This is topic If you don't tolerate well one macrolid, will you tolerate well others? in forum Medical Questions at LymeNet Flash.


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Posted by Areneli (Member # 6740) on :
 
My liver enzyme went quite high after Ketek (that is similar to macrolides).

Does it mean that I will have the same problems with Zithro, biaxin and other macrolids?

[ 15. March 2006, 07:36 PM: Message edited by: Areneli ]
 
Posted by duramater (Member # 6480) on :
 
I don't tolerate Biaxin at all (think Mt Vesuvius) whereas I'm doing just dandy with Zithromax suspension. Of course, your mileage may vary...

Same deal for me with the teteracyclines. Doxy turns me into a bucket of misery (belly hurts and crushing fatigue). Minocycline and I get along no problem. Go figure. Maybe the pharmacy is giving me placebos in place of the mino capsules!
 
Posted by TheCrimeOfLyme (Member # 4019) on :
 
Not necessarilly.

Ketek is CLOSE to a macrolide, about as close as you can get.
Biaxin and Zithromax are only ONE molecule apart.

I have a sensitivity to both zithromax and biaxin though. Ketek didn't phase me much.
 
Posted by JeffM (Member # 8919) on :
 
My LLMD took me off Ketek when there was word of liver failure in three people in January.

Too bad, because another LLMD told me that recent research has demonstrated a lot of efficacy for ketek.
 
Posted by tempe (Member # 5000) on :
 
I had liver pain on ketek at beginning of February, so went off.

Went on to biaxin, and again had liver pain plus dark urine & now my skin has yellowed.

I never used to have trouble with biaxin. But ketek may have damaged the P450 enzyme pathway, and my dr says now I shouldn't take any in the same class because they use the same pathway.
 
Posted by firecop1066 (Member # 6920) on :
 
Biaxin was a wonder drug for me with no side effects....

Zithromax almost landed me in the ER with abdominal distress crampings....

I love clindymiacin....

so i think its just trial and error, i dont think its the same just because the drugs are in the same class...IMO....Jill
 
Posted by Areneli (Member # 6740) on :
 
Hey firecop1066,

What doses of Clindamicin did you use?
 
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