This is topic Has anyone else tried Invanz? in forum Medical Questions at LymeNet Flash.


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Posted by KimDC (Member # 20699) on :
 
After 5 weeks of IV therapy, I've become allergic to Rocephin. My LLMD has ordered Invanz, 1 G per day, for 2-4 weeks. He's also prescribed oral Tindamax.

Has anyone tried Invanz and what was your outcome? Is 2-4 weeks sufficient?
 
Posted by Parisa (Member # 10526) on :
 
My husband did Invanz and we didn't notice any changes but it was toward the end of his IV treatment and he had already made alot of progress. I believe he did a couple months of it.
 
Posted by KimDC (Member # 20699) on :
 
Anyone else?
 
Posted by coltman (Member # 21272) on :
 
there is interesting post on lymemd about that drug. I would definitely try it if I had option available :

http://lymemd.blogspot.com/2008/11/ivanz-who-knew.html
 
Posted by coltman (Member # 21272) on :
 
Did some research about drug .Seems good stuff -csf penetration ,gram negative activity, resistance to beta lactamase. Downsides - vulnerable to efflux pumps (but so are other drugs) and HUUUGE price tag, - $800/ 1g? $30k /month? - more expensive than tigecycline lucky those whose insurance covers it
 
Posted by KimDC (Member # 20699) on :
 
coltman - thanks so much for the link and info.! I love the lymemd's blog! I'm feeling more optimistic about invanz, now. I guess I'm lucky that my insurance has covered it 100%.
 
Posted by Parisa (Member # 10526) on :
 
Coltman are you sure about the $30,000 price tag? Insurance didn't even blink although we did have a very good infusion company that got things authorized for us. Still, $30,000?
 
Posted by coltman (Member # 21272) on :
 
quote:
Originally posted by Parisa:
Insurance didn't even blink although we did have a very good infusion company that got things authorized for us. Still, $30,000?

I am not sure but only price I could find lists it at $800 per 1g.

You can easily check how much they charged the insurance company though (just ask them)
 
Posted by gridmonster (Member # 19280) on :
 
I am starting my 3rd week of once daily, I.V. Invanz. It is much easier on my system than I.V. Rocephin, and I am seeing slight, gradual, improvements on this medicine. I'm also taking oral Alinea, and Benecid.
The only side effect for me is a slight metallic taste in the mouth after my dose. That effect lasts about 2 hours. (Rochephin beat me up pretty badly.) Invanz is MUCH easier on my system.
I'm using a saline drip bag with a dry powdered Invanz bottle attached. You break an internal valve feeder seal to the powered medicine, squish and shake the saline bag mix them together, then start the drip.
 
Posted by KimDC (Member # 20699) on :
 
gridmonster - I'm happy to hear that Invanz is easier for you to tolerate and that you're seeing improvement. That's great!

I'm having a very hard time with it. It gives me severe muscle pain (mostly in legs), vertigo, and a feeling of being very sick. I've taken 2 days off because the pain became unbearable. I don't think I'll be doing more than 2 weeks of this stuff.

For others, the cost through my pharmacy is $70 per 1 gram.
 


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