This is topic Drank alcohol at family dinner... in forum Medical Questions at LymeNet Flash.


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Posted by NEMOM (Member # 31370) on :
 
I never drink anymore but a small glass of wine sounded good

after dinner on Sunday. I bet I literally had a 1/4 cup of wine.

Forgot that I can't drink with Rifampin. I have been nauseous

ever since. My stomach feels horrible. Water just sits on top

of the yucky feeling and makes me feel worse. I am soooo

thirsty. Any thoughts on how to get rid of the nauseous. I

haven't taken my meds since Sunday night because I do not

want to make it worse.
 
Posted by Keebler (Member # 12673) on :
 
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Liver support, minerals, nutrients with the very best healthful foods you can enjoy right now. My guess is that you may not be eating but your body really needs food now.

Eggs.

A potato, a yam, some squash . . . or even just a can of pumpkin is a good place to begin. Just warm it up, add a touch of vanilla and a bit of stevia or tiny, tiny bit of honey. Go light on the cinnamon or nutmeg right now, though as they can be a little intense.

Ginger Tea . . . Green Tea, too. Keep liquids up.

Ginger capsules would be best, more therapeutic in dose.

DGL - a special kind of licorice to let melt in your mouth or chew.

Good luck. Hope you feel better.
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Posted by Keebler (Member # 12673) on :
 
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FISH OIL for your brain cells.

Medical Mushrooms can be very nice, too. Adrenal support such as Cordyceps (a mushroom) is excellent for many reasons right now.

For your liver, Milk Thistle or Dandelion are the two most obvious helpers. Others:

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=3;t=030792;p=0

LIVER & KIDNEY SUPPORT & and several HERXHEIMER support links, too.
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Posted by lookup (Member # 44574) on :
 
Homeopathic Arsenicum album might help.

Rub DoTerra Deep Blue Rub onto your abdomen.

Cola syrup in water.

I even found putting magnet on my stomach has helped

(it's called grabbing whatever my hand could grab from my night

stand lol and amazingly it helped)
 
Posted by NEMOM (Member # 31370) on :
 
So far I have nothing on hand that has been recommended. [Frown]

Except the eggs which I have had for breakfast the last two days.

I'd love some Peppermint Tea but that would require a drive all the way across town.
 
Posted by Lymetoo (Member # 743) on :
 
Vitamin C??
 
Posted by wrotek (Member # 5354) on :
 
Alcohol causes blood sludge, it was described by Melvin H. Knisely . Folks with Lyme have already blood sludge
 
Posted by Razzle (Member # 30398) on :
 
Alcohol also depletes Vitamin B1, and shuts down Phase 2 liver detox. This is how chronic alcoholism causes cirrhosis.

Methylation and liver function is already impaired with Lyme, so why add more to this?

I wouldn't...
 
Posted by Keebler (Member # 12673) on :
 
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Add to all this, the rise and then drop in blood sugar. Lyme makes glucose management even harder so we have to be more careful.

By now, hope you are back to your normal. Still, as ideas come to mind, this is an important thread so others will have this detail.
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Posted by NEMOM (Member # 31370) on :
 
I felt better after about three days. I will definitely pass on the wine at the family Christmas dinner!
 
Posted by Lymetoo (Member # 743) on :
 
Found this info on alcohol intolerance .. Decided to add it here:

http://davidjernigan.blogspot.com/2015/09/are-you-sick-or-hungover-alcohol.html
 
Posted by ukcarry (Member # 18147) on :
 
Interesting piece from Dr J....thanks, Lymetoo.
 
Posted by Marnie (Member # 773) on :
 
Alcohol does a number on an enzyme called DAO = the copper dependent enzyme that helps break down histamine in FOODS. A LOT of foods are high in histamine.

During pregnancy, to protect a fetus from excessive levels of histamine, mom's DAO levels SOAR...I repeat...

SOAR.

Women also have less of the liver enzyme that breaks down alcohol (dehydrogenase) which is why men can tolerate drinking more alcohol than can women...generally speaking.

To prevent a hangover...Chinese researchers found SPRITE works - ONLY SPRITE BUT not "sugar free" Sprite. I don't know why/how the lemon-lime component might be key.

Rx: Zofran - sublingual - helps with nausea (serotonin - GI release of - is too high), but good old Cola syrup can help also (old remedy -Vermont country store catalog).
 
Posted by Lymetoo (Member # 743) on :
 
Dr J has a few suggestions in his article above.
 
Posted by Marnie (Member # 773) on :
 
Dr. J's comment about acetaldehyde - that's where Sprite comes into play:

http://phys.org/news/2013-10-chinese-team-sprite-hangover.html

ADH works = alcohol to acetaldehyde...ALDH (next enzyme) doesn't work - is supposed to break it down further into acetate.

I'd love to know (chemically) HOW...how *lemon-lime* -> more ALDH.

"What I found was that when the Alcohol Dehydrogenase and Aldehyde Dehydrogenase enzyme imbalances were corrected, as well as the Heme pathway in the body, which is responsible for making Cytochrome P450, another substance involved in completely metabolizing and detoxifying alcohol, that the symptoms and inability to drink normal amounts of alcohol, or their ability to use alcohol-based remedies, often improved dramatically."

http://davidjernigan.blogspot.com/

But Bb looks to upregulate the release of histamine...

"Notably, histamine interacts with CYP450 and it has been demonstrated
that

CYP2E1 and CYP3A were upregulated

in histidine de-carboxylase (HDC)-deficient mice."

(HDC is *increased* in *some* Mg deficient tissues.)

But...


***moderate alcohol consumption may cause intestinal CYP3A induction.***

Lymphocyte CYP2E1 and CYP3A4 mRNA levels did not correlate with CYP2E1 and CYP3A activities.


PMID: 15841467

So...both alcohol AND histamine can *upregulate CYP3A* - esp. if HDC is deficient.

CYP3A....These genes encode monooxygenases which catalyze many reactions involved in drug metabolism and

***synthesis of cholesterol, steroids and other lipids.***

Wikipedia.

High histamine "profile" (undermethylated) = high(er) cholesterol levels?


In conclusion, histamine suppresses hepatic LDL receptor expression via a non-H1 receptor-mediated pathway, and

***histamine reduces plasma HDL cholesterol via an H1 receptor-mediated pathway.***


PMID: 9112380

Claritin is a H1R antagonist...

???
 


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