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» LymeNet Flash » Questions and Discussion » Medical Questions » WB Test results -- 19 yrs with MS

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Author Topic: WB Test results -- 19 yrs with MS
tory2457
LymeNet Contributor
Member # 10384

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Hi everyone,
I posted on the General section stating I'm a new patient of Dr P in CT and today was my first day of antibiotics; Lymetoo asked which band was positive: here they are

IgM
**23-25
**31 IND
**34
**39
**41 IND
**83-93

IgG
**23-25
30 +
**31 IND
**34 IND
**39
**41 ++
58 ++
**83-93

Also my CD57 is 21
If anyone can explain what CD57 is I'd appreciate the help.

Glad to be a part of this community!
tory2457

Posts: 158 | From PA | Registered: Oct 2006  |  IP: Logged | Report this post to a Moderator
Sammi
Frequent Contributor (1K+ posts)
Member # 110

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Hi tory2457. Below is the breakdown of the Western Blot:

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

Band 41 is often the first to show and yours is positive. Bands 31 and 34 are Lyme specific bands. Yours are IND. I think this is signifcant.

Your CD-57 is very low which I believe is also indicative of Lyme disease. You can read about it in Dr. Burrascano's treatment guidelines on page 8 at http://www.ilads.org/burrascano_0905.html

I am glad you are seeing Dr. P. Were you tested for the co-infections? Which meds are you taking?

Good luck with your treatment!

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Lymetoo
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Member # 743

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Sammi gave you the lowdown...here's more:

Western Blot explanation:
http://tinyurl.com/ffn3x

From the above link:
"The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93."

Also read what the dr wrote about the "IND" and why it can also be of significance.

Sammi...what is the source of your information? I'd like to document it on Dr C's WB thread.

Welcome to our little world, Tory!! [Smile]

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96239 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
bettyg
Unregistered


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Tory, did you get my 19 pages of newbie links/advise? If not, private message, PM, me using the 2 people standing together on my post to you here. Thanks so much.

WELCOME! Bettyg [Big Grin]

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tory2457
LymeNet Contributor
Member # 10384

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Thank you all for these remarkable responses! I will do my best in answering your questions, but I find myself behind in Lyme knowledge since my focus was obviously on CRABS.
(I am reading as fast as I can)

Sammi--regarding the co-infections
Bartonella - Negative
Babesia - Negative
I'm told these tests aren't that reliable

Chlamydia pneumoniae IgG 1:256
Ciq binding: 14.3

Meds:
200mg Doxy -daily for 2wks increasing if tolerated...I really do appreciate starting slow
Again, if I didn't answer what you were looking for pls let me know.

Lymetoo:
thanks for the link and advise

bettyg:
I did find the link/Newbie and it's great! Thanks

I am going to pm you regarding someone I'm helping from a MS site..Since I'm such a newbie would you mind giving her the correct "basic" info? I'm sending her things to read like "Unraveling the Mystery of Misdiagnosis" but would appreciate any help..

I'm so thrilled to finally be here and on the right path to feeling better---
It's amazing how comfortable I feel when logging on!

[Big Grin] [Big Grin] [Wink]

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Michelle M
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Member # 7200

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Welcome Tory!

You'll be in good company -- many of us here were in the 'misdiagnosed as MS' category prior to investigating for lyme. And sadly, it usually wasn't our doctors to give us a clue!

Ask lots of questions and don't be shy.

Just for fun, do a search for the thread "Are all neurologists goofy?" Perhaps it will bring a smile to your face!

Michelle

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Michelle M
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Member # 7200

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Never mind - you're new to searching! I couldn't resist dragging it out myself. Here it is -- enjoy!:

Are All Neurologists Goofy???

Michelle

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Lymetoo
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Member # 743

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I love Wild Condor's site because it's so organized. Not so overwhelming for newbies, but TONS of info.

Wild Condor's Links and information:
http://www.wildcondor.com/lymelinks.html

Glad you found us, Tory!

 -

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96239 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
   

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