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» LymeNet Flash » Questions and Discussion » Medical Questions » Cysteine's Negative effects....

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Author Topic: Cysteine's Negative effects....
pingpong
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according to the abstract below, consider if cysteine may be causing some bleeding.

Title: Hemolytic activity of Borrelia burgdorferi.
Authors: Williams LR, Austin FE
Source: Infect Immun 1992 Aug;60(8):3224-30
Organization: Department of Microbiology and Immunology School of Medicine University of Louisville Kentucky 40292.

Abstract:
Zones of beta-hemolysis occurred around colonies of Borrelia burgdorferi grown on Barbour-Stoenner-Kelly medium containing agarose and horse blood. Blood plates were inoculated with either the infective strain Sh-2-82 or noninfective strain B-31 in an overlay and incubated in a candle jar. Both strains of B. burgdorferi displayed beta-hemolysis after 1 to 2 weeks of incubation. The hemolytic activity diffused out from the borrelial colonies, eventually resulting in lysis of the entire blood plate. Hemolysis was most pronounced with horse blood and was less intense with bovine, sheep, and rabbit blood. Hemolysis was enhanced by hot-cold incubation, which is typical of phospholipase-like activities in other bacteria. Further characterization of the borrelial hemolysin by using a spectrophotometric assay revealed its presence in the supernatant fluids of stationary-phase cultures. Detection of the borrelial hemolytic activity was dependent on activation of the hemolysin by the reducing agent cysteine . This study provides the first evidence of hemolytic activity associated with B. burgdorferi.
Keywords:
Animal, Borrelia burgdorferi, PY, Cysteine, PD, Hemolysins, BI, Hemolysis, Horses, Human, Lyme Disease, BL, Support, Non-U.S. Gov't, Temperature, Medline File

Language: German

Unique ID: 92347995

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pingpong

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lou
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Hmmm, does that mean I should stop taking NAC?
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cottonbrain
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i take NAC too.

can someone please break up or explain this article? my tiny brain can't get it.

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pingpong
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up for further discussion

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pingpong

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Lymen
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NAC is not cysteine

Cysteine is known to be toxic so nothing surprising here.

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pingpong
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I thought the same about nac. tis is just acetic acid hooked up to cycsteine.
this could mean it may just take a little longer to have the same hemolytic effect as cysteine, since its just a matter of the body first removing the acetic acid from the cysteine, leaving cysteine as such.

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pingpong

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pingpong
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up for further discussion

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pingpong

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creativeguy
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Yeah, but what does the article really mean though?... If someone could say what it does in respect to lyme. I'd like to find this out.
Thanks,
Rob

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"Soylent Green is lymies!!"
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pingpong
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up for further discussion

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pingpong

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pingpong
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up for further discussion

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pingpong

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pingpong
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up for further disc.

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pingpong

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