LymeNet Flash: IgM positive and IgG negative opinions?

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»	LymeNet Flash » Questions and Discussion » Medical Questions » IgM positive and IgG negative opinions?

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Topic: IgM positive and IgG negative opinions?

elara
Member
Member # 41819

posted

I'd like opinion on an Igenex test result? Plus I'd be curious how many others have seen this in chronic long term illness rather than a new infection?

Western Blot IgM CDC and IGgenex positive

18 kDa +
23-25 kDa +++
31 kDa IND
39 kDA IND
41 kDa +
83 kDa IND

Western Blot IgG

39 kDa IND
41 kDa +

Multiplex PCR negative

IFA Bb negative

Seems od the IgM would be so positive in a late infection with no positive IgG's except the Flagellen 41

Could this be an EBV cross reaction?

Repeat opinions?

thanks

Posts: 53 | From Jupiter | Registered: Aug 2013 | IP: Logged |

Keebler
Honored Contributor (25K+ posts)
Member # 12673

posted

-
With lyme, IgM and IgG is often sort of "flipped" from what one might expect in other infections.

IgM is usually a big flag for persistent / chronic (and therefore very much active) in lyme. But any positive band, either IgM or IgG is an important flag. See the Western Blot article here, explaining it:

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=2;t=015508;p=0

Diagnosing Lyme Disease (&/or whatever else is going on)

http://www.anapsid.org/lyme/lymeseroneg.html

Reasons for False Negative (Seronegative) Test Results in Lyme Disease
-

[ 02-19-2015, 10:40 PM: Message edited by: Keebler ]

Posts: 48021 | From Tree House | Registered: Jul 2007 | IP: Logged |

Lymetoo
Moderator
Member # 743

posted

Either way, IgG or IgM .. it needs to be treated.

Dr C of MO says if either one is positive, it is positive and needs to be treated.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96239 | From Texas | Registered: Feb 2001 | IP: Logged |

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