posted
Hi everyone, I'm sooo glad this board exists. Thank you in advance. I sent off my blood to IgeneX for Lyme tests (Western Blot). I'm trying to interpret my results, and I'm just not sure. I tested clearly positive for 4 out of the 5 bands needed if you have Lyme IGg. Plus, I tested IND (indeterminate) for 4 of these bands. For IgM Lyme test, I have 1 positive and 2 IND-- here you need 2 bands to have Lyme IgM.
So, question is: Does anyone know if the presence of weak, IND bands count as a band? If it does, then I have Lyme!! WOW!!!!!
Thanks for any help. I'm going nuts trying to figure this out!! IgenX won't talk to me about it and my dr won't be around to call them for a while...
Posts: 29 | From Toronto, Canada | Registered: May 2005
| IP: Logged |
HEATHERKISS
Frequent Contributor (1K+ posts)
Member # 6789
posted
You definately have Lyme. Indeterminate means not positive or negative but they saw something.
To "me" (I'm not a doctor) that means positive. Just an opinion.
Heather
Posts: 1974 | From ABERDEEN, NJ 07747 | Registered: Jan 2005
| IP: Logged |
Melanie Reber
Frequent Contributor (5K+ posts)
Member # 3707
posted
Good evening Ssaakk123,
Welcome to LymeNet!
Listing the bands would be helpful, however, it is important to remember that sometimes, even the most ill among us will test negative. NO test is 100%.
This is where your doc comes into play...hope you have a good one.
Bands 28 and 30 are outer surface proteins 41 is the flagella or tail. This is the most common borreliosis antibody. 66 is the second most common borreliosis antibody. 39 is the most specific antibody for borreliosis of all. 45 is heat shock protein
[so you have lyme] Now, the "IND" or "equivocal" means they SAW something....so it's there....just not very pronounced. Read the WB explanation link. Dr C explains that in layman's terms.
That means that they SAW something on 93, which is the DNA or genetic material of borrelia burgdorferi, a classic hallmark borreliosis antibody.
And they SAW something on 23-25, and 31.....a classic hallmark borrelisosis antibody.
All of the IND's are important.
Welcome to our little club! UGH! At least you know what you have now.
posted
Thank you all sooo very much for the direction you have given me, advice, and support.
Boy, do I have my reading to do!!! Be well!
Posts: 29 | From Toronto, Canada | Registered: May 2005
| IP: Logged |
Kara Tyson
Frequent Contributor (5K+ posts)
Member # 939
posted
it is important to know that 5 bands are necessary to be included in CDC statistics, but not necessary to be diagnosed.
Posts: 6022 | From Mobile, AL | Registered: Apr 2001
| IP: Logged |
posted
REASONS WHY A SERONEGATIVE TEST RESULT MIGHT OCCUR
1. Recent infection before immune response 2. Antibodies are in immune complexes 3. Spirochete encapsulated by host tissue (i.e. lymphocytic cell walls) 4. Spirochetes are deep in host tissue 5. Only blebs in body fluid; no whole organisms needed for PCR 6. No spirochetes in body fluid on day of test 7. Genetic heterogeneity (300 strains in U.S.) 8. Antigenic variability 9. Surface antigens change with temperature 10.Utilization of host protease instead of microbial protease 11.Spirochete in dormancy phase 12.Recent antibiotic treatment 13.Recent anti-inflammatory treatment 14.Concomitant infection with babesia may cause immunosuppression 15.Other causes of immunosuppression 16.Lab with poor technical capability for Lyme disease 17.Lab tests not standardized for late stage disease 18.Lab tests labeled "for investigational use only" 19.CDC criteria is epidemiological, not a diagnostic criteria
Make sure your dr. diagnosing you reports your positive lyme dx to your health dept. ok.
Yes, print off TREEPATROL & TINCUP'S COMBINED newbie links. Check off as you read as there are MONTHS of reading there. Tree constantly adds to his links so be sure to go back & print off NEW link list.
Also, please use specific topic for our limited time here ok....example, western blot results, need help! thank you.....there are 40-50 posts/replies daily here!
bettyg, Iowa
Posts: 1 | From US | Registered: Aug 2015
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
oops! 
Printer-friendly view of this topic