This is topic seroconversion after antibiotic treatment? in forum Medical Questions at LymeNet Flash.


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Posted by grace1 (Member # 10347) on :
 
i've read about people who were seronegative turning seropositive transiently after getting treatment.

does anyone know, is there a timeline when this happens? like is it most likely to occur X number of weeks after starting antibiotics, or does it occur after stopping treatment?

and how transient is this, and why is it transient?
 
Posted by Lymetoo (Member # 743) on :
 
Doesn't Dr C address that in his WB explanation? Check below.

I think you can get retested after 3-4 wks on abx. And it's probably better to go off two wks before the test.

Western Blot explanation:
http://tinyurl.com/ffn3x
 
Posted by Lymetoo (Member # 743) on :
 
quote:
Originally posted by MRB:
I wonder if, for a person who is already positive (by Igenex standards), if a second western blot would come out "more positive" (wow...what horrendous grammar) after 6 weeks of oral antibiotics.


I had a second WB about 5 wks after the first. Went off abx for the two wks before the test.

It went from showing 2 bands to showing 7!! Even though it still wasn't CDC positive, I figured nothing else could have made those Lyme bands show up!

Since I'd had it for so many years prior to testing, I know my less than positive result was due to my suppressed immune system.
 
Posted by trueblue (Member # 7348) on :
 
I think I was like Tutu, in that, I had been sick for so many years my body really wasn't making antibodies by the time I was finally tested.


13 years ago, I was diagnosed clinically with just band 34 on an IgG.

WBs were taken while on treament, every 3-6 months, and each time another band or so would appear.

It took almost 3 years to get a fully positive test.


Nowadays I generally come up with a smattering of + bands and a bunch of INDs, moreso on IgM than IgG. I never had an IgM response before last year. [confused] (This last one was done while not on ABX.)
 
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