It has been demonstrated that defects in TLR1 and TLR2 can
abrogate the response to
OspA in OspA-vaccinated mice.
The absence of TLR2-dependent signalling could result in disruption of the host inflammatory response mediated by macrophages
Once the density of spirochaetes in joints reaches a particular threshold, pro-inflammatory signalling could be activated and may result in severe arthritis in mice,
regardless of the number of spirochaetes.
In the TLR2-deficient mouse, it is also possible that spirochaetes were cleared by other host defence mechanisms independent of the TLR2 pathway.
TLR2-independent pathways could be mediated by non-lipoprotein components of spirochaetes, such as flagellin, CpG motif-containing DNA and glycolipids
Neutrophils have been shown to play a critical role in spirochaete clearance, and may be very important in controlling numbers of Ig-opsonised B. burgdorferi in TLR2-deficient mice.
It can be hypothesised that ***spirochaetal products***, e.g., lipoproteins, flagellin or others, could be present in the joint as potential ligands of TLRs.
Liu et al. have demonstrated that MyD88 deficiency impairs pathogen clearance, but does not alter inflammation in Borrelia-infected mice .
Bolz et al. observed that MyD88-deficient mice had
extremely high numbers of B. burgdorferi in tissues when compared with wild-type litter-mates, and
Do you know what TCDD is besides the most potent inducer of CYP1A1? Google it.
Think it is in our environment? And many of our now older soldiers were massively exposed to it?
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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Brussels
Frequent Contributor (5K+ posts)
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COPY PASTE OF the ARTICLE
No surprise: Antibiotics make Lyme disease symptoms worse
Once the cell walls of a Lyme disease patient has been destructed, Dr. Rau claims that antibiotics only make symptoms worse.
Working with patients for many years, he says that patients are only treatable with a biological medicine called Pleo-Sanum Haptens – which is an antigen absorber.
Additionally, the doctor places patients under a strict regimen that begins with detoxification.
Intestinal healing and regeneration are the next steps which include nutrition and supplements. His protocol has helped his patients overcome the symptoms of Lyme disease.
About the author: Abby Campbell is a medical, health, and nutrition research writer. She’s dedicated to helping people live a healthy lifestyle in all aspects – physically, mentally, emotionally, and spiritually. Abby practices, writes, and coaches on natural preventive care, nutritional medicine, and complementary and alternative therapy.
Brussels
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posted
Vaccine viruses are co-factors of Lyme disease
Dr. Rau describes a situation in a Swiss community of farmers where there is an extreme vulnerability to Lyme disease due to the environmental breeding ground for ticks.
His clinic conducted examinations on all farmers and their families, and an astronomical 80 % were diagnosed with the disease.
However, only 2% exhibited symptoms.
It turned out that the majority of those diagnosed were able to heal on their own.
Therefore, they set out to find the reason some people were more susceptible to the debilitating symptoms.
In his investigation, Dr. Rau discovered the difference between those who healed on their own from those who could not.
Those who could not heal on their own also had viruses.
In fact, 100 percent of them had viruses – particularly cytomegalia and chlamydia.
These underlying viruses and toxicity such as heavy metals – added to the stress of the immune system.
With his discovery, Dr. Rau’s continued investigation led to other revelations.
He also determined specific vaccine viruses that were also cofactors:
In addition, Dr. Rau detected another important paradigm about Lyme disease.
All Stage 3 patients – 100 percent of them – had severely unbalanced fatty acid and phospholipid profiles.
Arachidonic acid and palmitic acid levels were elevated, and linoleic acid was extremely inflated.
Additionally, levels of omega-3 were deficient.
This imbalance causes inflammation and enhances membrane destruction.
In fact, it favors the chronification of viruses while weakening the lipophilic parts of the cell walls which sets up the stage for autoimmune symptoms.
Posts: 6199 | From Brussels | Registered: Oct 2007
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Marnie
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Abx. maybe ineffective *alone* (as well as impacting beneficial bacteria negatively).
BUT...think about combining abx. with D-mannose and throwing in Claritin.
D-Mannose to "lure" (it is not unusual to combine a "sugar" with abx. to increase effectiveness!)
p8 in the tick's saliva inhibits the "mannose binding lectin pathway" - the FIRST pathway our immune system is supposed to respond to an invader by cleaving (chopping apart) certain proteins (antigens) in order to mount the correct immune response.
IgG1K (antibody) to Bb's OspB is kapoot. it is an inhibitor to *histamine release*!
Remember the "fab" portion of our antibody to OspB was impacted negatively and Mg + Ca restored it?
Mg is an anti-histamine (plus anti-inflammatory, and inhibits HMGCoA reductase - lowers cholesterol).
Substitute Claritin as anti-histamine to work on H1 macrophage receptors which may have been triggered due to a tick's histamine releasing factor in its saliva.
Minocycline to destroy.
Lure w/ D-Mannose Destroy w/minocycline Prevent reaction w/Claritin (and for other reasons).
MAYBE.
BTW...p8 (in the tick's saliva) looks to be a COMPONENT of HTLV-1 (which looks to need p12 too). HTLV-1 is a virus - p8 in the tick's saliva is *one protein* in a nasty virus.
Doxycycline, if lyme is addressed immediately, is effective for MOST persons. It alters our immune response. But...depending on genetics (MTHFR as well as Hereditary hemochromatosis)/ co-infections / load, it might not work in all cases.
"The exact mechanism of ***T-cell response suppression by doxycycline*** remains to be elucidated"...
cottonbrain
Frequent Contributor (1K+ posts)
Member # 13769
posted
Thank you so much for this interesting article. It makes me wonder, what can we do?
Can someone interpret for us lay people:
How do we check our fatty acid / phospholipid profiles?
Will killing the viruses resolve the probem and allow antibiotics to work?
Is Pleo-Sanum Haptens available and safe?
Who is this guy? Is he legit?
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Brussels
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this Swiss clinic is very well known. I live in Switzerland...
I discovered it when I was already treating with dr. K's practioners, so I didn't go there, as I got better from lyme.
I find it is interesting to know that 80 % of farmers he analyzed had borrelia in their bodies!!
But only a small percentage were sick with lyme.
I KNOW many of my neighbors, I live in the country side, almost EVERYBODY is bitten by ticks in a regular base here.
I got sick with debilitating lyme symptoms after my FIRST BITE EVER. My daughter got sick after her FIRST TICK BITE too (at the age of 1).
I know all these people being bitten by ticks, and they DO NOT FALL SICK with lyme like we did.
There is much more than BACTERIA making people sick.
Now I still get bitten, about 5, 6 times a year, but I do not fall sick with lyme. So does my daughter. Why?
I guess he is talking about VACCINES that create INFLAMMATION in the body, by injecting viruses.
By treating viruses, you probably diminish the amount of inflammation, and give more chance for your immune system to go fight other things than viruses in low grade infections.
Pleo Sanum are the Sanum products I keep talking about here for years.
They are WIDELY used in Germany and Switzerland by doctors and naturopaths. Before, they were all prescription free. Now the pharma mafia is coming to try to block them.
Dr. K. uses them largely, for decades.
In Switzerland, we need prescription for them now. But it was not like that a year ago or so.
The pharma knows they are very effective as anti-infectious products. Against strep, staphil, E.coli, and many types of candida or fungal infection.
That was what kept my candida going in remission for the last 7 years or so. Nothing else worked.
They are nosodes or haptens basically (there are 2 types of products). It is very easy to use if you know what you have as trouble (which pathogen is infecting you). No side effects, that I know.
Sanum is basically what I used to put most infections dormant. I used photons and nosodes to put my borrelia dormant, then Sanum nosodes to make the rest dormant.
It makes your body kill the pathogens. It is not a chemical killer.
Posts: 6199 | From Brussels | Registered: Oct 2007
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also Brussels, Dr. Nicholas Gonzales, famous for curing cancer with enzymes and recently murdered by the medical mafia for using GcMaf, says the following regarding enzyme therapy...
"Trypsin and other enzyme protein digesters are used, cancer cells attract the enzymes due to their electrical charge. Cancer cells have a protein coating with a neg. electrostatic charge. the immune cells white cells and others have a neg charge also..so they cannot work together.
If you are eating foods with a lot of meat proteins you will use most of the digestive enzymes and little left over to do anything else. If you are vegetarian you have surplus enzymes that strip the neg charge and make the cancer cell vulnerable to a pos. charge of the immune system." (macrophages have a positive charge)
Could this reflect why the violet ray is effective? actually changing the electrical potential of virus, bacteria etc. causing their death?
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