Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
β-methylamino-L-alanine (BMAA), an *amino acid*
produced by
cyanobacteria (blue-green algae), has been linked to
neurodegenerative disease in indigenous communities in Australia and the South Pacific (Guam) and more recently to sporadic Amyotrophic Lateral Sclerosis (sALS) and
Alzheimer’s disease (AD) in Canada and the USA.
Cyanobacteria are ubiquitously distributed in terrestrial, fresh water and marine environments and
due, in some cases, to mismanagement of these resources
human exposure to BMAA is increasing.
Of great concern is recent data showing BMAA is
***bioconcentrated by aquatic species***
raising the possibility that we could be subject to ‘silent’ exposure to BMAA
in the absence of any readily identifiable cyanobacterial blooms.
“It has been suggested that ***bb0666 ***encodes a putative N-acetylmuramyl-L-***alanine*** amidase involved in peptidogylcan synthesis critical for cell division.”
Why does that number not surprise me? Does the berberine metabolite mess with Bb's 16s (r)RNA?
Ribosomal *(r)* RNA genes are likely to be critical for survival and persistence in its hosts.
It appears berberine is metabolized to berberrubine which interacts with HP14, a
substrate of RNA
involved in RNA folding. (Linked previously).
P.S. Viruses such as HIV have RNA genomes that can be converted into DNA by an enzyme by an enzyme called reverse transcriptase.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
| IP: Logged |
Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
So this means that the RNA that can be converted into DNA may ultimately become incorporated into a cell as part if it's DNA? Is this how Viruses "hijack" cells to reproduce?
-------------------- -Razzle Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs. Posts: 4166 | From WA | Registered: Feb 2011
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/