This is topic New Blood work results lyme negative RMSF Positive. What do these numbers mean?? in forum Medical Questions at LymeNet Flash.


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Posted by rsekrecre1 (Member # 35147) on :
 
Rocky mt Spotted fever, IgG 1:512

Rocky mt Spotted fever, IgM 1:64

Ebstein Barr virus Antibody to early >149.9

Ebstein Barr virus VCA IgG 483.0

Ebstein Barr virus IgM 13.1

Ebstein Barr virus AB NUC AG IGG 164.0

Bartonella henselae <1:64

Borrelia burgdorferi 0.59

Having all my same symptoms headaches, burning and nausea in stomach and tired and sore. Along with a list of other symptoms.
 
Posted by timaca (Member # 6911) on :
 
Actually it looks like you may have problems with both Rocky Mountain Spotted Fever and EBV.

You might be interested in this website for EBV: http://chronicfatigue.stanford.edu/infections/herpes.html

I'd try to see a doctor that could treat you for both.

Good luck,
Timaca
 
Posted by rsekrecre1 (Member # 35147) on :
 
I don't understand how the RMSF is so high, I tested positive in September and was on 100mg of doxy 2x a day.
 
Posted by timaca (Member # 6911) on :
 
It takes about 6 months for IgG antibody titers to decline. What were your titers in September? I don't know enough about RMSF IgM titers to comment....

You also may want to get tested for HHV-6 as well: http://chronicfatigue.stanford.edu/infections/herpes-tests.html People who are ill with EBV (which you may have) can also be ill with HHV-6.

Best, Timaca
 
Posted by seibertneurolyme (Member # 6416) on :
 
Sometimes RMSF takes multiple drugs to treat. The most common combo is doxy and rifampin.

If your symptoms have not improved in 4 months then I would be asking the doc about switching to a drug combo. Supposedly RMSF is easily treated, but that is not always the case.

Have you been tested for typhus or ehrlichia or anaplasma? -- would not be at all surprised if some of those did not also test positive. It could be a cross reaction if they test positive as all are related ricketssial diseases.

Are you running fevers or is your WBC low or any other routine bloodwork abnormal? Those could be clues that need more follow-up.

Bea Seibert
 
Posted by rsekrecre1 (Member # 35147) on :
 
my ehrlichia chaffeensis test was less than 1:64

WBC was 6.4

my MPV was 7.1 L

and my Lymphocytes were 44.0

everything else was in normal range.

In September my EBV results were as follows

Epstein Barr virus anti-diffuse 1:40H

Epstein Barr virus anti R/D 1:40H

Blood work numbers
--------1 Nov--------28 Dec
WBC-----5.5 ---------6.4
RBC-----4.97---------5.12
HGB-----15.8---------16.2
HCT-----43.7---------46.3
MCV------88.0--------90.5
MCH------31.9---------31.6
MCHC-----36.2---------34.9
RDW------13.4---------13.2
PLT CNT--213----------255
MPV------6.7 L--------7.1 L
NEUT%----30.3 L-------43.0
LYMPH%---56.2 H-------44.0 H
MONO%----11.6 H-------12.0
EOS%-----1.0----------0.8
BASO%----0.9----------0.2
NEUT#----1.7----------2.8
LYMPH#---3.1 H--------2.8
MONO#----0.6----------0.8
EOSIN#---0.1----------0.1
BASO#----0.1----------0.0

Here is some comparison blood work.
 
Posted by timaca (Member # 6911) on :
 
Looking at your Sept test results: I don't know what EBV "anti-diffuse" is. I'm guessing your EBV "anti R/D" is your early antigen. If that is the case, your new EA is much higher (although it is difficult to compare since you were tested at two different labs). But still, the first test isn't that high and your second test is as high as the lab measures! I'd stick with testing at the second lab for it seems to give you a much better picture of what is going on. It is important to find a lab that works for you and for the testing of that pathogen (my blood goes to 3 different labs for all the pathogens that I'm tested for) then stick with that lab so you can monitor the antibody levels (hopefully they drop with treatment). You did not put any results for RMSF in September.... It also could be that the EBV is a pretty recent primary or reactivated infection which is why the EA has risen so dramatically in the last few months....I would show both test results to your doctor.

I can't comment on your other labs (lymphs, etc) but I'd find a doctor to discuss and possibly treat your RMSF and EBV. I'd also consider getting tested for HHV-6 for if you have that too then that would be important to know.

Here is some info on HHV-6:

http://chronicfatigue.stanford.edu/infections/herpes-tests.html

http://www.hhv-6foundation.org/patients/hhv-6-testing-for-patients

Here is some info on EBV:
http://labtestsonline.org/understanding/analytes/ebv/tab/test

http://www.cdc.gov/ncidod/diseases/ebv.htm

Your EA for EBV is as high as the lab measures, plus you have a positive IgM. Those are worth noting and reading about.

Good luck,
Timaca
 
Posted by seibertneurolyme (Member # 6416) on :
 
I am no expert, but I think it is possible that the RMSF has cleared (based on the improvements in your routine bloodwork) and what you are left with is an active viral infection.

Your doc will have to be the one who decides whether to continue treatment for the RMSF or to just try treating the viral issues.

But the other point to consider is that you could also have a borrelia infection that requires ongoing treatment. What you are showing here is not a Western Blot test, but an Elisa I am assuming. For Lyme that test is notoriously unreliable.

I would get a Western Blot test if you have not done that.

Bea Seibert
 


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