Topic: Mepron, Biaxin, Bactrim DS, and artemisinin...
RZR
Frequent Contributor (1K+ posts)
Member # 20953
posted
Is this a good combo?
Just want to make sure Biaxin can be taken with Bactrim DS and art...know it's good with Mepron. Drugs.com is not working for me right now...don't know what's going on.
-------------------- Tick bite May 2009 Diagnosed June 2009 Posts: 2329 | From SouthEast | Registered: Jun 2009
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MariaA
Frequent Contributor (1K+ posts)
Member # 9128
posted
I think that in theory there's a conflict between bactrim and biaxin due to potential heart side effects if you have QT syndrome (?), but there's a very similar protocol from Europe where they prescribed roxithromycin (a Biaxin relative) and Bactrim in high doses, and got good results in some Lyme patients. I have done the latter, not sure if anyone in the US really knows all that much about this combo and whether it's a good idea.
-------------------- Symptom Free!!! Thank you all!!!!
MariaA
Frequent Contributor (1K+ posts)
Member # 9128
posted
Doctors recommend artemesinin with any of those drugs and in some combos pretty frequently- I'm not sure drugs.com interactions checker will have any info on artemesinin, but it's given with those drugs very often.
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MariaA
Frequent Contributor (1K+ posts)
Member # 9128
posted
Here's what I got when I typed it in:
Limited data suggest that sulfamethoxazole-trimethoprim (SMX-TMP) may rarely prolong the QT interval of the electrocardiogram. Theoretically, coadministration with other agents that can prolong the QT interval may result in additive effects and increased risk of ventricular arrhythmias including torsade de pointes and sudden death. There have been isolated reports of QT prolongation and ventricular arrhythmias occurring in patients treated with SMX-TMP intravenously. However, a causal relationship has not been established, and the risk of clinically significant QT prolongation is unlikely at recommended dosages of SMX-TMP. In general, the risk of an individual agent or a combination of agents causing ventricular arrhythmia in association with QT prolongation is largely unpredictable but may be increased by certain underlying risk factors such as congenital long QT syndrome, cardiac disease, and electrolyte disturbances (e.g., hypokalemia, hypomagnesemia). In addition, the extent of drug-induced QT prolongation is dependent on the particular drug(s) involved and dosage(s) of the drug(s). Patients at increased risk for QT prolongation should be advised to seek medical attention if they experience symptoms that could indicate the occurrence of torsade de pointes such as dizziness, palpitations, or syncope.
-------------------- Symptom Free!!! Thank you all!!!!
posted
I had the Same, was safe for me, no QT problems
Posts: 371 | From velocity of light | Registered: Sep 2009
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janice victorov
Frequent Contributor (1K+ posts)
Member # 22937
posted
Jennie, currently on the same combo. Pm me and will tell you my dosage regarding biaxin. Janice
-------------------- jkv44 Posts: 1247 | From virginia | Registered: Oct 2009
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jackie51
Frequent Contributor (1K+ posts)
Member # 14233
posted
My doctor just added to my meds. I was and still am on Doxy. Added Biaxin, Mepron & Artemisin. Don't know about Bactrim.
PM me if you want dosage info.
Hope you're doing okay these days.
Posts: 1374 | From Crazy Town | Registered: Dec 2007
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jackie51
Frequent Contributor (1K+ posts)
Member # 14233
posted
I forgot to add: My doctor did an EKG prior to Biaxin. She won't put patients on Biaxin or Zith without a normal EKG.
Posts: 1374 | From Crazy Town | Registered: Dec 2007
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nefferdun
Frequent Contributor (1K+ posts)
Member # 20157
posted
I am doing mepron, bactrim, art and zithro. This protocol is used to by H. Don't know about biaxin. It is in the same family of drugs as zithro.
-------------------- old joke: idiopathic means the patient is pathological and the the doctor is an idiot Posts: 4676 | From western Montana | Registered: Apr 2009
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