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» LymeNet Flash » Questions and Discussion » Medical Questions » Indeterminate

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Author Topic: Indeterminate
JLM
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Can someone please explain to me what indeterminate means on the bands. I understand the + or ++ etc. It would seem to me that there is either something there or not.
Posts: 10 | From Massachusetts | Registered: May 2013  |  IP: Logged | Report this post to a Moderator
Lymetoo
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"If enough of the complexes are formed, eventually it may be seen with the naked eye as a dark band. - Band intensity reflects how dark or wide it is. Controversy exists about band intensity.

Many would say the " +/-" equivocal ["IND"] bands are not significant. The problem I have with that, is that there are "-" negative bands. The lab has no trouble calling some bands negative. So they must be seeing something when they put "+/-" at some bands.


The only thing that makes sense, is that there is a little bit of that antibody present in your serum. If the "+/-" equivocal is reported on the borrelia associated bands, it is usually significant, in my clinical experience. This is a strong clue that I am on the right track."

--Dr C of MO

from:

Western Blot Explanation
http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/42077

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--Lymetutu--
Opinions, not medical advice!

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faithful777
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My LLMD would call an indeterminate band a positive band. If something is seen and the lab can't call it negative, she would consider that they saw some reaction to the antibodies.

--------------------
Faithful

Just sharing my experience, I am not a doctor.

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randibear
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i had alot of the inter...and then mostly two ++...

the doctor said borderline...but to me with my symptoms, it was lyme...

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do not look back when the only course is forward

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Robin123
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I would agree, that there was something there to cause an indeterminate band, so to me, it's another indication of positive.
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Catgirl
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In ILADs speak, it would mean most likely positive. In the land of allopathic, it means negative. The correct diagnosis for lyme is a clinical one anyway, so these tests don't really matter. I never got hung up on them (positive or negative). I just treated.

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--Keep an open mind about everything. Also, remember to visit ACTIVISM (we can change things together).

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Crawgir1
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My LLMD said that IGenX got into trouble for calling too many positive bands, and so when the positive is low, they label it indeterminate.
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JLM
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Thank you everyone! It takes awhile to get the hang of what all of this means and it's significance or insignificance.
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Keebler
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-
In addition to others' good replies some links for your reference file.

While I agree that (along with symptoms) "indeterminate" is a positive marker as it is reading something that is there, see all the considerations with testing and issues that can keep a test from being the best it can be:


http://www.anapsid.org/lyme/lymeseroneg.html

Reasons for False Negative (Seronegative) Test Results in Lyme Disease


http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=2;t=015508;p=0

Diagnosing Lyme Disease (&/or whatever else is going on)

Other tick-borne infections and other chronic stealth infections - as well as certain conditions that can hold us back - are discussed here.


http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=2;t=013239;p=0

What is a LLMD? LL ND? What is ILADS?

WHY you need an ILADS "educated" or "minded" Lyme Literate doctor (whether MD or ND, or both) - starting with assessment / evaluation.
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randibear
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is it sort of like being a little pregnant???

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do not look back when the only course is forward

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Rumigirl
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At the U of New Haven Lyme Conference a few weeks ago, Dr. J S of Igenex said that with the indeterminate (+/-) bands, it meant that one person saw it as +, and one saw it as -.

I agree, it IS like being "a little bit pregnant!"

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