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Posted by mysteryillness1970 (Member # 24588) on :
 
Daughters results are worrisome:

Alk Phosophates are HIGH

CD3 Immune Complex is VERY HIGH

Leukocyte Esterase shows a TRACE

Triglycerides are EXTREMELY HIGH (double the highest value)

Carbon Dioxide is LOW

Positive for anti-neuronal antibodies

My question is this normal for a child undergoing treatment and/or could this be caused by any particular supplement she might be taking?

IVIG treatment was mentioned and I have done some research but to be quite honest, it sounds a little scary!

ANY HELP would be greatly appreciated, I am very concerned. Thanks
 
Posted by seibertneurolyme (Member # 6416) on :
 
I am very curious as to what lab tested for the anti-neuronal antibodies? Very few docs including most LLMD's would not even think to test for this.

In my opinion your daughter's test results most likely indicate an infectious organism that is attacking her nervous system. Also it is obviously affecting either digestion or the gallbladder as well to cause the high triglycerides or she has possible issues with glucose metabolism.

Is the leukocyte esterase a blood test or from a urinalysis -- if from the urine indicates a possible bladder or kidney infection.

I personally would try IV antibiotics first before resorting to IV IgG -- which is extrememly expensive and would only be covered by insurance if her bloodwork shows deficiency in immune subclasses.

This is not medical advice. Just my opinion based on hubby's experiences.

Bea Seibert
 
Posted by mysteryillness1970 (Member # 24588) on :
 
Thanks Bea for responding right away, I am worried sick.

Leuk Est is blood

Glucose was on low end of high
 
Posted by mysteryillness1970 (Member # 24588) on :
 
She was taking a Magnesium and Potassium supplement for about six months, could that possibly have anything to do with all of this?
 
Posted by kitty9309 (Member # 19945) on :
 
Leukocyte Esterase is a urine test.

http://www.nlm.nih.gov/medlineplus/ency/article/003584.htm

"An abnormal result indicates a possible urinary tract infection."
 
Posted by mysteryillness1970 (Member # 24588) on :
 
Thanks Kitty!
 
Posted by Imhis4life (Member # 26581) on :
 
My son is 13 and has had High Alk Phos. for a long time. The Pediatrician and LLMD have assured me that this is normal in a growing teen and not uncommon in children.

There is a special test that can be done to determine if the alk. phos. is due to bone growth or other issue in the body.

Hope that helps a little..
 
Posted by mysteryillness1970 (Member # 24588) on :
 
Thanks so much, I will look into that!
 
Posted by kimmie (Member # 25547) on :
 
My daughter too has a high Alk Phos, her LLMD (Dr J) said this was actually normal in children due to bone growth and not to worry. WIth the liver you need to watch AST/ALT for kids.

My understanding is with the auto immune responses...anti neuronal antibodies, they are usually reversible with proper Bb treatment. IVIG could be beneficial, esp if insurance is willing to pay.

As far as risk, I was under the impression it is given under medical supervision (hospital setting) in the case of a severe reaction. Personally, I am not sure of the risk/benefit of IVIG treatment and would think you may want to discuss that with your LLMD. HOwever, if her symptoms are severe, it may be worth it.

Also, with severe neuro symptoms, which I have, IV ABX has made a huge differnece for me.

Best wishes.
 
Posted by mysteryillness1970 (Member # 24588) on :
 
Thanks again Kimmie!

Her doc mentioned IV, but I have heard horror stories about infection, expense..I am not opposed to it but it is so scary!

I am so glad to hear it has helped you! How long do you think you've had Lyme and how long were you on IV abx?
 
Posted by janet thomas (Member # 7122) on :
 
A very good alternative to IV is IM Bicillin with biaxin or ketek and flagyl or tindimax-for Lyme.

Expect a strong herx around 3-4 weeks, it's ok to take a short break then.

This is not medical advice but only my opinion.

Personally I would never get IV IgG-isn't it prepared from pooled human sera, a potential source of unknown infectious agents?
 


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