patients with a history of abuse,
in those with a higher than average number of sexual partners,
and in those with a younger than average age of coitarche.
Conclusion: Sexually transmitted infections were diagnosed in 25.1% of adolescent pregnancies (53/211) in our cohort.
Of the 71 sexually transmitted infections diagnosed, 22.5% (16/71) were diagnosed on routine third trimester screening.
Because of the high rates of STI and the small number of identified risk factors,
routine repeat screening in the third trimester
for chlamydia, gonorrhea, and trichomonas is warranted in pregnant adolescents. -------------------- Don't worry about the bad ones....Where is the IDSA going for their annual meeting this yr.? Back to Canada I hope...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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posted
IDSA 2011 meeting is in Boston.
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Pinelady
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posted
Sorry to hear that==Here's some of the new ones coming....And for what I don't know since no one will say....
Multiple Sclerosis MS is an autoimmune diseases in which the immune system attacks the brain and spinal cord. Approximately 5 million people worldwide suffer from the disease, which causes muscle problems and a wide range of neurological iss...ues. Bayhill Therapeutics' BHT-3009 and Opexa Therapeutics' Tovaxin and both in Phase II trials. The 2020 MS vaccine market could hit $1.1 billion. ======== Parkinson's Like Alzheimer's research, drug companies have been largely unsuccessful at creating a drug to treat Parkinson's--a neurological condition caused by the the degeneration of nerve cells in the brain (neurons) that produce the neur...otransmitter dopamine. AFFiRiS is developing a Phase I vaccine for the condition, which affects up to 30 million people worldwide. ======== Alzheimer's Alzheimer's is caused by the irreversible loss of nerve cells in brain areas, leading to losses in thought, memory and language. Though a number of companies are working on an Alzheimer's vaccine, Cytos Biotechnology's Phase II C...AD106 is the most advanced. AFFiRiS, Merck, Oklahoma Medical Research Foundation and United Biomedical are all pursuing an Alzheimer's vaccine, which could have a potential market of $1.15 billion by 2020. =============== You might as well say there's at least 3 Billion that could have been spent on fixing US instead of filling their pockets...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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posted
And we're not worth a IV...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Camp Other
Unregistered
posted
Pinelady, that Borrelia miyamotoi sure gets around... Not just TN but CA, and five years ago:
J Med Entomol. 2006 Jan;43(1):120-3
Detection of a Borrelia miyamotoi sensu lato relapsing-fever group spirochete from Ixodes pacificus in California.
Mun J, Eisen RJ, Eisen L, Lane RS.
Division of Insect Biology, 201 Wellman Hall, University of California, Berkeley, CA 94720-3112, USA. [email protected]
We investigated whether host-seeking nymphs and adults of the western blacklegged tick, Ixodes pacificus Cooley & Kohls, the primary vector of Lyme disease spirochetes in far-western North America, are infected naturally with relapsing-fever group spirochetes in Mendocino County, California. Relapsing-fever group borreliae were detected in four (1.7%) of 234 nymphal and two (0.7%) of 282 adult host-seeking I. pacificus ticks by polymerase chain reaction and sequence analysis of the 16S rRNA and flagellin genes, respectively, exhibiting 99 and 98.5% sequence homology to Borrelia miyamotoi Fukunaga.
Phylogenetic analysis based on these two genes revealed that the borreliae detected in these ticks belong to the relapsing-fever group and that these are closely related to, if not identical with, B. miyamotoi.
----
And guess what our friends at Yale had to say about it?
Ho-ho...
This is from 2001. This is what they said back then:
"We report here, for the first time, the existence of a previously unrecognized Borrelia species transmitted by (Ixodes scapularis) ticks," says Durland Fish, associate professor of epidemiology in the Department of Epidemiology and Public Health at the School of Medicine and senior author of the study. "This discovery represents the fifth transmissible agent associated with this tick species in the Northeast."
[...] snipped
"Some of our experiments were getting some bizarre results," Fish says. "We were finding infected ticks in experiments where we did not expect them. We sequenced a portion of the DNA to determine what it was and it turned out to be a spirochete that is related to relapsing fever spirochetes rather than the Lyme disease spirochete."
Fish said the new organism has been found in about 2% of the nymphs tested in four states: Rhode Island; Lyme, Connecticut; Westchester County in New York; and in northern New Jersey. It was previously thought that all of the spirochetes found in deer ticks were Borrelia burgdorferi, but these findings show that up to 20% of the infected ticks are carrying this new organism instead.
[...] snipped - Are you ready for the corker? Surely. Here it is:
"It is completely cryptic, which means there is no way to diagnose it," Fish says. "None of the Lyme disease tests would detect an infection by this organism. We're anxiously studying this organism to develop diagnostic techniques and to determine whether or not it infects people. If it does, it's likely that the same treatment for Lyme disease would be effective against this organism."
How much do you want to make a bet the ton of us who are seronegative for Lyme would be positive for this organism if the tests included the miyamotoi genotype?
Seriously.
This is something Dr. L (who spoke at the IOM, not an LLMD) should do with his ongoing research on the Borrelia genome: help with development of tests which pick up these genotypes.
This is INSANE.
From now on, if you have all the symptoms of Lyme Disease but it acts like Relapsing Fever and your tests are negative? Don't say it's seronegative Lyme. May be better to say, "I have Miyamotoi Disease".
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Of course. It's never that simple.
"Although how B. miyamotoi and B. davisii affect the health of humans and other animals remain to be determined, our finding of 3 Borrelia species with overlapping life cycles in the same host in the same area shows that the ecology of Borrelia is more complex than was imagined. The presence of species other than B. burgdorferi in a major reservoir will have to be considered in future surveys and interventions." --Third Borrelia Species found in White-footed Mice: http://www.cdc.gov/ncidod/EID/vol11no07/04-1355.htm
It is suspected miyamotoi can produce a Lyme-like or more like relapsing-fever-like illness in humans, but it is not proven yet.
So. We need more research. Yesterday.
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Pinelady
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posted
Great Posts. I had not seen that. Somebunnies need to go to jail when human lives are caused by arrogance and greed.
I still believe the only difference in the species is what is melded within the folds.
Where they say n can be anything that is exactly what it means...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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posted
I've read all the posts. The blame, the facts, the difference of opinion. No one know better the hell a Chronic Lyme patient goes through then us. Putting all of the BS politics aside, what can WE do to make a difference NOW?
-------------------- TLH Director Posts: 2 | From NJ | Registered: Jan 2011
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Pinelady
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posted
Got Lyme in China! I am putting this here because up above I spoke of China/etc.'s syphilis reemergence. I am not sure which test they used.
Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China. Abstract
OBJECTIVE: To describe the epidemiologic characteristics
and clinical manifestations
of 59 persons recruited via an internet chat group who complained of
AIDS-like symptoms, so as to formulate effective intervention strategies and measures.
METHODS: Case was defined as onset of any three of the following self-reported AIDS-like symptoms in a member of relevant "internet chat groups":
persistent low grade fever, rash, swollen lymph node, fatigue, diarrhea, weight loss and low CD4(+)T count.
We administered an internet-based questionnaire, and
invited 59 of the 88 case-persons for voluntary physical examination and laboratory testing.
RESULTS: The 59 case-persons came from 22 provinces; 54 (91.5%) were men; the median age was 34 (range: 22 - 53) years; 84.7% of them had high-risk sexual behaviors before the onset of self-reported symptoms.
The median time interval from exposure to onset was 15 d (range: 1 - 365 d).
Blood specimens for all the 59 case-persons were tested negative for HIV and syphilis antibodies.
There was also no evidence of Xenotropic murine leukemia virus-related virus infection.
One case-person was tested positive for hepatitis C virus antibody.
The average CD4(+)T lymphocyte count was 707/�l.
Of the 59 case-persons,
57 (96.6%) sought medical care from multiple providers;
40 were diagnosed to have no physical disorders.
CONCLUSION: None of the 59 case-persons had any evidence of infection with HIV or any other infectious agents that could explain their self-reported symptoms. ---------------
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
TLH I would like to see the people organize nationally.
With committees designated to the cause for which they are assembled.
Soon I envision all Lyme patients being able to get care-just like AIDS patients and they are organized just so.
There would be no more indecisiveness which has led to ineffectiveness. It is voted and approved by the patients themselves as it should be since it will be in their interest.
I hope we can all come together to write bills we all approve. I hope we can all come together on leadership. I hope we can all come together on assembly. And I hope we can come together on any dissemination of funds which is so vital.
If we cannot come together now I fear this will not be possible in the near future.
This is not about just US that needs to know it is about the world, but we have a chance to lead, and show them how tough we are. All of them.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
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Member # 18524
posted
By the way China last mth. during economic trade talks was asked to allow beef trade. They said they would consider it. A polite way of bowing---out.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Camp Other
Unregistered
posted
Fund microbiology researchers to do confirmatory research of persistence on a large scale. Make sure their research gets in the media directly and not through a gateway PR rep at the IDSA and other organizations.
Basically, the truth has to go from source to world without stopping for a quick filter fitting.
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onbam
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posted
Pinelady--apparently, Wormser's a major figure in AIDS too. I assume that they're getting the federal shaft just like us. Also, we'll see how much anyone wants our beef when they move plum Island to Manhattan, Kansas. "Oops, did we forget to tell you there's no way to test for mad cow?" :
Camp--this is precisely the problem. There are people behind the IDSA, which is merely acting as a mouthpiece. Steere, Wormser, et al. are being told what to do by someone and apparently, that someone sits "at the highest levels" of power.
filedropper.com/lymeshow goes into this.
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posted
Onbam, money for the CDC and IDSA is getting cut this year and shifted to the NIH budget. Follow the money. I suspect anything the gov't really wants worked on will be worked on there, partisan issues having not a thing to do with it. It's all about money.
And yes, I think that the Kansas facility is a bad idea. Bad location. Poor isolation. And more. Plum Island, sordid history that it has - actually a better place for research.
The US already isn't really testing for mad cow. I'm rarely eating beef in this country. I think Australian and Japanese beef are required to go through screenings our beef is not. I consider beef a treat at this point.
Burgdorfer did speak, though. And there are others. If they come forward and speak to the media - including the foreign researchers who are aware of this issue - then some things can shift. A little bit of credible scientific dissent means something.
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Pinelady
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Member # 18524
2010 I consider this overdone, and robbing the public in broad daylight.
This review summarizes how mitochondrial pathobiology might contribute to neuronal death in AD, PD, and ALS and could serve as a target for drug therapy. ============= Instead of giving them the IV antibiotics to cure these guys make them guinea pigs...Which is worse?
Botulinum toxin A versus B in sialorrhea: A prospective, randomized, double-blind, crossover pil...ot s
tudy in patients with amyotrophic lateral sclerosis or Parkinson's disease. ================= http://www.lunduniversity.lu.se/o.o.i.s?news_item=5467&id=24890 Unfolding pathogenesis in Parkinson's - Breakthrough suggests damaged proteins travel between cells 19 January 2011 ----------------- http://www.ncbi.nlm.nih.gov/pubmed/21261515 2011 Jan Amyotroph Lateral Scler. 2011 Jan 24. [Epub ahead of print] Identification of novel FUS mutations in sporadic cases of amyotrophic lateral sclerosis.
These guys don't know what they are seeing---All the variance is all the different organisms in there hiding..... Just like in Borrelia--the only difference in the species is what all it is packing.... --------------------- IMO they know exactly what they are doing. They are intent on keeping up sick...But the cat is out of the bag... ======================= http://www.ncbi.nlm.nih.gov/pubmed/21264474 J Neurol. 2011 Jan 25. [Epub ahead of print] Migration and multiple sclerosis in immigrants to Australia from United Kingdom and Ireland: a reassessment. I. Risk of MS by age at immigration.
Jumping on the bandwagon quick==AU still says they don't have Borrelia---McD's gets most of their beef from AU...Not to mention they were members of the countries that were advising on the tick vaccine for cattle.
So while they may be losing profits--they still intend to keep control. ------------------ In conclusion, B. burgdorferi EbfC possesses both sequence-specific and sequence-independent DNA binding activities. Genes orthologous to ebfC are found in the genomes of a broad range of bacterial species, and the orthologs of E. coli and ...H. influenzae are also DNA-binding proteins (Cooley,A.E. et al., submitted for publiction).
Thus, characterization of B. burgdorferi EbfC impacts upon the entire kingdom Eubacteria. It also appears that EbfC family members interact with DNA through a unique fold, and represent a novel type of DNA-binding protein. http://nar.oxfordjournals.org/content/37/6/1973.full#SEC5
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
Is it possible they are trying to prevent panic...
However there is nothing to panic about--The damage is done.
Just give us a chance and treat the dang stuff.. Stop denying we are really sick---because we are REALLY SICK.
We know we have many going to India getting stem cells and getting well...
And we have many things we could be doing if they would come clean so our doctors are free to prescribe at will things that the patients need.
So many things they could be doing to help people through his hell.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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