LymeNet Flash: Labcorp offers HLA DRB,DQB, ABC and DQA

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»	LymeNet Flash » Questions and Discussion » Medical Questions » Labcorp offers HLA DRB,DQB, ABC and DQA - ?

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Topic: Labcorp offers HLA DRB,DQB, ABC and DQA - ?

susank
Frequent Contributor (1K+ posts)
Member # 22150

posted

012542 - HLA DRB, DQB
016139 - HLA ABC
168002 - HLA DQA

I think most folks test only the 012542.

Does anyone know what the other two tests could reveal?
Sorry more stupid questions from me.

--------------------
Pos.Bb culture 2012
Labcorp - no bands ever
Igenex - Neg. 4 times
With overall bands:
IGM 18,28,41,66 IND: 23-25,34,39
IGG 41,58 IND: 39
Bart H IGG 40

Posts: 1613 | From Texas | Registered: Aug 2009 | IP: Logged |

Tincup
Honored Contributor (10K+ posts)
Member # 5829

posted

The main purpose for the test is to determine if you are a human or a mouse. Ok, so I don't know. But I am trying!

Here are some links that may be more confusing than not?

http://www.webmd.com/a-to-z-guides/tissue-type-test

http://www.aruplab.com/guides/ug/tests/2002788.jsp

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www.TreatTheBite.com
www.DrJonesKids.org
www.MarylandLyme.org
www.LymeDoc.org

Posts: 20353 | From The Moon | Registered: Jun 2004 | IP: Logged |

ChuckG
LymeNet Contributor
Member # 19093

posted

http://www.ncbi.nlm.nih.gov/pubmed/21945129

Virus Res. 2011 Sep 16. [Epub ahead of print]
HIV-mediated up-regulation of invariant chain (CD74) correlates with generalized immune activation in HIV(+) subjects.

Abstract
HIV Nef-mediated up-regulation of invariant chain (Ii chain, also CD74) is presumed to play an active role in HIV immunopathogenesis. However, this has not been definitely ascertained. In order to help elucidate this hypothesis, Ii chain, CD4, HLA-DR and HLA-ABC expression was analyzed ex vivo in monocyte-derived macrophages (MDMs) from HIV(+) subjects.

http://www.ncbi.nlm.nih.gov/pubmed/21118624

Frequency of HLA-DQA1 *0501 and DQB1*0201 alleles in patients with coeliac disease , their first-degree relatives and controls in Jordan.

Posts: 426 | From Berkeley, CA | Registered: Feb 2009 | IP: Logged |

susank
Frequent Contributor (1K+ posts)
Member # 22150

posted

Tks. B27 is a separate test from those I mentioned? Or would be seen in the A,B,C test?
I don't want to exclude anything important - but don't want to miss anything either.

For example - Sjogren's I think has a marker of DQA1 0501. That would fall under the third test/DQA - not the other two?

Also mentioned for Sjogren's is HLA-B8. What test would cover that?

Multiple Chem. Sensitivities I think has a marker of HLA B35. What test?

Thanks.

--------------------
Pos.Bb culture 2012
Labcorp - no bands ever
Igenex - Neg. 4 times
With overall bands:
IGM 18,28,41,66 IND: 23-25,34,39
IGG 41,58 IND: 39
Bart H IGG 40

Posts: 1613 | From Texas | Registered: Aug 2009 | IP: Logged |

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