I need input from those of you who have pulsed flagyl.
I took 2 pills per day (250 mg, I believe) for 2 weeks. I actually had a few good days, and several bad days during this time.
I also take doxy & ceftin every day (not pulsing). I'm just now starting my two weeks "off" flagyl, and feeling horrible.
Is this normal? Do you feel better while taking flagyl, or off? I've experienced headaches and all kinds of pains, but I want to stick with it.
Thanks in advance.
Posted by Jeff S. (Member # 21361) on :
TX
I recently pulsed Flagyl for the first time. I did it for 9 weeks,1500 mg per day.
I was 3 days on and 4 days off initially and then 4 days on and 3 days off. At the same time, I maintained my doxy dose (full time) at 400 mg per day.
So your dose is relatively smaller.
I had a very similar experience to yours. I had periods when I felt worse and symptoms were amplified. I think this is normal and probably good.
As long as you can deal with it, push through to the end of the regime.
I have been off flagyl for over 2 weeks now and I am feeling better than before I started.
Hang in there and good luck!
Posted by Pinelady (Member # 18524) on :
I am on Flagyl. I developed severe shoulder pain and since starting 600 vitamin E it is helping. Hang in there.
Posted by WildCondor (Member # 434) on :
Pulsed Flagyl was great! I did 3,000 mg/day for 2 weeks on then 2 weeks off. In the beginning I took 1,500 mg per day for 2 months straight, then went to pulsing. It was always combined with other antibiotics such as 1,200 mg Zithromax, 1.2 MU Bicillin LA 4x per week Flagyl was truly a breakthrough for me. The herxing was intense, it did make me feel gloomy, but it was all worth it in the end. Posted by txgirl09 (Member # 21612) on :
Wow, those are high doses!
Did you feel any different on your "off" weeks? I guess I'm also confused because today is my second day off flagyl, and I'm feeling worse than ever!
Thanks, I'm glad to hear you have all had such success with it.
[ 10-29-2009, 05:24 PM: Message edited by: txgirl09 ]
Posted by WildCondor (Member # 434) on :
Not really, I felt pretty horrible for about a year on all the meds before I started seeing improvements.
Posted by springshowers (Member # 19863) on :
What is the normal pulsing method for Flagyl??
Posted by WildCondor (Member # 434) on :
2 weeks on at full dose and 2 weeks off. It can also be used non-stop for 2-3 months and then pulsed. I used to do the pulse 4 days on 3 days off for 2 weeks in a row, then 2 full weeks off. Taking slivers of pills, and other inadequate dosing does not count as pulsing.
Posted by springshowers (Member # 19863) on :
Ok... that is what I was wondering.. .. if 4 days on and 3 days off is normal?
If someone has done a couple months straight.. Then would 4 days on and 3 days off for two weeks and then take off two weeks make sense?
And I am talking about IV flagyl.. and 1500mg per day..
Also for Artemisinin what is the pulsing like. Does it mimic the Flagyl pulsing schedule?
And what is the dosing per day.. 200 to 600 per day? Or??
Posted by Parisa (Member # 10526) on :
My husband did five days on, two days off for three months total.
Posted by WildCondor (Member # 434) on :
Ok, when I started Flagyl it was 500 mg 4x per day every day for 3 months. After that, it was 750 Mg (Flagyl ER) 4x per day (total 3,000mg/day) for 4 days on then 3 days off for 2 weeks, then a full 2 weeks off. All the while being on other antibiotics such as Biaxin and Bicillin.
Flagyl is also used 2 weeks on full dose (2,000 mg/day) and 2 weeks off with other meds being taken every day.
There are other combinations of antibiotics that work too, that is just what I was on. Doses vary as well, some do 500 mg 3x per day along with other meds.
With artemesia it is 2 weeks on full dose, and 2 weeks off. Artemesia is usually combined with Mepron 2-4 tsp/ day along with Biaxin (1,500 -2,000 mg/day) or Zithromax (500-1,00 mg/day)
Some patients are able to determine clear cut 4 week cycles of flare ups, and some doctors can use that as the time frame for using pulse therapy.
Posted by txgirl09 (Member # 21612) on :
Thanks, Wildcondor. You are so helpful!
I'll have to talk to my dr about increasing my dose. Did you have much neuropathy with flagyl? Even on my lower dose, I'm having a some new/worse neuropathy which worries me.
Posted by WildCondor (Member # 434) on :
That can be a side effect of Flagyl. make sure your doctor knows you are experiencing this. You may need a lower dose, or to stop it altogether. Tinidazole may be easier to take.
Posted by springshowers (Member # 19863) on :
I have been reading up about Dr. J protocol methode
He believes that dosing every 24 hours does no make sense and does it M W F instead.
And besides the M W F thing he does 2 weeks on and then the next week off.
In that M W F also he pulses things like Flagyl on Th F so something like that..
Then also Art and Mepron.. Like you were saying Wild.
So kinda just a different spin on the Pulse and Cycling method..
Also gives Ringers on the Days off.
I am very close to this sort of protocol and finding I am making some good progress....
I am having to change Flagyl to Tindazole...
One top of above.. and 2 weeks on and 1 week off.. Then Every 6 weeks there are changes in the primary meds given and they are IV. Like a combo of two and then and addition of an oral of something.
Its a lot to think about and plan out.. but.. I think there is definately something to a plan like this..
Posted by mojo (Member # 9309) on :
Wild Condor you are my Idol when it comes to taking high doses of ABX!
And a perfect example of how that can work very well.
Thanks for sharing your info with us.
Posted by randibear (Member # 11290) on :
hmm, my doc had me pulse flagl at 500 per day for two weeks and off two weeks.
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