posted
Does everyone with lyme have mitochondria damage? How do you know if you do?
Posts: 144 | From Pennsylvania | Registered: Jan 2011
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posted
DNA swab/ blood tests that cost 3 grand will tell ya. MitoDX or GeneDX
Posts: 871 | From orange county, ca. | Registered: Jan 2006
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posted
Sounds way too much. Don't all lyme patients have mitochondria issues?
Posts: 144 | From Pennsylvania | Registered: Jan 2011
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seekhelp
Frequent Contributor (5K+ posts)
Member # 15067
posted
Doubt it, but some here believe so. It's all speculation.
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008
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posted
Lyme is a trigger for Mito disease. If you already have the genetic genes for it , it can trigger gene expression. These tests can tell people 100% where the defect is in the Mito cascade.
I asked the geneticist what they do for it once found and they put you on high CoQ10 around 400mg - 600mg and carnitine in a prescription product called Carnitor. Other natural products are used also.
Of course LLMDs and alternative physicians have been doing this all along. The geneticist said yes but now through the testing they have the proof about the Mito cascade.
Posts: 871 | From orange county, ca. | Registered: Jan 2006
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posted
There are some standard blood and urine tests that can sort of test for mitochondrial issues.
I think lactic acid is tested, as it's usually higher than normal in those with a mitochondrial disease.
Genetics testing, as already mentioned, is another option.. But very very doubtful any insurance would pay for it (basically no chance).
Posts: 584 | From NY | Registered: Feb 2009
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seekhelp
Frequent Contributor (5K+ posts)
Member # 15067
posted
It's more complicated than all that. I went through the gold standard work-up including a deep muscle biopsy. No blood test can definitely tell mito issues regardless of what is said. it can only detect 'known; variants and those are few relative to the universe.
No test in isolation = mito unless some genetic tests as mentioned. Elevated lactic acid is an indicator. Elevated CPK may be too. There is also various amino acid tests (blood and urine), as well as a skin biopsy. I saw the best doc in the world in this field probably.
I'm betting I have Lyme, but mito was not diagnosed and I have ALL the muscle weakness / exercise intolerance issues so that's why I saw this presumption may be BS.
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008
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quote:Originally posted by seekhelp: It's more complicated than all that. I went through the gold standard work-up including a deep muscle biopsy. No blood test can definitely tell mito issues regardless of what is said. it can only detect 'known; variants and those are few relative to the universe.
Yep, but if the OP wants to test for markers, no harm doing the lactic acid/amino acid thing, just to check for abnormalities. It's certainly a lot cheaper than genetic testing.
But it'd only mean something (maybe) if it comes back abnormal. But if it does, perhaps highish doses of CoQ10 could be tested.
As for muscle biopsies, how accurate are they? I thought I read they are only so-so... as they can't take a biopsy from your heart, for instance -- well, they could -- but it's not really a place you'd want them to take a sample from. Just wondering if a muscle biopsy came back negative, does it necessarily rule out a mitochondrial disease, or does it simply mean they picked the wrong muscle sample?
Posts: 584 | From NY | Registered: Feb 2009
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posted
The tests I mentioned above are being used by Children's hospital of Los Angeles ( MitoDX). And this is the newest of the DNA ones. It by passes any muscle biopsy. Their site is very interesting. I am still wondering if I want to do it or not as it is so expensive.
Posts: 871 | From orange county, ca. | Registered: Jan 2006
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