This is topic New Green Tea Extract Study in forum Medical Questions at LymeNet Flash.


To visit this topic, use this URL:
https://flash.lymenet.org/ubb/ultimatebb.php/topic/1/133270

Posted by Rhiagel (Member # 21880) on :
 
A new study suggests that green tea extracts make abx more effective. Anyone have any experiences with this combo?

"In collaboration with professors at Montclair State, professor Chu has shown that when combined with antibiotics in vitro, thus modified green tea extracts can boost the effectiveness of some of the most commonly prescribed antibiotics such as Ampicillin by up to more than 400% when compared to antibiotics alone. Somewhat characteristic was the impact that a modified green tea extract had with Bacitracin, Chloramphenicol and Rifampin on S. marcescens, scoring a 292%, 119%, and 225% respective increase in inhibition (effectiveness)."

https://www.shu.edu/news/turning-tea-into-medical-breakthroughs.cfm

It seems to contradict this earlier study at least in mice fighting MRSA with amoxicillin:

"This study concluded that tea extract weakened the antibacterial effect of amoxicillin in MRSA infected mice. Tea drinking is not recommended in combination with amoxicillin treatment."

http://www.ncbi.nlm.nih.gov/pubmed/19653316
 
Posted by poppy (Member # 5355) on :
 
So how are patients/doctors supposed to figure these things out if we are faced with contradictory evidence? Or does this mean some abx work better and some don't? Gack.
 
Posted by mjo (Member # 7876) on :
 
Geez. the way of the world these days. One thing is good for you one day, bad the next.
 
Posted by Keebler (Member # 12673) on :
 
-
Just my thoughts: well, there is nothing that could ever stop me from enjoying several cups of organic green tea a day. For thousands of years, it has provided benefit.

Perhaps, were I to be taking Rx, I might not drink a cup with the Rx, but wait a little while. Telling people to not even drink tea, though, is like telling them not to eat colorful vegetables or bright deep colored berries that also have similar qualities of support to body organs.

I also think that green tea need not be messed with regarding making it an "extract".
-
 
Posted by Marnie (Member # 773) on :
 
Watch the specific antibiotic - green tea extract synergy.

Ampicillin, NOT amoxicillin to fight MRSA.

Epigallocatechin gallate synergy with ***ampicillin***/sulbactam against 28 clinical isolates of methicillin-resistant Staphylococcus aureus

epigallocatechin gallate (EGCg, a main constituent of tea catechins)

http://jac.oxfordjournals.org/content/48/3/361.long 2001

Synergy (EGCG?)with IP6 ;-)

http://webcache.googleusercontent.com/search?q=cache:jpnjtnFwPRUJ:http://scialert.net/fulltext/%3Fdoi%3Dijcr.2012.49.62


In green tea (albeit in much smaller amts) =

L-theanine, 200mg chewable tablets (100mg each) profoundly reduces anxiety within a few minutes.

L-Theanine is the "relaxing" component in green tea.

It is a non protein amino acid.

It increases brain alpha waves, (a good thing) while inhibiting anxiety at the same time.

http://www.ncbi.nlm.nih.gov/pubmed/18296328


What it impacts (!!!):

http://www.ncbi.nlm.nih.gov/pubmed/17182482

Serotonin has a blocking effect on sodium channels *in human airway epithelial cells*,
but the receptor subtype involved has not been established (Graham et al., 1992).

http://pharmrev.aspetjournals.org/content/50/4/515.full


Another compound in Green tea (EGCG) does this:

An enzyme called alpha-amylase helps break down starch into maltose and glucose in the body.

EGCG may inhibit these enzymes, according to the researchers.

http://tinyurl.com/jgp3hqr

EGCG...

Alpha-1 antitrypsin, which protects the body from a powerful enzyme called neutrophil elastase.

Neutrophil elastase is released from white blood cells to fight infection,

but

it can attack normal tissues (especially the lungs)

if not tightly controlled by alpha-1 antitrypsin.

***EGCG enhances the expression of alpha-1 antitrypsin***

by regulating the PI3/AKT pathway.

(EGCG = epigallocatechin-3-gallate)

Persons can have genetically low levels of this enzyme and genetic testing for (low levels of) alpha-1 antitrypsin is FREE (at least in my pulmonologist's office). It involved a simple skin pin pick and the blood sample was sent out to a lab.

I just did it - I'm reacting big time to red tide. Coricidin HBP for coughs and colds helps counter the toxins in red tide that impact the sodium channels (open). It is a H1 blocker too without the "sleepy" aspect.

The toxins released by red tide open the sodium channels and trigger histamine release.

(The toxins T17 and T34 are the ones impacting the sodium channels.)

This ***brevetoxin-induced bronchospasm*** was effectively blocked by

atropine,

the mast cell-stabilizing agent cromolyn,

***the histamine H1 antagonist chlorpheniramine, *** (Coricidin)

and the β2-agonist albuterol.” (inhalers and nebulizers)

I am taking this and it is helping:

In the drug Coricidin, chlorphenamine maleate is combined with the cough suppressant dextromethorphan. Coridicin HBP for coughs and colds.

Chlorphenamine is a H1 antihistamine. Also looks to

prevent the reuptake of serotonin and norepinephrine.

The anticholinergic (blocks acetylcholine) effect can be countered by taking Coricidin HBP for coughs and colds with a cup of coffee.

Albuterol depletes magnesium and potassium! Not good for me.

http://naturaldatabase.therapeuticresearch.com/ce/ceCourse.aspx?pc=08-40&cec=0&pm=5

Steroid shots (I was given) also deplete vitamin C, vitamin D (I'm on the low side) and K!

I wish I hadn't agreed to the steroid shots and dose pack when red tide is present.

P.S.

Look at what was given to a woman who got a scorpion bite (the toxin impacts sodium channels):

http://webcache.googleusercontent.com/search?q=cache:K9TYXTvSGH8J:http://www.scielo.br/scielo.php%3Fscript%3Dsci_arttext%26pid%3DS1678-91992010000400018

Uhm...malaria...

"Chlorpheniramine Analogues

Reverse Chloroquine Resistance

in Plasmodium falciparum by Inhibiting PfCRT"

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027738/

While chloroquine does not appear to be effective to destroy babesia microti...what about adding Chlorpheniramine to prevent their resistance

if B. microti is a co-infection?

[ 01-13-2016, 04:05 PM: Message edited by: Marnie ]
 


Powered by UBB.classic™ 6.7.3