Bartonella (Rochalimaea) henselae is a cause of peliosis hepatis and bacillary angiomatosis, and one of the putative agents of cat scratch disease. Specific therapy for B. henselae infections is not available.
Treatment failures and relapses are frequent, especially following brief antibiotic courses, and this contrasts with the in-vitro susceptibility of B.henselaeto most antibiotics.
We decided to test the antibiotic susceptibility of B.henselae associated with murine macrophage-like cells (P388 D1) and a human endothelial cell line.
We carried out a bactericidal assay in this model and in axenic broth. In both models, only aminoglycosides were bactericidal.
These results suggest that aminoglycosides may be effective in the treatment of B. henselae infections.
Posted by swedish lyme sufferer (Member # 14579) on :
Hi, I think I will try gentamicin, which belong to this group I believe. Dr. B says in his lecture on BLO that this medication might work! So will see, I come back!
Posted by savebabe (Member # 9847) on :
I believe this type of abx has to be taken IM or IV.
I am seeing my llmd on tues and I am going to ask about the IM version..
Feel better VL Posted by stormton (Member # 14412) on :
I would keep the aminoglycosides as a last resort option against bartonella. There is too much risk with hearing/equilibrium damage.
I would try the following which are much safer. Rifampin, Bactrim, Zithromax, Biaxin high dose 2000mg, Minocycline or even ketek.
Levaquin and cipro can be risky too.
If you must resort to streptomycin or gentamicin then I recommend looking into alpha lipoic acid(super antioxidant) supplementation to possibly prevent hearing damage. Alpha lipoic acid has been used before to possibly fend off this side effect. Try reading up on it.
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