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» LymeNet Flash » Questions and Discussion » Medical Questions » High vitamin B6 level

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Author Topic: High vitamin B6 level
CSS
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Just got labs back from my LLMD (treating for Bart). Everything is in the normal range EXCEPT high level of vitamin B6.

One of my main symptoms is peripheral neuropathy in my feet and back. We have some other tests scheduled to look at why my B6 level may be high.

Right now I am discontinuing my Multi vitamins (high in B6) along with some other supplements that might be the cause or contributing.

Any suggestions on what to take that might be helpful?

Thanks
CSS

Posts: 22 | From California | Registered: Oct 2011  |  IP: Logged | Report this post to a Moderator
steve1906
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These are the Top 10 Foods Highest in Vitamin B6 - so if you are using them it may be something to concider:

http://www.healthaliciousness.com/articles/foods-high-in-vitamin-B6.php

Also> Here are some really good post on Vit-B6 - They talk about liver and kidneys.

http://www.alsforums.com/forum/people-als-pals/4285-high-levels-vitamin-b6.html

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Everything I say is just my opinion!

Posts: 3529 | From Massachusetts Boston Area | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
CSS
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Thanks Steve. I stopped eating red meat a few years ago, so what meat I do eat consists mainly of chicken and fish. LOTS of wild caught salmon. Also eat a ton of nuts. I will cut back on both to see if that helps. Looks like most everything has a fair amount of B6? Liver and kidney function both check normal.

LLMD thinks Bart may be main culprit as it does seem to get better and worse at times. The intensity level seems to vary from mild to strong. Trying to get a handle on what the heck is going on can be frustrating to say the least.

Thanks
CSS

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steve1906
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Hey CSS, check out this site below (posts) it really has a lot of info on B6...

http://www.medhelp.org/posts/Neurology/B6-pyridoxal-phosphate-levels-very-high-in-bloodwork/show/13007

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Everything I say is just my opinion!

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Razzle
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Too much B6 can cause peripheral neuropathy, from what I understand...but so can a deficiency. So my suspicion is that you may have difficulty converting from B6 to the activated form that is used by the body, hence the high blood levels.

B6 is water-soluble and shouldn't build up in the body - however, in the setting of difficulty converting the vitamin, the levels may be too high.

"Is supplementation with Pyridoxal 5 Phosphate necessary? Based on my initial review of the medical literature, it appears that P5P supplements may not be needed by most individuals since regular vitamin B6 supplementation raises levels of P5P.

However, there may be rare individuals who have a deficiency in enzymes that convert pyridoxine into pyridoxal 5 phosphate, and hence may benefit from P5P supplementation."
--from http://www.raysahelian.com/pyridoxal5phophatep5p.html

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-Razzle
Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs.

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CSS
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Thanks for the info on the web pages and the info on p5p. Doc has a spectra cell (?) ordered to see if the B6 is actually getting into the cells. Will see what that shows. I have stopped all vitamins for now.

I am hoping I just over supplemented. I hear it can take quite a long time for the nerves to heal.

Thanks
CSS

Posts: 22 | From California | Registered: Oct 2011  |  IP: Logged | Report this post to a Moderator
   

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