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I just spent a week in the hospital for picc line sepsis. Been off IV antibiotics since 2004. QUESTION- any of you who are getting IV antibiotics from a LLMD like Dr J. in Washington DC- what would your dosage of leviquin or generic form be? Did anyone ever get zoscyn? I ask because from a regular Infectious disease Dr I am getting some medication but I question the amount. Wanted to compare to typical Lyme amount.
The Levoquin is only 5ml a day. The Zoscyn seemed about the same. The Lyme amount seemed much more. Yes I am feeling better right now- been bedbound for 6 months. I was hoping they would give me enough to really help my Lyme too. I have been needing IV antibiotic for so long due to reactivation of my illness due to 3 more auto accidents, 3 more major surgerys, and an assault. Just want info for comparison purposes as Doctor isn't LLMD. It has been a long time since a LLMD had me on IV Antibiotics so do not know the dose of those meds. Thanks
Posts: 10 | From garner NC | Registered: May 2010
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joalo
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Up.
-------------------- Sick since January 1985. Misdiagnosed for 20 years. Tested CDC positive October 2005. Treating since April 2006. Posts: 3228 | From Somewhere west of the Mississippi | Registered: Aug 2007
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sammy
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Typical IV dosage of Levaquin is 500mg (this is in 100ml D5W) or 750mg (in 150ml D5W) once daily. This can be used to treat the coinfection Bartonella. It may also have some activity against Lyme.
Typical Zosyn dose is 2.25g, 3.375g, or 4.5g every 6hrs. I have not heard of this med being used for Lyme. It is is usually reserved for severe acute infections (like sepsis) that are resistant to other antibiotics. It may help with your Lyme symptoms though because it is a very potent broad spectrum antibiotic.
Take care Posts: 5237 | From here | Registered: Nov 2007
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TF
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From Burrascano Lyme Treatment Guidelines, pages 18-19:
"PARENTERAL THERAPY
Ceftriaxone- Risk of biliary sludging (therefore often Actigall is co-administered- one to three tablets daily). Adults and pregnancy: 2g q12 h, 4 days in a row each week .Children: 75 mg/kg/day up to 2g/day
Cefotaxime- Comparable efficacy to ceftriaxone; no biliary complications. Adults and pregnancy: 6g to 12g daily. Can be given q 8 h as divided doses, but a continuous infusion may be more efficacious. When exceeding 6 g daily, use pulsed-dose schedule Children: 90 to 180 mg/kg/day dosed q6h (preferred) or q8h, not to exceed 12 g daily.
*Doxycycline- Requires central line as is caustic. Surprisingly effective, probably because blood levels are higher when given parenterally and single large daily doses optimize kinetics of killing with this drug. Always measure blood levels. Adults: Start at 400 mg q24h and adjust based on levels. Cannot be used in pregnancy or in younger children.
Azithromycin- Requires central line as is caustic. Dose: 500 to 1000 mg daily in adolescents and adults.
Penicillin G- IV penicillin G is minimally effective and not recommended. Benzathine penicillin- Surprisingly effective IM alternative to oral therapy. May need to begin at lower doses as strong, prolonged (6 or more week) Herxheimer-like reactions have been observed. Adults: 1.2 million U- three to four doses weekly. Adolescents: 1.2 to 3.6 million U weekly. May be used in pregnancy.
Vancomycin- observed to be one of the best drugs in treating Lyme, but potential toxicity limits its use. It is a perfect candidate for pulse therapy to minimize these concerns. Use standard doses and confirm levels.
Primaxin and Unisyn- similar in efficacy to cefotaxime, but often work when cephalosporins have failed. Must be given q6 to q8 hours.
Cefuroxime- useful but not demonstrably better than ceftriaxone or cefotaxime.
*Ampicillin IV- more effective than penicillin G. Must be given q6 hours."
This is all for lyme treatment.
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