This is the part that interested me. (Hah, just cut to the chase, and tell me how to fix the problem.)
Treatment package for failing mitochondria
l. PACE - do not use up energy faster than your mitos can supply it.
2. FEED THE MITOCHONDRIA - supply the raw materials necessary for the mitochondria to heal themselves and work efficiently, namely D-ribose, Co-enzyme Q10, acetyl-L-carnitine, NAD and magnesium
3. ADDRESS THE UNDERLYING CAUSES 4. ADDRESS THE SECONDARY DAMAGE
Many of us have severe fatigue as part of our pattern of symptoms. Those of you who take the time to look at the article will notice that much of the information applies to people with Lyme.
Carol
Posts: 6947 | From Lancaster, PA | Registered: Feb 2004
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bejoy
Frequent Contributor (1K+ posts)
Member # 11129
posted
Tell me about NAD. Can you get enough of this through taking a B complex? Is there another way to get it besides taking Niacin that makes you flush?
-------------------- bejoy!
"Do not go where the path may lead; go instead where there is no path and leave a trail." -Ralph Waldo Emerson Posts: 1918 | From Alive and Well! | Registered: Feb 2007
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5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
Thanks for posting Marnie
What does NAD stand for?
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
NAD.
Nicotinamide adenine dinucleotide
Coenzyme
Comes from this:
A form of vitamin B3, (niacin) called nicotinamide.
Nicotinamide is joined with Ribose and ADP to form NAD+. So...
B3 + ribose + ADP -> NAD
In cells, most oxidations are accomplished by the
removal of hydrogen atoms.
Each molecule of NAD+ (or NADP+) can acquire two electrons; that is, be reduced by two electrons.
(Acquire electrons = reduced. How's that for confusing?!)
NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH.
However, only one proton accompanies the reduction.
The other proton produced as two hydrogen atoms are removed from the molecule being oxidized is liberated into the surrounding medium.
For NAD, the reaction is thus:
NAD+ + 2H -> NADH + H+
NAD participates in many redox reactions in cells, including those
� in glycolysis and most of those
� in the citric acid cycle of cellular respiration.
The reducing potential stored in NADH can be converted to ATP through the aerobic electron transport chain or used for anabolic metabolism.
ATP is the universal energy currency of cells, and the contribution of NADH to the synthesis of ATP under *aerobic conditions* is substantial.
However, under certain conditions (e.g. hypoxia) the aerobic regeneration of oxidized NAD+ is unable to meet the cell's immediate demand for ATP.
In contrast, glycolysis does not require oxygen, but it does require the anaerobic regeneration of NAD+.
The oxidation of NADH to NAD+ in the absence of oxygen is called fermentation.
Mindblowing...isn't it? How did anyone ever figure this all out?
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
Thanks Marnie for the detailed explanation
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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