This is topic Need help with igenex results!! in forum Medical Questions at LymeNet Flash.


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Posted by randibear (Member # 11290) on :
 
i just got back from d's house. she has lyme. she showed me her igenex and she had 3 or 4 starts at practically every category!! i mean, i've never seen so many. when she saw mine, she said, "i've never seen one so low..."

so here are my results! can you telll me what ya think please?

IGG results

18 kd -- negative
22 kda -- negatve
**23-25 -- IND
28 kda -- negative
30 kda -- negative
** 31 kda -- IND
** 34 kda -- negative
37 -- negative
** 39 kda -- +
** 41 kda -- +
45 kda -- negative
58 kda -- negative
66 kda -- negative
73 kda --negative
83 kda -- negative
** 93 kda -- negative

IGM results

everything negative except for ** 41 kda which was +

babs and erck were negative also.

she couldn't believe my ratings but there they are.
 

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Posted by Geneal (Member # 10375) on :
 
Dear Randibear,

I have to remind myself, as I only had one positive band via Quest (IgM 23)

That more bands does not mean a higher bacteria load.

Less bands, according to my LLMD, often means you are one sick puppy.

The bands are indicative of your body's immune response to Lyme.

Your daughter's body is jumping to the occasion, while yours is kind of on vaction.

In my very humble opinion, you have Lyme.

Hugs,

Geneal
 

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Posted by Lymetoo (Member # 743) on :
 
Western Blot explanation:
http://tinyurl.com/ffn3x

From the above link:

"Many would say the " +/-" equivocal ["IND"] bands are not significant. The problem I have with that, is that there are "-" negative bands. The lab has no trouble calling some bands negative. So they must be seeing something when they put "+/-" at some bands.

The only thing that makes sense, is that there is a little bit of that antibody present in your serum. If the "+/-" equivocal is reported on the borrelia associated bands, it is usually significant, in my clinical experience. This is a strong clue that I am on the right track."

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23-25: Outer surface protein C (osp C).

31: Outer surface protein A (osp A). 34: Outer surface protein B (osp B).

39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.

41: Flagella or tail. This is how Borrelia burgdorferi moves around, by moving the flagella. Many bacteria have flagella. This is the most common borreliosis antibody.

"The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93."

----written by Dr C of MO

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If you had ONLY band 39 as positive, it would mean you'd have to have Lyme. Nothing else can make that band show positive!

[ 27. September 2007, 11:32 PM: Message edited by: Lymetoo ]
 

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Posted by TickTock4422 (Member # 12553) on :
 
Helo,

There are specific bands that are indicative specifically for the Lyme bacteria; Band 41 is the most important for Lyme being positive and yours is positive. 23-25, also important bands, are "indeterminate," meaning they are read as faint positive, so IS considered positive. The band is seen, so is considered present.

As I was told over and over, if you did not have Lyme, these specific bands would not be positive.

Tick Tock
 

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Posted by Lymetoo (Member # 743) on :
 
^^
 

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Posted by Lymetoo (Member # 743) on :
 
^^
 

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Posted by barksplinter (Member # 13249) on :
 
My IgenX IgM Western Blot this summer had 8 +, 2++, and 1 IND. I have issues but I am not NEARLY as sick as my wife. Variables are:
1. She has Babeisia.
2. I continuously work around sick people.. my imunue system is continuously fired up.


That being said, had my first visit with a supposed LLMD yesterday. Did a dance around my IgM not being positive on 23-25....need more testing! He happens to own a lab.
 

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Posted by lucecaboose (Member # 13058) on :
 
Yours and mine are similar:

IGG, 41+
IGM, 30++, 31-IND, 58+

It may be a negative result, but you have Lyme.
 

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Posted by Grady (Member # 12875) on :
 
My results:
POSITIVE: 2 of the following bands: 23, 39 or 41

I took the IgeneX test a couple years ago. If I take it again, is there a chance it would show different results?
 

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Posted by CherylSue (Member # 13077) on :
 
My Igenex results came back this week. I'm negative on the IgM, but positive on the IgG. What significance does this have? I assume I do have Lyme, but an old infection? I had +++ on 41 for the IgG and + 23-25. 31 & 39 were IND.

CherylSue
 

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Posted by Lymetoo (Member # 743) on :
 

quote:

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Originally posted by Grady:
My results:
POSITIVE: 2 of the following bands: 23, 39 or 41

I took the IgeneX test a couple years ago. If I take it again, is there a chance it would show different results?

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quote:

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Originally posted by CherylSue:
My Igenex results came back this week. I'm negative on the IgM, but positive on the IgG. What significance does this have? I assume I do have Lyme, but an old infection? I had +++ on 41 for the IgG and + 23-25. 31 & 39 were IND.

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