LymeNet Flash: CDC reports of 2 emerging Virus' assoc. with Mice and Rats.

This is topic CDC reports of 2 emerging Virus' assoc. with Mice and Rats. in forum Medical Questions at LymeNet Flash.

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Posted by Pinelady (Member # 18524) on :

http://www.cdc.gov/eid/content/16/2/308.htm

We report 2 cases of Sin Nombre virus (SNV) infection in field workers, possibly contracted

through rodent bites. Screening for antibodies to SNV in rodents trapped in 2 seasons showed that

9.77% were seropositive. Quantitative real-time PCR showed that 2 of 79 deer mice had detectable titers of SNV RNA.

In this study of human infections by SNV in Boulder County, Colorado, we identified 2

patients who had trapped rodents for ecologic studies. On June 14, 2005, a 24-year-old man was

admitted to Boulder Community Hospital with fatigue, headache, fever, and thrombocytopenia

(70,000 platelets/μL) but without cardiorespiratory compromise. A strip immunoblot

assay identified immunoglobulin (Ig) M and IgG against SNV N and Gn proteins. On July 6, 2005, a

22-year-old IgM- and IgG-seropositive woman was admitted to Boulder Community Hospital with fever

and dyspnea; she subsequently experienced bilateral lung infiltrates and thrombocytopenia

(116,000 platelets/μL). She required oxygen supplementation but recovered almost completely

by July 11. She reported performing fieldwork in the same period as did patient 1 but with no

overlap among the sites (the distances between sampling sites where the 2 field workers most

probably contracted their infections ranged from 6.4 to 9.8 km). Both patients engaged in field

activities involving manipulating traps and rodents in areas where deer mice were seropositive for SNV

http://www.cdc.gov/eid/content/16/2/328.htm
Abstract
We describe a case of lymphocytic choriomeningitis virus (LCMV) meningitis in a New

York, NY, resident who had no apparent risk factors. Clues leading to the diagnosis included

aseptic meningitis during winter and the finding of hypoglycorrachia and lymphocytosis in the

cerebrospinal fluid. LCMV continues to be an underdiagnosed zoonotic disease.

Critical or even fatal outcomes from LCMV are usually associated with transplacental

infections, and, more recently, solid organ transplantation. Congenital LCMV can result in

hydrocephalus, chorioretinopathy, macrocephalopathy, or microcephalopathy and can

mimic the classic TORCH (toxoplasmosis/Toxoplasma gondii, other infections, rubella,

cytomegalovirus, herpes simplex virus) pathogens. In 1 study of 26 infants with congenital LCMV,

9/26 (35%) died and 10/16 (63%) survivors had severe neurologic sequelae
==================================================

I find it interesting that neither report testing

for borreliosis, Yet one was tested for Syphilis.

And why in the heck are they reporting SNV now 5 years later?

Posted by map1131 (Member # 2022) on :

Don't you think it makes more sense that the vectors are feeding on these rats and then biting humans?

Yes, this these people were in direct contact with the rats, so inhaling bacteria spores or even contamination through the skin would make sense.

My health started falling after purchasing a lake home that was infected with mice droppings. No one had cleaned along baseboards, under or moved furniture in years.

The dropping were thick. I had a Rainbow vacuum at the time, it traps all dirt in water used in the vacuum. Inhaled something? Vector bite that was unknown?

Pam

Posted by LightAtTheEnd (Member # 24065) on :

Well, we're not biting the rats, I don't think. [Smile]

Posted by map1131 (Member # 2022) on :

I dunno some days I'm mad enough to fight/bite a rat.

Pam

Posted by sutherngrl (Member # 16270) on :

I think the CDC intentionally does not mention LD. Trying to take the attention away from it by bringing up other illnesses.

Posted by aliyalex (Member # 6976) on :

i live in a valley where there are many elk and deer and the mice are horrible. all houses and cars are infested. they eat the electrical systems in cars.

the other night in the middle of winter!!! i saw a deer tick next to my bed and squished it. then a mouse trap went off. hmmmmm.

hitchhiker?

[ 01-28-2010, 01:29 PM: Message edited by: aliyalex ]

Posted by Pinelady (Member # 18524) on :

Exactly. Transmission is possible.

But with Lyme may be hard to find like other

things. But like XMRV, it could help to have more information on signs and symptoms for those

chronically ill and not improved after antibiotics. Maybe they are looking for funds to

research. Saying XMRV is not the only bad boy we need to look at. I don't know. Need lots of dollars.

And all the researchers to come together for the

good of the people. Test the ticks and send them

on to be tested for the virus'.