Topic: CD57 vs. coinfection diagnosis. What's yours?
17hens
Frequent Contributor (1K+ posts)
Member # 23747
posted
If you would list your CD57 and infection/coinfection diagnosis, I sure would appreciate it. Maybe we can find a more detailed pattern beyond lyme=lowCD57 & coinfections=highCD57?
My CD57 started at 378, with treatment went down to 350. Lyme, Bartonella, Babesia - clinical diagnosis.
Hubby's CD57 started at 60, with treatment went up to 170. Lyme, Bart - clinical diagnosis.
Daughter's CD57 started at 57. Lyme, Bart - clinical diagnosis.
Good friend's CD57 started at 55. Lyme, Bart - clinical diagnosis.
-------------------- "My flesh and my heart may fail, but God is the strength of my heart and my portion forever." Psalms 73:26
bit 4/09, diagnosed 1/10 Posts: 3043 | From PA | Registered: Dec 2009
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posted
I don't know what I started at in the '90's when I first got sick.
But about 1-1/2 yrs ago CD-57 was about 30.
It's currently 140.
At the same time I was tested by Labcorp for Bb, and was still IGG +, and IGM+
In the past I have tested + for bart (h & q), babs (m & d), mycoplasma p, mycoplasma f, HHV1, EBV (through the roof).... there have been a couple more, but I can't remember now.
Even with the CD-57 having gone way up, I am as sick as ever. I think either it is predominantly co-'s at this point, or a cross reaction with my EBV.
(Or possibly that the CD-57 is worthless.)
This is a great idea for a thread. It will be interesting to see what, if any, patterns emerge.
Posts: 845 | From Eastern USA | Registered: Jul 2006
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seekhelp
Frequent Contributor (5K+ posts)
Member # 15067
posted
Cd 57 lowest was 28, highest 54. I tested positive for Lyme, Babesia WA-1, EBV (who doesn't so it's pointless), and Mycoplasma Pneumonia before.
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008
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Lymeorsomething
Frequent Contributor (1K+ posts)
Member # 16359
posted
Consistently between 30 and 40. Positive on 2 Igenex WB's. Positive on band 31 confirmation. Recently positive on a Lab Corp WB (IgM). Suspicious for Bart and/or BLO on Fry slide. Lightly IgG pos for Babs and I live in the northeast (shoreline) and I like cats
-------------------- "Whatever can go wrong will go wrong." Posts: 2062 | From CT | Registered: Jul 2008
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posted
Lyme pos (no joint pain, no muscle pain, no typical lyme symptoms, just serve brainfog and appetite loss/weight loss); Bartonella pos (very high titer, fell down somewhat while treatment); babesia neg (treated it anyway for 8 months to be "sure").
now.. since i treated babesia, my bartonella and borrelia meds are working not like 1 year ago, they work better?!
my CD57 is 240-390 since 2 years.
i don't think that borrelia is my main issue.. because like i said, i have no typical pain in my joints etc.. im focusing at bartonella/yeast/parasites at the moment.
greetz
Posts: 371 | From velocity of light | Registered: Sep 2009
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posted
CD57s of 10 and 11 (pathetically low) both times tested, last time a year ago. Tested Igenex positive for Lyme, babesia, ehrlichia, and mycoplasma.
Feeling 90% today, taking an antibiotic break, and CD57 is still likely low!
-------------------- Increasingly ill over past 10 yrs; treating since October '08. Posts: 180 | From Philadelphia, PA | Registered: Oct 2008
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fflutterby
Frequent Contributor (1K+ posts)
Member # 28081
posted
Treating since Sept 2010. End of Dec - CD-57 was 26 as of March it has gone up to 43. I am feeling better. Not 100% but 70%. Lyme does cause low CD-57s, but if you've got under treated co's it can be high.
-------------------- Psalm 46 1 God is our refuge and strength Posts: 1367 | From North Jersey | Registered: Sep 2010
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17hens
Frequent Contributor (1K+ posts)
Member # 23747
posted
So, fflutterby, you're saying that high numbers don't neccessarily mean you have co's, but rather undertreated co's?
Should I change the wording on the thread instructions to make this more useful? Anyone?
-------------------- "My flesh and my heart may fail, but God is the strength of my heart and my portion forever." Psalms 73:26
bit 4/09, diagnosed 1/10 Posts: 3043 | From PA | Registered: Dec 2009
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penguingirl
Frequent Contributor (1K+ posts)
Member # 28688
posted
Mine was 16 in Oct 2010 and in Feb 2011 went up to 28.
But my LLMD said that there can be a 30% swing in either direction so it's really just an estimate.
-------------------- Posts: 1204 | From USA | Registered: Oct 2010
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posted
20 1 1/2 years ago, now 50. Positive igenex for lyme and babesia.
Posts: 857 | From northern california | Registered: Dec 2009
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fflutterby
Frequent Contributor (1K+ posts)
Member # 28081
posted
No Hens, I believe that when you are still sick with a high CD-57 it is most likely the co-infections making you so sick or something else, besides LYME.
-------------------- Psalm 46 1 God is our refuge and strength Posts: 1367 | From North Jersey | Registered: Sep 2010
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MichaelTampa
Frequent Contributor (1K+ posts)
Member # 24868
posted
Started at 27, was around 60 for a lot of treatment duration, got up to 96 a couple months ago when treatment was slowing down, last 6 weeks now in the 68-70 range after more things added to my treatment.
For me it really has tracked fairly well what has been going on with symptoms and treatment.
Still treating.
Posts: 1927 | From se usa | Registered: Mar 2010
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17hens
Frequent Contributor (1K+ posts)
Member # 23747
posted
from my lyme friend "C" (not lymenet member)-
"I have a positive western blot for lyme and clinical diagnosis for bartonella.
We didn't do a CD57 test until 6 months after lyme treatment began and then it was 57.
Then I did another 7 mo. later and it was up to 63."
-------------------- "My flesh and my heart may fail, but God is the strength of my heart and my portion forever." Psalms 73:26
bit 4/09, diagnosed 1/10 Posts: 3043 | From PA | Registered: Dec 2009
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posted
We did not do the test before treatment. Now 399 I was Igenx cdc positive for Lyme and Ehrlichia. Clinical & energy testing for Babs, Bart, & Myco. Ehr is gone,Lyme down.No ABX all alternatives.
Posts: 905 | From Santa Cruz,Calif | Registered: Aug 2005
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nefferdun
Frequent Contributor (1K+ posts)
Member # 20157
posted
Mine was 57 in November. I tested positive at that time for Bb, babesia and ehrichlia.
I do not experience any Bb flares. I primarily feel babesia is causing my symptoms now. Last year I thought it was bart but the LLMD (who only goes by test results) says I do not have bart. So according to him it was Ehrlichia causing those symptoms.
It is funny that my CD-57 is below normal and I feel the lyme is under control but many of you with a high CD-57 are very sick.
Do you have monthly flares? If not, it must be co-infections.
Just found this and thought it is interesting:
" Patients with chronic LD and predominant neurologic symptoms had significantly lower mean CD57 levels than patients with predominant musculoskeletal symptoms (30+/-21 vs. 58+/-37 cells per microl, P=0.002). CD57 levels increased in chronic LD patients whose symptoms improved, while patients with refractory disease had persistently low CD57 counts."
That was from Dr S -
-------------------- old joke: idiopathic means the patient is pathological and the the doctor is an idiot Posts: 4676 | From western Montana | Registered: Apr 2009
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posted
CD57 was 19 5 years ago prior to any treatment. Clinical dx of Lyme, Bart, labs proving mycopasma, EBV, HHV-6.
5 years later, my CD57 is only up to 52. Sigh. But, I am feeling pretty good so I am not complainin'!
Posts: 206 | From In the shadow of a mountain | Registered: Feb 2011
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posted
CD57 is 323 after treating with azith.,plaq.,doxy.,amox.,tetra. for 1 year in '09. Pos.for lyme in '06 and, highly positive per Dr.C. Tampa in 01/11.
MichaelTampa
Frequent Contributor (1K+ posts)
Member # 24868
posted
quote:Originally posted by Sheryl777: I don't understand how to read my CD57 test. The results are: CD57+ 13 % lymphocyte CD57+ 5 % of WBC CD57+ 243 cells/uL CD57+/CD3+ 9 % lymphocyte CD57+/CD3+ 4 % of WBC CD57+/CD3+ 168 cells/uL CD57+/CD8+ 10 % lymphocyte CD57+/CD8+ 4 % of WBC CD57+/CD8+ 187 cells/uL CD57+/CD3+/CD8+ 9 % lymphocyte CD57+/CD3+/CD8+ 4(high) % of WBC CD57+/CD3+/CD8+ 168 cells/uL
Everyone seems to be mentioning a single figure. What should I be looking at?
The 243 is the score comparable to what is generally talked about. That's a pretty good score, showing, if reliable for you, that borrelia is not currently depressing the immune system substantially. It is not thought to say anything with regard to babesia or bartonella.
Posts: 1927 | From se usa | Registered: Mar 2010
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posted
Thank you Michael!
Posts: 258 | From Spokane, WA | Registered: Oct 2008
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CherylSue
Frequent Contributor (1K+ posts)
Member # 13077
posted
It was my impression that anything under 120 meant you would likely relapse with Lyme (Borrelia). If you had a score higher than 120 and still sick, it was a coinfection, not Lyme. Keep working on the those coinfections!
Posts: 1954 | From Illinois | Registered: Aug 2007
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posted
Mine was a 48 prior to treatment (Dec 2010) then after a month or so went up to a 60, then to an 80 and at yesterdays appt it was an 88 (5 months of treatment). HOping to get over 100 next time!
Posts: 376 | From New York | Registered: Jan 2011
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posted
mine was 155 in early FEbruary, when I was too sick to stand or walk! Tested positive Lyme Elisa three times between 2005 and 2010.
Makes sense, Bart or something else is definately my killer right now.
BTW, I did read somewhere that cd57 might be unreliable because one can have plenty of the killer cells measured by this test, but all of them could be weak and useless, so need to be able to test the quantity AND the quality of the K cells.
Again, all so confusing and so many unknowns...I am doubting everything lately!
Posts: 348 | From MA | Registered: Dec 2010
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MichaelTampa
Frequent Contributor (1K+ posts)
Member # 24868
posted
27 before treatment, diagnosed with borrelia and bartonella
up to 70 these days but still treating and now diagnosed with babesia as clinical diagnosis
Posts: 1927 | From se usa | Registered: Mar 2010
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