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» LymeNet Flash » Questions and Discussion » Medical Questions » A new Hypothyroidism study

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Author Topic: A new Hypothyroidism study
emla999/Lyme
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This new study kind of turns the current way of diagnosing hypothyroidism on it's ear. And therefore, this study's findings may have beneficial implications for people with chronic health conditions such as chronic fatigue and even chronic Lyme Disease.


http://www.ncbi.nlm.nih.gov/pubmed/23111240


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520819/


The authors of that new study concluded that a TSH blood level of greater than 2.0 uIU/L would indicate that you are hypothyroid and that you have hypothyroidism. And theres are some some doctors that believe a normal TSH level is between .3 - 1.5 and anything over 1.5 would indicate hypothyroidism.


http://tinyurl.com/bkv6dao


And in my opinion, this is imporant because most medical doctors will not diagnose a person with hypothyroidism unless their blood TSH level is around 4.5 uIU/L or higher. And thus, there are probably alot of chronically ill people that have hypothyroidism and they don't even know it. And more importantly, they are not being treated for it and they are suffering needlessly.


I also feel as though this study may be very important to people that have a chronic infection such as chronic Lyme Disease because having hypothyroidism can supppress your immune system and thus a person with hypothyroidism is more susceptible to contracting an infection and a person with hypothyroidism will also not be able to overcome an infectious illness as easily.


Also, people that have chronic fatigue may want to compare their blood TSH level to the blood TSH level that the authors said would indicate that you have hypothyroidism because a hallmark symptom of hypothyroidism is chronic fatigue.


A few quotes from that study:


"These preliminary results suggest that TSH levels > 2.0 uIU/L may be abnormal."


"This observation raises the possibility that negative health effects of mild, subclinical hypothyroidism with mild to modest elevations in TSH may begin at levels MUCH LOWER than those currently considered abnormal based on assigned normal reference range values with an upper reference level of 4.5 uIU/L."


.

[ 01-19-2013, 04:18 PM: Message edited by: emla999/Lyme ]

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Keebler
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-
Emla,

Thanks a bunch for all that great detail - and all the other good stuff you post, too.
-

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emla999/Lyme
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I thought that a list of symptoms that can be caused by hypothyroidism might be appropriate for this thread topic. So here goes.....


A list of symptoms that can be caused by hypothyroidism was taken from this website


http://www.stopthethyroidmadness.com/long-and-pathetic/


■Less stamina than others (chronic fatigue)
■Less energy than others
■Long recovery period after any activity
■Inability to hold children for very long
■Arms feeling like dead weights after activity
■Chronic Low Grade Depression
■Suicidal Thoughts
Often feeling cold
■Cold hands and feet
■High or rising cholesterol
■Heart disease
■Palpitations
■Fibrillations
■Plaque buildup
■Bizarre and Debilitating reaction to exercise
■Hard stools
■Constipation
■Candida
■No eyebrows or thinning outer eyebrows
■Dry Hair
■Hair Loss
■White hairs growing in
■No hair growth, breaks faster than it grows
■Dry cracking skin
■Nodding off easily
■Requires naps in the afternoon
■Sleep Apnea (which can also be associated with low cortisol)
Air Hunger (feeling like you can�t get enough air)
■Inability to concentrate or read long periods of time
■Forgetfulness
Foggy thinking (brain fog)
■Inability to lose weight
■Always gaining weight
■Weight loss (a small minority experience this)
■Inability to function in a relationship with anyone
■NO sex drive
■Failure to ovulate and/or constant bleeding (see Rainbow�s story)
■Moody periods
■PMS
■Inability to get pregnant; miscarriages
■Excruciating pain during period
■Nausea
■Swelling/edema/puffiness
■Aching bones/muscles
■Osteoporosis
■Bumps on legs
■Acne on face and in hair
■Breakout on chest and arms
■Hives
■Exhaustion in every dimension�physical, mental, spiritual, emotional
■Inability to work full-time
■Inability to stand on feet for long periods
■Complete lack of motivation
■Slowing to a snail�s pace when walking up slight grade
■Extremely crabby, irritable, intolerant of others
■Handwriting nearly illegible
■Internal itching of ears
■Broken/peeling fingernails
■Dry skin or snake skin
■Major anxiety/worry
■Ringing in ears
■Lactose Intolerance
■Inability to eat in the mornings
Joint pain
■Carpal tunnel symptoms
■No Appetite
■Fluid retention to the point of Congestive Heart Failure
■Swollen legs that prevented walking
■Blood Pressure problems
■Varicose Veins
■Dizziness from fluid on the inner ear
Low body temperature
■Tightness in throat; sore throat
■Swollen lymph glands
■Allergies (which can also be a result of low cortisol�common with hypothyroid patients)
Headaches and Migraines
Sore feet, sore heels (plantar fascitis); painful soles of feet
■ Having a cold butt, cold hindquarters
■colitis
irritable bowel syndrome
■painful bladder
■Extreme hunger, especially at nighttime
■Dysphagia, which is nerve damage and causes the inability to swallow fluid, food or your own saliva and leads to �aspiration pneumonia�.


.

[ 01-19-2013, 04:25 PM: Message edited by: emla999/Lyme ]

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poppy
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Let's hope the medical societies that handle thyroid issues takes this to heart. They are not well informed on the subject. Which is why a lot of people who need thyroid supplementation don't get it.

http://thyroid.about.com/od/gettestedanddiagnosed/a/2012-Hypothyroidism-Guidelines-Cause-Controversy.htm

Makes you wonder why these medical societies are considered to be the authorities when they keep getting it wrong.

Synthroid alone did not work for me, or for my mother, but she never get the chance to try anything else. And this has immune consequences too.

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nefferdun
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Very good information and list of symptoms. Did you mention a low body temperature taken first thing in the morning?

My entire life my normal body temperature was between 96.8 and 97 degrees F. Since starting LDN, it has been around 98.6.

--------------------
old joke: idiopathic means the patient is pathological and the the doctor is an idiot

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Robin123
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I bloodtested low thyroid, and since I've been on Armour thyroid, these symptoms have greatly reduced:

brain fog
dissociation
lack of sense of time passing

I also notice, reading through the list of symptoms above, that air hunger has greatly reduced. Interesting.

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Razzle
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I remember some other study showing the same - that TSH should be below 2 rather than 5 for the upper limit of the "normal range" on lab tests...but the medical community and most labs have ignored this.

See http://www.stopthethyroidmadness.com/ for more info about hypothyroid issues.

My TSH usually comes in at around 1.4...thankfully.

--------------------
-Razzle
Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs.

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emla999/Lyme
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Razzle,


There are even some doctors that believe that a normal TSH level is between .3 - 1.5 and anything over 1.5 would indicate hypothyroidism.


http://tinyurl.com/bkv6dao


Quote from that link:


"Any TSH value greater than 1.5 could be a strong indication that an underactive thyroid is present"


http://tinyurl.com/ak39m6d


Quote from that link:


"Health becomes SIGNIFICANTLY impaired above TSH levels of about 1.5. Any TSH above 1.5 should be addressed"


http://tinyurl.com/byptrxm



Quote from that link:


"Newer data suggests that the TSH level should be between 0.3 and 1.5"


There was even a study on hypothyroidism where they said that the desired TSH target was between 0.5 to 1.5.



http://www.healio.com/endocrinology/thyroid/news/online/%7B861D4E3D-744C-4149-AEA1-3E73459CBADD%7D/T3-therapy-may-be-substituted-for-T4-therapy


That information was presented at the endocrine society�s annual meeting!!


Endocrinologists are considered to be the world's experts on thyroid function but for some reason most medical doctors don't seem to be aware of those endocrinologists findings. So, there are probably alot of chronically ill people that have hypothyoidism but are not being treated properly for it.


And this is all unfortunate and sad becuase alot of people are probably needlessly suffering.


.

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Pinelady
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Endo's did not take into consideration that there is no more "normal" in the pop.s.

You can have perfectly looking normal hormone levels in the blood but if you have infected neurons that transverse those hormones to their desired locations CANNOT because those neurons are infected with stealth infections they will get the symptoms of low hormones and still suffer.

A new report from Japan on Testosterone.
TESTOSTERONE IS FUEL FOR THE FIRE

IF YOUR NOT KILLING BUGS.

Effect of Sex Steroids on Babesia microti Infection in Mice.

http://www.ncbi.nlm.nih.gov/pubmed/23249689

Which can help explain why 4 out of 5 cases of Autism is in Males.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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Pinelady
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Thanks for posting it emla999/Lyme.
I am stealing it...

What the Endo's have to do is get onboard to the truth of what denying people treatment

because of stupid tests and criminals who have denied Lyme exists

that has caused much suffering for NO reason...

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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birdie67
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Thank you emla [Smile]
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Tricky Tickey
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Interesting information here. I've been taking Levothyroxine for Hypo-T for a few years. I got off of it for 2 months, then my hair starts falling out. I wish I could treat it naturally, without the Levo-T, but would be afraid to venture out and try on my own.

Regardless, I still feel there is a natural treatment for this condition..I've heard Iodine, but haven't seen a ND to verify and get proper treatment. I tried on my own but not sure I hurt or helped the condition.

--------------------
Early Disseminated LD- 2010.
Currently doing acupuncture and yoga.
Negative Igenex (IND & Pos Bands)
ISSUES AFTER: Tendonitis, letter reversal, Low immune system.
PREVENTION:SaltC,Iodine,Humaworm,
Chiropractic.

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emla999/Lyme
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Tricky Tickey,

There are naturally derived thyroid meds available. Armour, Nature Throid and ERFA are just a few examples of naturally derived thyroid meds. But unfortunately most medical doctors don't prescribe them. They usually only prescribe the T4 containg Synthroid..... it's synthetic.


Natural thyroid meds


http://www.stopthethyroidmadness.com/armour-vs-other-brands/


.

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Pocono Lyme
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Thanks emla

I've been seeing a BHRT doc for a few months now and was diagnosed with hypothyroidism and glucocorticosteroid deficiency.

My TSH, Free T3 and Free T4 were within "normal" range.
Since going on Armour Thyroid and HC, my hair isn't falling out in clumps, MUCH less fatigue, starting to sleep better and many of those symptoms you listed I have/had with improvement.

Hoping this will be the key to me getting quality of life back.

Thanks for posting this as now dealing with yet another controversial illness, any validation one can get helps immensely.

--------------------
2 Corinthians 12:9-11


9 But he said to me, �My grace is sufficient for you, for my power is made perfect in weakness.� Therefore I will boast all the more gladly about my weaknesses, so that Christ�s power may rest on me.

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Jane2904
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Lots of good info. Thanks.

Anyone notice more fatigue when they started taking Armour Thyroid?

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emla999/Lyme
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Jane2904,

Some people can experience fatigue when they first start on Armour.


And have you had your Reverse T3 (RT3) blood levels checked?


I ask this because if your RT3 is high then taking Armour may actually make you feel worse. And you may need to take a thyroid med that contains only the T3 hormone.

Armour contains both T4 and T3 but if you have high RT3 you may not be able to tolerate a T4 containing med such as Armour.


You can read more about that on the link down bellow.


http://www.stopthethyroidmadness.com/reverse-t3/


.

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Pocono Lyme
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Jane 2904,

When I started Armour, definitely more fatigue.
That was with only 15mg. I was to increase by 15mg weekly but couldn't do it the second week.

I pushed through and increased it starting the third week. I crashed. That was proof that I needed hydrocortisone due to adrenals not working properly.

Since adding the HC, big difference. It is a trial and error type of thing to get on the proper dose and time of day to take the HC especially with increased activity/stress.

--------------------
2 Corinthians 12:9-11


9 But he said to me, �My grace is sufficient for you, for my power is made perfect in weakness.� Therefore I will boast all the more gladly about my weaknesses, so that Christ�s power may rest on me.

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Jane2904
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I will have to look at labs.

Thanks Emla and Pocono. [Smile]

Glad things are working out for you Pocono.

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Lymetoo
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quote:
Originally posted by Pinelady:
[QB]

A new report from Japan on Testosterone.
TESTOSTERONE IS FUEL FOR THE FIRE

IF YOUR NOT KILLING BUGS.


-
What do you mean?

--------------------
--Lymetutu--
Opinions, not medical advice!

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Pinelady
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Effect of Sex Steroids on Babesia microti Infection in Mice.

http://www.ncbi.nlm.nih.gov/pubmed/23249689

Abstract

Sex-based-differences are known to affect susceptibility to protozoan infections,

but their effects on parasitemia and clinical symptoms in Babesia infections remain unclear.

We examined the sex-based susceptibility

of various mouse strains to Babesia microti Munich strain infection.

In all strains, male mice exhibited significantly higher peak parasitemia and more severe anemia

than female mice.

Testosterone and estradiol-17β treatment caused

an increase in parasitemia and aggravation of anemia.

Orchidectomized male mice receiving testosterone exhibited smaller splenic macrophage populations three days after infection,

smaller B cell populations 10 days after infection,

and reduced splenic tumor necrosis factor-α and interferon-γ mRNA expression

than mice that did not receive testosterone.

Mice receiving estradiol-17β did not exhibit immunosuppressive effects.

Thus, a weakened and delayed innate immunity response

may lead to acquired immunity failure.

The results suggested that testosterone directly affects T or B cells,

leading to delayed acquired immunity,

dramatically increased parasitemia,

and severe anemia.
======================
Which can help explain why 4 out of 5 cases of Autism is in Males.

If your killing infections you shouldn't worry too much about it,

but using testosterone without killing bugs could make you much worse in more ways than one!

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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Pinelady
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I should also mention they had no idea how B cells or Macrophages even worked till now

and as long as they keep infecting us we never will....
-----------------------------

It appears that the upregulation of a single transcription factor can set in motion a series of events

that can transform a B cell into a macrophage.

It is unclear whether such processes might occur naturally.

However, Hodgkin's lymphoma cells express myeloid markers;

and although nearly devoid of B cell markers,

they do exhibit IgH VDJ rearrangements suggesting

that they might have a link to the B cell lineage.6,7

Consequently, it is plausible that processes similar to the described B cell to macrophage conversion

could take place under certain pathological conditions.3
http://www.rndsystems.com/cb_detail_objectname_FA04_CommittedBCellMacrophage.aspx

http://www.ncbi.nlm.nih.gov/pubmed/20468007
Macrophage polarization to a unique phenotype driven by B cells.

Here, we report for the first time the essential role of B cells in regulating macrophage (Mφ) phenotype.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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