dbpei
Frequent Contributor (1K+ posts)
Member # 33574
posted
I remember my first LLMD telling me that she thought my vagus nerve was 'blocked' when she used some type of laser light on me. I moved on to someone else and never did quite figure out what this was, but since that time, have always felt that the bulk of my illness was around my neck and skull where I was 'blocked'.
Here is a good website with description and pictures...
posted
The vagus nerve is frequently damaged with Lyme and it can cause digestive problems.
The vagus nerve is involved in control of the stomach and problems with the vagus nerve can cause gastroparesis.
I had gastroparesis in 2011-- really painful and I lost 17 pounds in one month from not being able to eat. Lyme treatment (antibiotics) and parasite treatment (prescription anti-parasitics and liver flushes) both really helped.
It went away with Lyme treatment.
Definitely, vagus nerve symptoms can be Lyme.
-------------------- Son, 26, Dx Lyme 4/10, Babs 8/10 Had serious arthritis, all gone. Currently on Valtrex Daughter, 26,bullseye 7/11 arthritis in knees, cured and off all meds. . Self:Lyme, bart, sxs gone, no longer treating. Posts: 496 | From Washington, DC | Registered: Jul 2010
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I have heard lots linking the vagus nerve and gastroparesis. I feel lucky I thankfully do not have that.
My llmd (he is my new doctor the last several months) believes my vagus nerve is currently irritated from "chronic inflammatory response syndrome". It's all new to me to be honest.
We thought I might have lyme, so I began seeing a llmd. He didn't really think lyme wasy problem but tested regardless and it was negative. He ran several other tests including the Shoemaker panel for mold and biotoxins.
To my surprise, I have 2 genes that don't allow me to detox AND show markers of biotoxin illness. My doctor said the numbers are unmistakeable and definitely show chronic inflammation from these toxins.
Do you think the vagus nerve can be irritated and affected by this as well (even without lyme)?
Do problems with that nerve cause other issues other than digestive?
The Autonomic Nervous System (ANS) controls many organs and muscles that work in an
***involuntary, reflexive manner.***
The above is attributed to *brain delta waves* (slow waves)...controlling heart beat, kidney function, digestive functioning and respiration...all under "involuntary control".
In fibromyalgia, delta-wave sleep is interrupted into alpha-wave sleep, a much lighter sleep phase.
If you were to go thru a sleep study, it is likely they would find "alpha wave intrusion" = awake, eyes closed, relaxed, and the strongest EEG signal.
During delta wave sleep, neurons are inhibited by GABA (the brain "brake"). In other words...that is what is supposed to be happening.
Insufficient GABA = less delta sleep. The brain may thus be using glutamate (not converted to GABA) as an alternative fuel to glucose...in a jam.
"Glutamate also serves as an important potential fuel reserve. The oxidation of glutamate to oxaloacetate yields 12 ATP per molecule of glutamate. Therefore, when the brain has insufficient glucose concentrations or glycolytic flux is reduced, the brain mobilizes glutamate as a fuel (17). In this regard, the energy available from glutamate is similar to glucose as a fuel reserve."
It is thus critical to get inflammation down, to restore GAD to restore the conversion of glutamate to GABA which is needed during delta wave sleep. Delta wave sleep (stage 3 NREM) stimulates the release of *growth hormone and prolactin*.
Prolactin, given to mice engineered to have MS, spontaneously restored the myelin sheath...the insulation around the nerves that takes a hit from this pathway kicking in (the Kynurenine-pathway):
HERV-W is the retroviral protein believed to cause MS...the "W" stands for tryptophan.
Bb appears to have this PLG RKT. PLG = OspC = plasminogen, R= receptor, KT = keynureine-tryptophan.
MS, Lyme disease and HIV all trigger that pathway (KP) which throws off a balance between using tryptophan to *make serotonin* or breaking it down to make other chemicals (many harmful in EXCESS).
I provided a link to a picture of this imbalance in a very important post and locations where minocycline OR berberine impact that imbalance...to help restore the balance - increasing serotonin.
How does HBOT help out?
"Second, the research showed the way that adding in extra oxygen helped.
This discovery had to do with the normal brain molecule, glutamate, mentioned earlier.
In stroke, this molecule is released in excess in the body's attempt to keep the brain working.
The problem is that extra glutamate acts like a poison to nerve cells and causes damage.
Adding more oxygen helps to convert the excess glutamate into much needed energy for the cells.
A special protective factor called "GOT" (glutamate oxaloacetate transaminase)
facilitates the conversion of glutamate into fuel for the brain.
GOT makes the system work even under conditions of lower oxygen so the brain doesn't release too much toxic glutamate and damage the nerve cells."
As discoveries are made, new knowledge gradually comes to
light.
We slowly start to see the whole picture.
Let's go back for a minute to that hotel room. Before we "flip the switch" the room is dark and afterwards we can see everything.
In scientific research the process occurs step-by-step, like having a dimmer on the light switch.
Imagine walking into the same room with a switch having a dimmer and rather than turning the light on full, you turn it on slowly, a bit at a time.
Instead of seeing everything in the room at once, you would see things gradually.
First, you would see the dark outline of the bed, table and television, then a little more detail and finally, you would be able to walk over to the phone and dial.
Basic science research is very much like having a light on a dimmer switch: discovery happens gradually.
There ARE work-arounds for genetic differences. Many are just being discovered.
Undermethylation -> estrogen dominance.I've linked that previously. Ridding excess estrogen can be a problem.
"Removing excess estrogen is essential for life and to prevent many cancers. This is done primarily in the liver.
Here, many estrogens are converted to other chemicals and they are removed from the body in the bile.
This involves many detoxification pathways, including the ***glutathione***-dependent, ***selenium***-dependent P450 liver detoxification pathway.
When this does not occur correctly, a person is said to be estrogen dominant, or having too much estrogen. This is a common syndrome associated with premenstrual syndrome or PMS, uterine fibroid tumors, cancers, ovarian cysts, polycystic ovary disease or PCOS, and other female organ-related problems.
The solution for it is to restore the liver to health. Most people’s livers are very toxic today, even if all the blood tests for liver enzymes and other measures are normal."
About glutathione...we make it when we have sufficient B6 (active form is called PLP/P5P) which works with an enzyme called CBS in the "transsulfuration pathway" to lower homocysteine -> taurine (lowers cholesterol) + GSH = glutathione + Sulfate.
To rid homocysteine, we need BOTH pathways to be working...remethylation (B12, B9 = folic acid, and zinc (BHMT is a zinc dependent enzyme)as well as the transsulfuration pathway.
"SAM" (as in SAMe for depression) is in the remethylation portion.
I know...overload. Take it slowly. Print it out and read it over and over until it "clicks".
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
Is it possible for a person to experience specific autonomic dysfunction that ONLY affects the GI tract and not the heart, lungs, kidneys?
-------------------- -Razzle Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs. Posts: 4167 | From WA | Registered: Feb 2011
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posted
Razzle, I think I only had GI symptoms, although it was preceded by neck, should and left arm tingling and pain. I really think those pains were related to something in the cervical spine so it may not have been vagus nerve.
I'll never really know what caused my GI symptoms, but Lyme and H pylori treatment and other supplements did get rid of it.
-------------------- Son, 26, Dx Lyme 4/10, Babs 8/10 Had serious arthritis, all gone. Currently on Valtrex Daughter, 26,bullseye 7/11 arthritis in knees, cured and off all meds. . Self:Lyme, bart, sxs gone, no longer treating. Posts: 496 | From Washington, DC | Registered: Jul 2010
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springshowers
Frequent Contributor (1K+ posts)
Member # 19863
posted
"I remember my first LLMD telling me that she thought my vagus nerve was 'blocked' when she used some type of laser light on me. I moved on to someone else and never did quite figure out what this was, but since that time, have always felt that the bulk of my illness was around my neck and skull where I was 'blocked'."
Laser - !
Thanks for the info
Here is a good website with description and pictures...
Posts: 2747 | From Unites States Of America | Registered: Apr 2009
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Can irritation or issues with this nerve have anything to do with annoying muscle twitching and also numbness tingling (like arms constantly falling asleep at night for no apparent reason)?
posted
The Vagus nerve is supposed to be involved with some forms of tinnitus. Lyme irritation of the nerve may be why lyme patients frequently have tinnitus.
Posts: 40 | From USA | Registered: Sep 2012
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