This is topic Western Blot results - need help understanding - from Lab Corp. in forum Medical Questions at LymeNet Flash.


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Posted by fedup (Member # 11837) on :
 
Can someone plese help me understand what these tests results mean. Here is part of the lab test results from Lab Corp.

Lyme AB IGG by WB
P41 Ab. - Present

Lyme Ab IgM by WB
p41 Ab. - present
P39 Ab. - Present

Lyme IgM WB Interp. - POS
Lyme IgG/IgM Ab - <0.91 Index 0.00 - o.90
 
Posted by Lymetoo (Member # 743) on :
 
Wow! Take it to the bank!! Band 39 is specific for Lyme. End of story!

Welcome to our little family! Now you can begin your journey toward restoring your health!

Western Blot explanation:
http://tinyurl.com/ffn3x

from the above link:

"39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all."
 
Posted by Lymetoo (Member # 743) on :
 
quote:
Originally posted by fedup:

Lyme IgG/IgM Ab - <0.91 Index 0.00 - o.90

Is this the ELISA???
 
Posted by Soleilpie (Member # 8481) on :
 
It clearly shows that your IgM is CDC positive for Lyme.

This would more or less be considered an active infection by most mainstream doctors.

IgM is the antibody that initially responds to an infection and then later IgG takes over.

Your IgG is CDC negative and I would assume negative even through Igenex.

I'm not sure about the ELISA (IgM/IgG). Is that the index for a negative? Generally, anything greater than a 1.0 is a positive. Your results may actually be equivocal.

At any rate, it appears that you're positive for Lyme disease. I'm really sorry about that.

When band 39 pops up, that should be a red flag. From my research, it's the one band that shows a current infection.

Apparently, band 39 only show up when the spirochetes are alive (versus dead).

Also, it's specific ONLY to Borrelia burgdorferi.
 
Posted by Lymetoo (Member # 743) on :
 
from the above link:

"With most infections, your immune system first forms IgM antibodies, then in about 2 to 4 weeks, you see IgG antibodies. In some infections, IgG antibodies may be detectable for years.

Because Borrelia burgdorferi is a chronic persistent infection that may last for decades, you would think patients with chronic symptoms would have positive IgG Western blots.

But actually, more IgM blots are positive in chronic borreliosis than IgG. Every time Borrelia burgdorferi reproduces itself, it may stimulate the immune system to form new IgM antibodies.

Some patients have both IgG and IgM blots positive. But if either the IgG or IgM blot is positive, overall it is a positive result.


Response to antibiotics is the same if either is positive, or both. Some antibodies against the borrelia are given more significance if they are IgG versus IgM, or vice versa."
 
Posted by map1131 (Member # 2022) on :
 
Lab Corp found lyme band??? Oh my. Didn't know they would recognize it.

Pam
 
Posted by Geneal (Member # 10375) on :
 
Actually, my neighbor was IgM CDC positive for lab corp.

Scary isn't it????!!!

Hugs,

Geneal
 
Posted by elle108 (Member # 11730) on :
 
My daughter was also IgM positive at Lab Corp...


our LLMD, a very quiet man, simply held up the test and said, "you are very lucky to have gotten this from this particular lab...
 


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