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» LymeNet Flash » Questions and Discussion » Medical Questions » Went from CDC positive IGM to completely negative..what to make of it?

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Author Topic: Went from CDC positive IGM to completely negative..what to make of it?
gracefullyteaching
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hi Lyme friends,

over 2 months ago I tested CDC positive on a LabCorp Western Blot, IGM positive bands 23 and 41 (IGG negative). After 2 months of doxycycline and a few weeks of azithromycin added in, a retest showed nothing. (Was still on abx while tested). Am I correct that if it is truly Lyme, it would go from positive IGM to positive IGG? Feeling so frustrated and scared. Wondering if my neuro symptoms are something else. Any advice appreciated. I head back to the dr next week. Thanks!
gracefullyteaching
(symptoms for 9 months, no evidence of bite/rash, started with light headedness, panic attacks at night)

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gracefullyteaching

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Lymetoo
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No, it would not necessarily go from IgM to IgG. More chronic lyme patients have positive IgM's than IgG's.

There's really no need to test again once you are positive. If you're still sick you still treat.

PS .. LabCorp is not a very sensitive lab for Lyme testing.

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--Lymetutu--
Opinions, not medical advice!

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miapiaface
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Were you on abx before the first test? Just curious
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annier1071
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My husband had the same results and was cdc positive, took a month of doxy and was then completely negative on both but it was right after a tick bite that was known.

Tested through igenex

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Diagnosed with chronic neuro lyme 12/10 after 30 years of vertigo.2 tick bites in 3 yrs from upstate NY. Was on omincef for nine mths..zith and rifampin stopped.Remission~ All the pain and symptoms are back and I am not treating now with biaxin.

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gracefullyteaching
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miapiaface-- I was not on abx prior to first Westernblot which showed CDC positive. I questioned my dr (not a LLMD but an agressive treater of Lyme, had Burrascano's guildelines in her office), and she said I did not need to be off abx for retest. My next step is to get the Igenex done.

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gracefullyteaching

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Lymetoo
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quote:
Originally posted by gracefullyteaching:
My next step is to get the Igenex done.

-
And don't take antibiotics for at least two weeks prior to testing.

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--Lymetutu--
Opinions, not medical advice!

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annier1071
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Lyme,

I was abx the second time they did the western blot at Dr R? Two months into abx...He never mentioned stopping them? What will that do if you stop and retest?

Happy moms day

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Diagnosed with chronic neuro lyme 12/10 after 30 years of vertigo.2 tick bites in 3 yrs from upstate NY. Was on omincef for nine mths..zith and rifampin stopped.Remission~ All the pain and symptoms are back and I am not treating now with biaxin.

Posts: 788 | From New york..queens | Registered: Nov 2010  |  IP: Logged | Report this post to a Moderator
   

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