posted
I had a high B6 level last fall. I haven't taken multivitamins since then. Because it's been over 6 months, I figured I would try a half dose. I took this for 4 days, and every day I got terrible tingling in my legs and arms. When I connected the two, I stopped taking the multivitamin, and the tingling got better.
My question is, are there any conditions that would cause the body to not be able to process/excrete vitamin B6? I can't find anything. The only thing I have seen is that maybe kidney problems would cause this.
Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
Methylation defects may cause this.
The body uses active forms of B vitamins for methylation, but if the enzymes used to convert the B vits. to the active form are not functioning correctly, then the B vits. will build up to toxic levels in the body.
Also, some foods are very high in B vits., so you may not need a supplement.
And some gastrointestinal microorganisms ("friendlies") make B vitamins, and if you have a healthy dose of gut microbes, then you may not need to supplement.
-------------------- -Razzle Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs. Posts: 4166 | From WA | Registered: Feb 2011
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- Yes, as Razzle says, methylation issues should be considered.
Also the KIND of B-6 you have been taking may not have been the exact form YOUR body requires, it may have been unusable but could still then register high as it is stored instead of used.
Also as Razzle points out, you may be getting enough in your foods.
PCP (Pyridoxal-5-Phosphate) is the better way to get it for those who need B-6.
All forms of B-6, natural or synthetic, must be converted to P5P, another natural form, for the body to use it. . . .
. . . Dr. Larsson linked the effect to bloodstream levels of pyridoxal-phosphate (PLP), the main active coenzyme form of vitamin B6.
Pyridoxal-phosphate is also known as pyridoxal 5-phosphate or (as we referred to it above) P5P. . . . -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- Search: Amy Yasko, methylation
Search: Sarah Myhill, methylation
and then some of the LL doctors who have explored this topic regarding how it often affects those with lyme. -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
posted
Thanks, I was thinking methylation. I'll look more into it.
I was wondering if anything like kidney problems, adrenal or thyroid issues might cause this. Sounds cooky, but, a psychic told me a few years back that my problems were with a set of organs, she thought it was my kidneys, but, not sure. Of course, kidneys are always fine on tests, but, I have definite adrenal issues (which are also fine on blood tests, just lots of adrenal symptoms).
It's just so strange that a half dose of a regular multivitamin could give me such bad tingling in my legs.
Posts: 418 | From NJ | Registered: Sep 2007
| IP: Logged |
Judie
Frequent Contributor (1K+ posts)
Member # 38323
posted
I agree, methylation problems.
My doc had me take folapro (you can also take actifolate) for a couple days (one before bed) and then had me take B6 (one before breakfast).
She said you have to do the methylation vitamins in a certain order or the won't work right (you'll get sicker instead of better).
"a psychic told me a few years back that my problems were with a set of organs, she thought it was my kidneys, "
You might want to consult a doctor of Chinese medicine. They'll be able to tell you what organs need help.
Posts: 2839 | From California | Registered: Jul 2012
| IP: Logged |
posted
The one and only time I had B6 tested my result was twice the upper limits of normal. Hardly a shrug, not a word from any MD. This was at a time of probably my worst lyme symptoms, about a month or two before I was finally dx.
This study was done by a neurologist. I did read up on it and there is some neurologic relationship.
I won't take a multivitamin for this reason.
Posts: 478 | From Third Coast | Registered: Feb 2011
| IP: Logged |
beaches
Frequent Contributor (1K+ posts)
Member # 38251
posted
Be sure to check all the supps you're taking too.
There's one for adrenals...adrecor or adrenocor or something like that (sorry can't remember) that has very high B6 levels.
DD's B6 levels were off the charts and we had to d/c this supp. Have yet to retest but hoping levels are closer to normal.
Razzle, didn't know methylation issues can cause this. Thx for that info.
Posts: 1885 | From here | Registered: Jul 2012
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/