posted
I heard Rifampin is a great abx that targets it. I would love to hear additional ones as well.
-------------------- You name it, I've got it. Full-time medical anomaly. Posts: 432 | From Southeast | Registered: Aug 2011
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canefan17
Frequent Contributor (5K+ posts)
Member # 22149
posted
My only problem with Rifampin is it dramatically speeds up the metabolism of other abxs/meds. SO anything you take can have 50% or less efficancy.
Rifampin reduces Biaxin's effects by as much as 90% based on studies.
This is all done through the p450 metabolite(liver enzyme)
Posts: 5394 | From Houston, Tx | Registered: Aug 2009
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posted
I was just given Rifampin to start hitting the Bart, and I am worrying about the issue canefan brings up. I am also on Biaxin and Ceftin.
90% efficacy reduction for Biaxin? Wow.
Does anyone have a link to studies showing this much Biaxin is lost by adding Rifampin?
Posts: 331 | From West Coast | Registered: Jan 2012
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canefan17
Frequent Contributor (5K+ posts)
Member # 22149
I can't imagine doing Rifampin and Levaquin at the same time. I am having such a hard time with the Rifampin only.
I am a slow learner. I added the rifampin starting at the full dose, 600 mg, during a Tindamax pulse, and the herx took me down bad. I should have started the rifampin more slowly and not during a Tindi herx.
So I quit both the Tindi and rifampin for a couple of days to catch up with the detox.
I added back just rifampin today but only about 1/4 the dose, or 150 mg. In 20 minutes, I could feel the rifampin in my brain. It causes all sorts of neuro symptoms that rock off the charts.
So even with the 1/4 dose and skipping the Tindamax, I am having a reaction, same herx-like, out-of-control neuro issues.
Now I am not sure if the reaction to even the small dose of rifampin is a herx or If I am allergic.
Posts: 331 | From West Coast | Registered: Jan 2012
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