LymeNet Flash: If you don't tolerate well one macrolid, will you tolerate well others?

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»	LymeNet Flash » Questions and Discussion » Medical Questions » If you don't tolerate well one macrolid, will you tolerate well others?

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Topic: If you don't tolerate well one macrolid, will you tolerate well others?

Areneli
Frequent Contributor (1K+ posts)
Member # 6740

posted

My liver enzyme went quite high after Ketek (that is similar to macrolides).

Does it mean that I will have the same problems with Zithro, biaxin and other macrolids?

[ 15. March 2006, 07:36 PM: Message edited by: Areneli ]

Posts: 1538 | From Planet Earth | Registered: Jan 2005 | IP: Logged |

duramater
LymeNet Contributor
Member # 6480

posted

I don't tolerate Biaxin at all (think Mt Vesuvius) whereas I'm doing just dandy with Zithromax suspension. Of course, your mileage may vary...

Same deal for me with the teteracyclines. Doxy turns me into a bucket of misery (belly hurts and crushing fatigue). Minocycline and I get along no problem. Go figure. Maybe the pharmacy is giving me placebos in place of the mino capsules!

Posts: 689 | From western MA (we say buttER and pizzA) | Registered: Nov 2004 | IP: Logged |

TheCrimeOfLyme
Frequent Contributor (1K+ posts)
Member # 4019

posted

Not necessarilly.

Ketek is CLOSE to a macrolide, about as close as you can get.
Biaxin and Zithromax are only ONE molecule apart.

I have a sensitivity to both zithromax and biaxin though. Ketek didn't phase me much.

--------------------
You want your life back? Take it.

Posts: 3169 | From Greensburg, Pennsylvania | Registered: Jun 2003 | IP: Logged |

Getting Better
LymeNet Contributor
Member # 8919

posted

My LLMD took me off Ketek when there was word of liver failure in three people in January.

Too bad, because another LLMD told me that recent research has demonstrated a lot of efficacy for ketek.

--------------------
Jeff

Posts: 533 | From CA | Registered: Mar 2006 | IP: Logged |

tempe
LymeNet Contributor
Member # 5000

posted

I had liver pain on ketek at beginning of February, so went off.

Went on to biaxin, and again had liver pain plus dark urine & now my skin has yellowed.

I never used to have trouble with biaxin. But ketek may have damaged the P450 enzyme pathway, and my dr says now I shouldn't take any in the same class because they use the same pathway.

Posts: 172 | Registered: Dec 2003 | IP: Logged |

firecop1066
Member
Member # 6920

posted

Biaxin was a wonder drug for me with no side effects....

Zithromax almost landed me in the ER with abdominal distress crampings....

I love clindymiacin....

so i think its just trial and error, i dont think its the same just because the drugs are in the same class...IMO....Jill

Posts: 83 | From Northern Illinois | Registered: Feb 2005 | IP: Logged |

Areneli
Frequent Contributor (1K+ posts)
Member # 6740

posted

Hey firecop1066,

What doses of Clindamicin did you use?

Posts: 1538 | From Planet Earth | Registered: Jan 2005 | IP: Logged |

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