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» LymeNet Flash » Questions and Discussion » Medical Questions » l. glutemine supplement, bad for ALSlyme?

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Author Topic: l. glutemine supplement, bad for ALSlyme?
2young2dieMom
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Ny OD prescribed l.glutemine supplement to protect my stomach since its so irritated from all the abx and supplements I'm taking.

I just looked it up on the internet. Isn't this really bad for an ALS patient? Glutmate kills nerve cells!

Not so sure about Dr M in glastonbury, ct anymore...

--------------------
Dxd ALS 3/2010
Dxd cllinical Lyme 4/2010
Positive for Protomyxzoa but absolutely nothing else in Igenex

Posts: 417 | From central ct | Registered: Apr 2010  |  IP: Logged | Report this post to a Moderator
seibertneurolyme
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You are absolutely right -- everyone with severe neuro lyme needs to avoid glutamine and personally I think it is even more of a problem if you have G.I. issues.

DGL or even regular licorice supplements would be a better choice.

Bea Seibert

Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004  |  IP: Logged | Report this post to a Moderator
willbeatthis
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I know Gluatamine made me feel like I was coming out of my skin- I could not take it when advised as well.
Posts: 859 | From Southeast | Registered: Mar 2011  |  IP: Logged | Report this post to a Moderator
canefan17
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The reasons to avoid Glutamine in Lyme is it can provoke high levels of ammonia.

Research glutamine - ammonia connection


I made a big mistake and took high doses of glutamine once - had some major neuro symptoms (even sleep paralysis) the days following.

It all went away once I stopped the glutamine.


I recommend probiotics, aloe vera, prebiotics (rice bran, oat bran, FOS), yucca root, ACV

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FYRECRACKER
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i've found no issues with the glutamine. it helps with my sugar cravings as well. perhaps its one of those things some people can take and others cant tolerate

--------------------
www.mylymechronicle.wordpress.com

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MichaelTampa
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While I have heard it can increase symptoms, and having it cause a seizure would certainly be bad, I have really been helped by it in aiding repair of very damaged stomach/esophagus.
Posts: 1927 | From se usa | Registered: Mar 2010  |  IP: Logged | Report this post to a Moderator
Keebler
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-
Just stumbled upon this from last spring. For anyone searching, it's good to have detail below:
-----------

Caution: Aspartate; Glutamine; and Phenylalanine

Each of these can cause far too much nervous system and adrenal system stimulation for many who deal with lyme.
-------------

This information is especially for those with any degree of:

toxicity, exhaustion, anxiety, irritability, agitation, panic attacks, tremors, startles, or seizures:

it is best to avoid these three particular amino acids (other than in normal doses from food or maybe in a balanced formula with other amino acids & other nutrients, but not above the average daily dose.

Even at that, some people need to avoid excess foods that contain one or both of those as they can be too stimulating for the brain when it's already overstimulated from neuro-toxicity issues.

=========================================

http://www.itmonline.org/arts/glutamine.htm

AMINO ACID SUPPLEMENTS I: GLUTAMINE

with Reference to the Related Compound Glutamate
by Subhuti Dharmananda, Ph.D.

[Just beyond half-way down, see the section:]

Excerpts:

. . . GLUTAMATE IN NEUROLOGICAL DISEASES . . .

. . . In some neurological diseases, it is found that glutamate levels in the central nervous system become unusually high at sites of pathology.

This can occur, for example, if the rate of degradation of glutamate is slowed by an impairment of the enzymes that are involved.

Also, glutamate is excreted by immune cells that take part in inflammatory processes; the result is high local concentrations at the neurons in progressive neurological diseases such as MS and ALS. . . .

. . . The excess glutamate at the neuron acts as a poison; at high enough levels, the nerves exposed to glutamate can be completely and permanently damaged, so that they are no longer capable of transmitting signals.

Thus, while glutamate is a major component of the body, and an essential part of the nervous system, high levels localized in the nerve cells can be quite toxic . . . .

. . . Laboratory research has revealed that in the progressive, debilitating disease ALS, one of the many processes involved in disease progression appears to be damage of nerve cells by accumulation of glutamate.

In relation to multiple sclerosis, changes in control of glutamate homeostasis in the central nervous system might contribute to demyelination of the white matter of the brain (19).

[poster's interjection: lyme also causes demyelination, what that is:

http://en.wikipedia.org/wiki/Demyelinating_disease ] - article continues:

Based on preliminary animal studies, it has been suggested that glutamate dumped by immune cells can exacerbate the nerve damage (20). . . .

. . . The role of glutamate in neurological disorders has raised the question as to whether persons with such neurological diseases might have to be careful

not to get high levels of either glutamine or glutamate via their diet and/or by taking glutamine supplements. . . .

. . . � full article at link above.

==================================================

http://www.drlwilson.com/articles/epilepsy.htm

EPILEPSY AND SEIZURES - by Lawrence Wilson, MD

Excerpt:

[section] DIETARY ASPECTS OF EPILEPSY

Food reactions can trigger epileptic seizures. The main culprits are the following foods that are rich in glutamate and aspartate, two very excitatory amino acids:

------ See list at link above -------

. . . and the entire article as it may not seem like it by the title as not all lyme patients experience seizures.

However, the content relates very much so to the neuro-excitatory problems seen so very often in lyme disease & heavy metal toxicity.

--------------------

http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/113095?#000002

Terry Wahls, MD also discusses problem of excess glutamate / glutamic acid in those with MS or other diseases that are caused by or contribute to neuro-excitatory problems.
-

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