Topic: Elevated liver enzymes from arteminisin or cat's claw?
ArtistDi
Frequent Contributor (1K+ posts)
Member # 2297
posted
Anyone have elevated liver enzymes from either arteminisin or cat's claw?
Never had elevations on IV antibiotics and now I have slight elevation, so trying to figure it out.
Posts: 1567 | From Hatfield, MA, USA | Registered: Mar 2002
| IP: Logged |
ArtistDi
Frequent Contributor (1K+ posts)
Member # 2297
posted
Up
Posts: 1567 | From Hatfield, MA, USA | Registered: Mar 2002
| IP: Logged |
posted
I think the only time hubby ever had elevated liver enzymes was on artemisinin. This happened one or two times when he tried to ramp up on that herb too quickly. The numbers came down pretty quickly.
It has been so long ago I can't remember if we stopped the herb or just decreased the dose. I do know that at times during treatment he took much higher doses of art that did not effect his liver enzymes.
Would not advise taking only art as an herbal babs treatment. It takes combos of herbs just like it takes combos of meds to treat babs.
Bea Seibert
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
| IP: Logged |
TerryK
Frequent Contributor (5K+ posts)
Member # 8552
posted
Happened to me. Later I found out I had parasites. I think that *could* be why it elevated my liver enzymes. An abundance of die off. Could probably be other reasons as well.
Posts: 6286 | From Oregon | Registered: Jan 2006
| IP: Logged |
TerryK
Frequent Contributor (5K+ posts)
Member # 8552
"Elevated liver enzymes have been observed in patients treated for malaria with artemisinins but are generally thought to have resulted from the underlying malaria rather than the artemisinins"
Posts: 6286 | From Oregon | Registered: Jan 2006
| IP: Logged |
TerryK
Frequent Contributor (5K+ posts)
Member # 8552
The mechanism by which artemisinin derivatives cause liver injury is unknown. Clinical factors and testing for serum antibodies suggest an idiosyncratic immunological reaction to a hepatic metabolite may be responsible. Artemisinin derivatives are extensively metabolized by the liver (primarily via CYP 3A4) and are prone drug-drug interactions if given with strong CYP 3A4 inducers such as rifampin, phenytoin or St. John's wort or inhibitors such as intraconazole or ritonavir.
Posts: 6286 | From Oregon | Registered: Jan 2006
| IP: Logged |
Bea Seibert
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- What kind of liver support are you doing? Perhaps that might need to be altered. -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/