LymeNet Flash: Can anyone help please?

This is topic Can anyone help please? in forum General Support at LymeNet Flash.

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Posted by ssaakk123 (Member # 7278) on :

Hi everyone,
I'm sooo glad this board exists. Thank you in advance.
I sent off my blood to IgeneX for Lyme tests (Western Blot). I'm trying to interpret my results, and I'm just not sure. I tested clearly positive for 4 out of the 5 bands needed if you have Lyme IGg. Plus, I tested IND (indeterminate) for 4 of these bands. For IgM Lyme test, I have 1 positive and 2 IND-- here you need 2 bands to have Lyme IgM.

So, question is: Does anyone know if the presence of weak, IND bands count as a band? If it does, then I have Lyme!! WOW!!!!!

Thanks for any help. I'm going nuts trying to figure this out!! IgenX won't talk to me about it and my dr won't be around to call them for a while...

Posted by HEATHERKISS (Member # 6789) on :

You definately have Lyme. Indeterminate means not positive or negative but they saw something.

To "me" (I'm not a doctor) that means positive. Just an opinion.

Heather

Posted by Lymetoo (Member # 743) on :

Welcome! Could you list the bands here that were positive and those that were IND?

Read this!

Western Blot explanation: http://flash.lymenet.org/ubb/Forum1/HTML/022767.html

It explains every band and much more!

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oops!
Lymetutu

Posted by Melanie Reber (Member # 3707) on :

Good evening Ssaakk123,

Welcome to LymeNet!

Listing the bands would be helpful, however, it is important to remember that sometimes, even the most ill among us will test negative. NO test is 100%.

This is where your doc comes into play...hope you have a good one.

Have you found the Canadian Lyme site yet? www.canlyme.com

My best,
Melanie

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C O L O R A D O * S U P P O R T * S Y S T E M
[email protected]

Posted by ssaakk123 (Member # 7278) on :

Thanks so much everyone.s
Here are my results:
Lyme IgG:
28 +
30 ++
31 IND
39 IND
41 ++
45 IND
58 IND
66 +
93 IND
Thre rest are -

Lyme IgM:
23-25 IND
28 +
30 IND
39 +
41 IND
45 +
58 IND
66 +
93 IND

What do you all think? Thanks for your welcome!

Posted by Lymetoo (Member # 743) on :

OK....

Bands 28 and 30 are outer surface proteins
41 is the flagella or tail. This is the most common borreliosis antibody.
66 is the second most common borreliosis antibody.
39 is the most specific antibody for borreliosis of all.
45 is heat shock protein

[so you have lyme]
Now, the "IND" or "equivocal" means they SAW something....so it's there....just not very pronounced. Read the WB explanation link. Dr C explains that in layman's terms.

That means that they SAW something on 93, which is the DNA or genetic material of borrelia burgdorferi, a classic hallmark borreliosis antibody.

And they SAW something on 23-25, and 31.....a classic hallmark borrelisosis antibody.

All of the IND's are important.

Welcome to our little club! UGH! At least you know what you have now.

Sorry it took me this long to get back to you.

------------------
oops!
Lymetutu

Posted by Lymetoo (Member # 743) on :

OOPS.....read the Western Blot Explanation link first.

Tincup's Links for new members
http://flash.lymenet.org/ubb/Forum1/HTML/009342.html

Dr. Joseph J. Burrascano's Guidelines http://www.ilads.org/burrascano_1102.htm

Rose's 15 Facts for Newcomers http://flash.lymenet.org/ubb/Forum1/HTML/011977.html

Camp A and Camp B http://flash.lymenet.org/ubb/Forum1/HTML/021395.html

Abbreviations for Lyme-speak
http://flash.lymenet.org/ubb/Forum1/HTML/020494.html

Making the most of your LLMD visit
http://flash.lymenet.org/ubb/Forum1/HTML/020605.html

Success Stories http://flash.lymenet.org/ubb/Forum1/HTML/022173.html

Western Blot explanation: http://flash.lymenet.org/ubb/Forum1/HTML/022767.html

The cause and spread of Lyme http://flash.lymenet.org/ubb/Forum1/HTML/032259.html

More info: http://www.ilads.org/

Lyme Wars http://www.wildernetwork.org/Lyme_Wars.html

Lyme Disease State Info http://www.lymeinfo.net/support.html

http://www.anapsid.org/lyme/matthewgoss/index.html

Posted by ssaakk123 (Member # 7278) on :

Thank you all sooo very much for the direction you have given me, advice, and support.

Boy, do I have my reading to do!!!
Be well!

Posted by Kara Tyson (Member # 939) on :

it is important to know that 5 bands are necessary to be included in CDC statistics, but not necessary to be diagnosed.

Posted by Lymetoo (Member # 743) on :

Because you have band 39 and show IND on the 93, I believe you have Lyme, as NOTHING else can cause these bands to show up. NOTHING.

I am not a dr.

Posted by Lymetoo (Member # 743) on :

REASONS WHY A SERONEGATIVE TEST RESULT MIGHT OCCUR

1. Recent infection before immune response
2. Antibodies are in immune complexes
3. Spirochete encapsulated by host tissue (i.e. lymphocytic cell walls)
4. Spirochetes are deep in host tissue
5. Only blebs in body fluid; no whole organisms needed for PCR
6. No spirochetes in body fluid on day of test
7. Genetic heterogeneity (300 strains in U.S.)
8. Antigenic variability
9. Surface antigens change with temperature
10.Utilization of host protease instead of microbial protease
11.Spirochete in dormancy phase
12.Recent antibiotic treatment
13.Recent anti-inflammatory treatment
14.Concomitant infection with babesia may cause immunosuppression
15.Other causes of immunosuppression
16.Lab with poor technical capability for Lyme disease
17.Lab tests not standardized for late stage disease
18.Lab tests labeled "for investigational use only"
19.CDC criteria is epidemiological, not a diagnostic criteria

Posted by bg (Member # 46416) on :

I noticed you had 4 positives on each.

2+ = 1; 3+ = 2; and 4+ = 3 said my LLMD

Make sure your dr. diagnosing you reports your positive lyme dx to your health dept. ok.

Yes, print off TREEPATROL & TINCUP'S COMBINED newbie links. Check off as you read as there are MONTHS of reading there. Tree constantly adds to his links so be sure to go back & print off NEW link list.

Also, please use specific topic for our limited time here ok....example, western blot results, need help! thank you.....there are 40-50 posts/replies daily here!

bettyg, Iowa