This is topic Cysteine's Negative effects.... in forum Medical Questions at LymeNet Flash.


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Posted by pingpong (Member # 13706) on :
 
according to the abstract below, consider if cysteine may be causing some bleeding.

Title: Hemolytic activity of Borrelia burgdorferi.
Authors: Williams LR, Austin FE
Source: Infect Immun 1992 Aug;60(8):3224-30
Organization: Department of Microbiology and Immunology School of Medicine University of Louisville Kentucky 40292.

Abstract:
Zones of beta-hemolysis occurred around colonies of Borrelia burgdorferi grown on Barbour-Stoenner-Kelly medium containing agarose and horse blood. Blood plates were inoculated with either the infective strain Sh-2-82 or noninfective strain B-31 in an overlay and incubated in a candle jar. Both strains of B. burgdorferi displayed beta-hemolysis after 1 to 2 weeks of incubation. The hemolytic activity diffused out from the borrelial colonies, eventually resulting in lysis of the entire blood plate. Hemolysis was most pronounced with horse blood and was less intense with bovine, sheep, and rabbit blood. Hemolysis was enhanced by hot-cold incubation, which is typical of phospholipase-like activities in other bacteria. Further characterization of the borrelial hemolysin by using a spectrophotometric assay revealed its presence in the supernatant fluids of stationary-phase cultures. Detection of the borrelial hemolytic activity was dependent on activation of the hemolysin by the reducing agent cysteine . This study provides the first evidence of hemolytic activity associated with B. burgdorferi.
Keywords:
Animal, Borrelia burgdorferi, PY, Cysteine, PD, Hemolysins, BI, Hemolysis, Horses, Human, Lyme Disease, BL, Support, Non-U.S. Gov't, Temperature, Medline File

Language: German

Unique ID: 92347995
 
Posted by lou (Member # 81) on :
 
Hmmm, does that mean I should stop taking NAC?
 
Posted by cottonbrain (Member # 13769) on :
 
i take NAC too.

can someone please break up or explain this article? my tiny brain can't get it.
 
Posted by pingpong (Member # 13706) on :
 
up for further discussion
 
Posted by Lymen (Member # 6882) on :
 
NAC is not cysteine

Cysteine is known to be toxic so nothing surprising here.
 
Posted by pingpong (Member # 13706) on :
 
I thought the same about nac. tis is just acetic acid hooked up to cycsteine.
this could mean it may just take a little longer to have the same hemolytic effect as cysteine, since its just a matter of the body first removing the acetic acid from the cysteine, leaving cysteine as such.
 
Posted by pingpong (Member # 13706) on :
 
up for further discussion
 
Posted by creativeguy (Member # 15046) on :
 
Yeah, but what does the article really mean though?... If someone could say what it does in respect to lyme. I'd like to find this out.
Thanks,
Rob
 
Posted by pingpong (Member # 13706) on :
 
up for further discussion
 
Posted by pingpong (Member # 13706) on :
 
up for further discussion
 
Posted by pingpong (Member # 13706) on :
 
up for further disc.
 


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