Carol in PA
Frequent Contributor (5K+ posts)
Member # 5338
posted
Wow, great article.
Quote, edited: All of our antibiotics are designed to kill fast-growing microbes. Bacteria can weather these assaults by entering a dormant state, and waiting until the drugs have worn off.
But Kim Lewis from Northeastern University has now found...an antibiotic called ADEP4...it can completely clear severe and long-lasting infections in mice. It even kills...MRSA.
. This is just fabulous! But remember, most of the Lyme bacteria lives within our body's cells, and antibiotics can reach only bacteria in the blood.
Posts: 6947 | From Lancaster, PA | Registered: Feb 2004
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posted
If only....
Posts: 803 | From USA | Registered: Oct 2013
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TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
I wonder how massive the herx would be...they don't discuss that about the experiments with the mice.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
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Yeah, I was thinking the same thing, if it really does eradicate those critters so fast.
Posts: 922 | From Philadelphia | Registered: Sep 2012
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posted
Wow. Incredible validation for the kind of protocol that has knocked my son's arthritis into what is now a sustained (more than 18 months) remission. This is why we need very long term, high dose combination protocols, together with herbal treatments that break down biofilm.
This research is a very positive development. Now they have to test it on Lyme and see if it gets into the collagen and the brain.
-------------------- Son, 26, Dx Lyme 4/10, Babs 8/10 Had serious arthritis, all gone. Currently on Valtrex Daughter, 26,bullseye 7/11 arthritis in knees, cured and off all meds. . Self:Lyme, bart, sxs gone, no longer treating. Posts: 496 | From Washington, DC | Registered: Jul 2010
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WPinVA
Frequent Contributor (1K+ posts)
Member # 33581
posted
Wow. Such validation for the "resistance" of spirochetes to the standard courses of abx.
Posts: 1737 | From Virginia | Registered: Aug 2011
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sparkle7
Frequent Contributor (5K+ posts)
Member # 10397
posted
All of this stuff is very complicated... There are a few considerations in regards to this drug treating Lyme.
I'm not a scientist but B. burgdorferi is a very complicated pathogen. I think the article said that the drug is only useful on gram positive bacteria. B. burgdorferi is not gram positive as far as I know.
It's interesting info in any case.
Posts: 7772 | From Northeast, again... | Registered: Oct 2006
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B burgdorferi is gram-positive anaerobic according to pretty good sources, and there is one that explains which antibiotics work for gram-positive anaerobic bacteria.
Posts: 254 | From North Carolina | Registered: Nov 2013
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'Kete-tracker
Frequent Contributor (1K+ posts)
Member # 17189
posted
"antibiotics can reach only bacteria in the blood" Not quite correct, Carol. Abx in the bloodstream can lyse bacteria in tissue adjacent to the blood stream, as well. How well & how fast depends on the antibiotic & targeted microbe's sensitivity... and condition.
(Remember, penicillun kills microbes many cm.s away from the abx "drop" in the petri dish. ;-)
Posts: 1233 | From Dover, NH | Registered: Sep 2008
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Carol in PA
Frequent Contributor (5K+ posts)
Member # 5338
posted
Thanks Kete-tracker, that's good to know.
I had not seen that in the various information I've read.
Posts: 6947 | From Lancaster, PA | Registered: Feb 2004
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Catgirl
Frequent Contributor (5K+ posts)
Member # 31149
posted
Fascinating article!
-------------------- --Keep an open mind about everything. Also, remember to visit ACTIVISM (we can change things together). Posts: 5418 | From earth | Registered: Mar 2011
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map1131
Frequent Contributor (5K+ posts)
Member # 2022
posted
What makes us chronic lyme & co so different from resistant staph, strep or e-coli infected people?
We are much LOUDER patients. We've lost our patience with the powers that be.
There's millions and millions of us around the world being ridiculed by the medical establishment.
Pam
-------------------- "Never, never, never, never, never give up" Winston Churchill Posts: 6478 | From Louisville, Ky | Registered: Jan 2002
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GretaM
Frequent Contributor (1K+ posts)
Member # 40917
posted
I agree. Lyme patients are not the, "Yes doctor. No doctor. Whatever you say doctor," types.
Lyme patients have been through the wringer with the typical medical establishment. Most of us come out fighting.
The traditional docs hate us but the drug companies love us!
If we stay sick, we are a never ending source of income for Big Pharma.
It is money-motivation that keeps those docs telling us to treat symptoms, instead of cause.
I would LOVE LOVE LOVE for an antibiotic to come to market that eradicates spirochetes.
But realistically, it would me a huge loss of profits and revenue in North America.
And I don't think the powers that be will allow it.
Posts: 4358 | From British Columbia, Canada | Registered: Jun 2013
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I was wrong. I went by some "good authority" listing about Bb which said Lyme was gram-positive.
Now I know it is mildly gram-negative, NOT gram-positive.
I chose an antibiotic based on that wrong info!
Posts: 254 | From North Carolina | Registered: Nov 2013
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randibear
Honored Contributor (10K+ posts)
Member # 11290
posted
Hmmmm...if the disease doesn't kill you, the cure might.
-------------------- do not look back when the only course is forward Posts: 12262 | From texas | Registered: Mar 2007
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gigimac
Frequent Contributor (1K+ posts)
Member # 33353
posted
Yeah, randibear. I think if something killed all the lyme bacteria in me all at once it might just kill me too!! the herx could literally kill me.
Posts: 1534 | From Greensboro NC | Registered: Aug 2011
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ukcarry
Frequent Contributor (1K+ posts)
Member # 18147
posted
Fascinating article, thanks.
I am not alone in reacting badly to Rifampicin, so would hope that it isn't the only current antimicrobial they will pair this find with.
Posts: 1647 | From UK | Registered: Nov 2008
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