LymeNet Flash: NIH-funded scientists sequence genomes of lyme disease bacteria

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»	LymeNet Flash » Questions and Discussion » Medical Questions » NIH-funded scientists sequence genomes of lyme disease bacteria

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Topic: NIH-funded scientists sequence genomes of lyme disease bacteria

Al
LymeNet Contributor
Member # 9420

posted

.
NIH-funded scientists sequence genomes of lyme disease bacteria

Published: Monday, October 18, 2010 - 12:33 in Biology & Nature
WHAT: Scientists supported by the National Institutes of Health (NIH) have determined the complete genetic blueprints for 13 different strains of Borrelia burgdorferi, the bacteria that cause Lyme disease. The achievement should lead to a better understanding of how genetic variations among strains may result in different courses of illness in people with Lyme disease, the most common tickborne disease in North America. The wealth of new genetic data will also help scientists develop improved ways to diagnose, treat and prevent Lyme disease. The first genome of a strain of B. burgdorferi was sequenced more than 10 years ago. The 13 newly sequenced strains include ones isolated from humans and ticks and represent a range of geographic origins. Together, the genomes provide a more complete picture of scope of natural variations in the microbe and the disease it causes.

The sequencing and analysis was led by Claire M. Fraser-Liggett, Ph.D., of the University of Maryland School of Medicine, and was performed at a Microbial Sequencing Center funded by the NIH's National Institute of Allergy and Infectious Diseases (NIAID). The research project was initiated by Steven E. Schutzer, M.D., of the University of Medicine and Dentistry of New Jersey-New Jersey Medical School, an NIAID grantee.

Additional support was provided by the National Institute of General Medical Sciences and the National Center for Research Resources, both components of NIH.

ARTICLE: SE Schutzer et al. Whole genome sequences of thirteen isolates of Borrelia burgdorferi. J. Bacteriology DOI: 10.1128/JB.01158-01 (2010).

WHO: Joseph J. Breen, Ph.D., Bacteriology Program Officer, Division of Microbiology and Infectious Diseases, NIAID, is available to comment.

Source: NIH/National Institute of Allergy and Infectious Diseases

Posts: 789 | From CT, | Registered: Jun 2006 | IP: Logged |

ChuckG
LymeNet Contributor
Member # 19093

posted

And here they are:
64b
72af
94a
118a
156a
297
29805
Bol26
CA-11.2A
JD1
N40
WI91-23
ZS7

Here is a complete list of sequenced Bb sensu stricto

Posts: 426 | From Berkeley, CA | Registered: Feb 2009 | IP: Logged |

Tincup
Honored Contributor (10K+ posts)
Member # 5829

posted

Yes, this 2010 study, and others like it, were funded not just by the NIH, but in part by the Lyme Disease Association.

It's right slimy the NIH couldn't see fit to share credit where credit is due, but then again, it is the NIH.

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www.TreatTheBite.com
www.DrJonesKids.org
www.MarylandLyme.org
www.LymeDoc.org

Posts: 20353 | From The Moon | Registered: Jun 2004 | IP: Logged |

sparkle7
Frequent Contributor (5K+ posts)
Member # 10397

posted

They did this back in 1997. Why are they doing it again?

http://www.nature.com/nature/journal/v390/n6660/full/390580a0.html

Posts: 7772 | From Northeast, again... | Registered: Oct 2006 | IP: Logged |

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