I thought this might be helpful if you're curious about your genes and medications. This isn't an end-all, be-all list (there are other lists and info out there).
I had a horrible time on rifampin and later found out I just don't have the genes to process it.
I'm not a medical person, so please don't take this as advice from me as to what you should or shouldn't take.
I just found it very interesting and helpful for me.
Posts: 2839 | From California | Registered: Jul 2012
| IP: Logged |
TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
Wow, Judie, you are going to get me digging my genetic info back out, now!
That is quite the pdf! Thanks so much.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
| IP: Logged |
posted
Where does someone get this genetic testing done? And what for, sorry I just dont know anything about this
Posts: 908 | From Albany | Registered: Nov 2008
| IP: Logged |
TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
Most have gotten it done through 23andme.com. They send you a kit. You give a simple saliva sample and send it back to them and they email you when your results are in (which is 4-6 weeks). The test is very affordable ($99)
You have to set up an user account on their website to access the results, but then you can download right from their site to your computer.
Since they don't give health analysis with their results at the present time (FDA has halted that part of their service pending a review).
But you can run your raw info through Geneticgenie.com and they will give you your detox and methylation panels, since that is big part of the reason most people get the test done.
It is very helpful for so many things... a goldmine of personal genetic info that can help you with everything from pinpointing your detox issues and fixes, to knowing which drugs you can or cannot take. It can help uncover your propensity for certain types of cancers. etc.
Hopefully, the FDA will clear 23andme to once again give health analysis again.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
| IP: Logged |
Judie
Frequent Contributor (1K+ posts)
Member # 38323
posted
Here's a thread I started awhile back on what to do with the data:
I looked at some of your references. How did you tell that you can't take rifampin?
Posts: 833 | From Somewhere | Registered: Nov 2010
| IP: Logged |
TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
Yes, Judie,
Try to help us understand why you can't take rifampin (besides your horrible reaction to it). I looked at the pdf you gave from your levaquin thread, and I cannot get it with that either,
except that I understand you are very chemically sensitive (like I have been), and that possibly could be why you cannot handle rifampin. But I'm not understanding why from the info on the genetics.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
| IP: Logged |
TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
Sorry, the pdf was from this thread, but you mentioned you were homozygous for CYP1B1 (Cytochrome P450 1B1) on the levaquin thread.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
| IP: Logged |
posted
Wow thanks. Very affordable. I figured it would be thousands.
Posts: 908 | From Albany | Registered: Nov 2008
| IP: Logged |
Judie
Frequent Contributor (1K+ posts)
Member # 38323
posted
I tried looking up the rifampin info online (it was a different chart), but the info has been deleted. I had printed out the info awhile back and was referring to my printed copy.
I think the health advice, med part, must have been removed because of the whole 23andme thing. It was part of a genetic test for Genova and the link goes to a different place now.
For CYP1B1, it said to avoid inducers and Rifampin was on the list along with other things I know I react to.
I'm also homozygous for CYP2D6 which makes me a poor metabolizer (mixed in with some other messed up genes for processing meds).
Here's some more info with a chart towards the bottom:
The CDSA test by genova has a section on genes and antibiotic interactions too (at least that one use to, but I don't know now, it looks like they changed the info on some of their tests).
Here's a paper on the topic:
Pharmacogenomic testing: Relevance in medical practice Why drugs work in some patients but not in others
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
Printer-friendly view of this topic